Neoflavonoids are a class of polyphenolic compounds. While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, neoflavonoids have the 4-phenylchromen backbone with no hydroxyl group substitution at position 2.

Types

Neoflavonoids include 4-arylcoumarins (neoflavones), 4-arylchromanes, dalbergiones and dalbergiquinols. * Neoflavones are derived from the 4-phenylcoumarin (or 4-aryl-

coumarin Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered h ...

) backbone (C₁₅H₁₂O₂). The first neoflavone isolated from natural sources was calophyllolide from ''

Calophyllum inophyllum ''Calophyllum inophyllum'' is a large evergreen plant, commonly called tamanu, oil-nut, mastwood, beach calophyllum or beautyleaf. It is native to tropical Asia and Wallacea. Due to its importance as a source of timber for the traditional shi ...

'' seeds (1951). It is also known to found in bark and timber of Sri Lankan endemic plant '' Mesua thwaitesii''. * Neoflavenes possess the 4-phenylchromen backbone (C₁₅H₁₀O₂). Dalbergichromene, extracted from the stem-bark and heartwood of ''

Dalbergia sissoo ''Dalbergia sissoo'', known commonly as North Indian rosewood or ''shisham'', is a fast-growing, hardy, deciduous rosewood tree native to the Indian subcontinent and southern Iran. ''D. sissoo'' is a large, crooked tree with long, leathery leav ...

'', is an example of such compounds

Other examples

* Coutareagenin (5-hydroxy-7-methoxy-4-(3,4-dihydroxyphenyl)-2H-benzo-1-pyran-2-on) found in '' Hintonia latiflora'' * Dalbergin * Nivetin isolated from '' Echinops niveus''

References

External links

{{Flavonoids