Neuropeptide Y receptor type 5 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the ''NPY5R''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Selective ligands
Agonists
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Neuropeptide Y
Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. NPY has been identified as the most abundant peptide present in the ma ...
(endogenous agonist, non subtype selective)
* BWX-46 (selective NPY
5 agonist, CAS# 172997-92-1)
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Peptide YY
Peptide YY (PYY) also known as peptide tyrosine tyrosine is a peptide that in humans is encoded by the gene. Peptide YY is a short (36-amino acid) peptide released from cells in the ileum and colon in response to feeding. In the blood, gut, a ...
Antagonists
* CGP-71683 (CAS# 192322-50-2)
* FMS-586
* L-152,804 (CAS# 6508-43-6)
*
Lu AA-33810
* MK-0557
* NTNCB (CAS# 486453-65-0)
*
Velneperit (S-2367)
See also
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Neuropeptide Y receptor
References
Further reading
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External links
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G protein-coupled receptors
{{transmembranereceptor-stub