New fuchsine is an organic compound with the
formula
In science, a formula is a concise way of expressing information symbolically, as in a mathematical formula or a ''chemical formula''. The informal use of the term ''formula'' in science refers to the general construct of a relationship betwee ...
H2N(CH3)C6H3)3Cl. It is a green-colored solid that is used as a
dye
A dye is a colored substance that chemically bonds to the substrate to which it is being applied. This distinguishes dyes from pigments which do not chemically bind to the material they color. Dye is generally applied in an aqueous solution an ...
of the
triarylmethane class. It is one of the four components of basic
fuchsine
Fuchsine (sometimes spelled fuchsin) or rosaniline hydrochloride is a magenta dye with chemical formula C20H19N3·HCl. , and one of the two that are available as single dyes. The other is
pararosaniline
Pararosaniline, Basic Red 9, or C.I. 42500 is an organic compound with the formula H2NC6H4)3Cl. It is a magenta solid with a variety of uses as a dye. It is one of the four components of basic fuchsine. (The others are rosaniline, new fuchsine a ...
. It is prepared by condensation of
ortho-toluidine with formaldehyde. This process initially gives the
benzhydrol 4,4'-bis(dimethylamino)benzhydrol
4,4′-Bis(dimethylamino)benzhydrol is an organic compound with the formula (Me2NC6H4)2CH(OH), where Me is methyl. It is a white solid that is soluble is a variety of organic solvents. The compound is notable as the reduced derivative of Michle ...
, which is further condensed to give the leuco (colorless)
tertiary alcohol
In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl () functional group bound to a saturated carbon atom. The term ''alcohol'' originally referred to the primary alcohol ethanol (ethyl alcohol), whic ...
[(H
2N(CH
3)C
6H
3)
3COH, which is oxidized in acid to give the dye.
Use as dye and stain
New fuchsine is used to dye polyacrylonitrile, paper, and leather. In biology, it can be used for staining (biology), staining acid-fast organisms, e.g. by Ziehl–Neelsen stain, and for making Schiff's reagent. As a primary amine, the dye can be diazotized in the laboratory, and the resulting diazonium salt used as a trapping agent in enzyme histochemistry.
[Lojda Z, Gossrau R, Schiebler TH (1979) Enzyme Histochemistry. A Laboratory Manual. Berlin: Springer-Verlag.]
Etymology
The name fuchsine recognizes
Leonhart Fuchs
Leonhart Fuchs (; 17 January 1501 – 10 May 1566), sometimes spelled Leonhard Fuchs and cited in Latin as ''Leonhartus Fuchsius'', was a German physician and botanist. His chief notability is as the author of a large book about plants and th ...
.
See also
*
Fuchsine
Fuchsine (sometimes spelled fuchsin) or rosaniline hydrochloride is a magenta dye with chemical formula C20H19N3·HCl.
*
Pararosaniline
Pararosaniline, Basic Red 9, or C.I. 42500 is an organic compound with the formula H2NC6H4)3Cl. It is a magenta solid with a variety of uses as a dye. It is one of the four components of basic fuchsine. (The others are rosaniline, new fuchsine a ...
References
External links
New Fuchsin - StainsFile
{{DEFAULTSORT:New Fuchsine
Triarylmethane dyes
IARC Group 2B carcinogens
Anilines