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Nolatrexed is a
thymidylate synthase inhibitor Thymidylate synthase inhibitors are chemical agents which inhibit the enzyme thymidylate synthase and have potential as an anticancer chemotherapy. This inhibition prevents the methylation of C5 of deoxyuridine monophosphate (dUMP) thereby inhibiti ...
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References

4-Pyridyl compounds Thioethers Quinazolines Lactones Thymidylate synthase inhibitors {{organic-compound-stub