neXtProt is an on-line knowledge platform on human

proteins Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

. It strives to be a comprehensive resource that provides a variety of types of information on human proteins, such as their function, subcellular location, expression, interactions and role in diseases. The major part of the information in neXtProt is obtained from the UniProt Swiss-Prot

database In computing, a database is an organized collection of data stored and accessed electronically. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases sp ...

but it is complemented by data originating from high-throughput studies with an emphasis on

proteomics Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...

. neXtProt offers also an advanced search capacity based on the SPARQL technology as well as an API that allows to programatically extract the data stored in the resource. It is developed by the CALIPHO groupCALIPHO group
on the web site of the SIB directed by Amos Bairoch and Lydie Lane of the

Swiss Institute of Bioinformatics The SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation which federates bioinformatics activities throughout Switzerland. The institute was established on 30 March 1998 and its mission is to provide core bioinfor ...

(SIB).

References

External links

neXtProt
- Exploring the universe of human proteins
UniProt
- The Universal protein resource
SIB
- The Swiss Institute of Bioinformatics
GitHub directory for neXtProt code
{{Biology-footer Molecular biology Biological databases Human biology Human proteins