Nifoxipam (3-hydroxydesmethylflunitrazepam, DP 370) is a
benzodiazepine
Benzodiazepines (BZD, BDZ, BZs), sometimes called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, ...
that is a minor
metabolite
In biochemistry, a metabolite is an intermediate or end product of metabolism.
The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, c ...
of
flunitrazepam
Flunitrazepam, also known as Rohypnol among other names, is a benzodiazepine used to treat severe insomnia and assist with anesthesia. As with other hypnotics, flunitrazepam has been advised to be prescribed only for short-term use or by those ...
and has been sold online as a
designer drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Des ...
.
Nifoxipam produces strong tranquillising and sleep-prolonging effects and has much lower toxicity compared to
lormetazepam
Lormetazepam, sold under the brand name Noctamid among others, is a drug which is a short to intermediate acting 3-hydroxy benzodiazepine derivative and temazepam analogue. It possesses hypnotic, anxiolytic, anticonvulsant, sedative, and skel ...
and flunitrazepam in mice.
See also
*
List of benzodiazepine designer drugs
The below tables contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, al ...
*
Nitrazolam
Nitrazolam is a triazolobenzodiazepine (TBZD)
, which are benzodiazepine (BZD) derivatives, that has been sold online as a designer drug.
It is closely related to Clonazolam or Flunitrazolam, only differing by the removal of a Chlorine or Fluo ...
*
Nitemazepam
*
Phenazepam
Phenazepam (also known in Russia as bromdihydrochlorphenylbenzodiazepine) is a benzodiazepine drug, which was developed in the Soviet Union in 1975, and now produced in Russia and some CIS countries.
Phenazepam is used in the treatment of vari ...
References
Designer drugs
Fluoroarenes
GABAA receptor positive allosteric modulators
Glycine receptor antagonists
Lactams
Nitrobenzodiazepines
Lactims
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