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Nebula Genomics is a
personal genomics Personal genomics or consumer genetics is the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different techniques, including single-nucleotide polymorphi ...
company based in San Francisco, California. It offers a
whole-genome sequencing Whole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a ...
service.


History

Nebula Genomics was co-founded in 2018 by George Church, geneticist at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
. In August 2018, Nebula Genomics announced a seed funding round of $4.3 million led by
Khosla Ventures Khosla Ventures is an American venture capital firm founded by Vinod Khosla, focused on early-stage companies in the Internet, computing, mobile, financial services, agriculture, healthcare and clean technology sectors. Some of its most successfu ...
. In September 2019, the company announced it intended to deploy an anonymous genetic testing service. In February 2020, Nebula Genomics began offering high-coverage whole-genome sequencing for $299 internationally. The service also requires a subscription to Nebula Explore. On 11 August 2021, ''ProPhase Labs'', a diversified medical science and technology company, announced the acquisition of Nebula Genomics by its recently formed subsidiary, ''ProPhase Precision Medicine, Inc.'', for about $14.6 million in a combination of ProPhase Labs common stock and cash.


Privacy concerns


Relationship with BGI Group

BGI Group BGI Group, formerly Beijing Genomics Institute, is a Chinese genomics company with headquarters in Yantian District, Shenzhen. The company was originally formed in 1999 as a genetics research center to participate in the Human Genome Project. It ...
is a Chinese life sciences company that has been part of many controversies, especially regarding genetic data. One of these concerns one of the most popular prenatal test in the world,
Reuters Reuters ( ) is a news agency owned by Thomson Reuters Corporation. It employs around 2,500 journalists and 600 photojournalists in about 200 locations worldwide. Reuters is one of the largest news agencies in the world. The agency was estab ...
found out that it has been developed with the involvement of Chinese's army, People's Liberation Army (PLA), and has been used to collect genetic data from millions of women. George Church, the co-founder of Nebula Genomics, has served on the BGI Group's scientific advisory board since 2007. In 2017, BGI established the ''George Church Institute of Regenesis'', a research collaboration between Church’s lab and about a dozen staffers at BGI in China. On 18 February 2020, Nebula Genomics has also announced that has partnered up with BGI: the saliva samples sent for decoding to Nebula Genomics are then sent by the company to BGI labs in Hong Kong for sequencing, although nowadays Nebula Genomics states in its FAQs that the samples are sequenced in Europe. Nebula Genomics said that this partnership is made to bring down the cost of whole-genome sequencing since normally it has a cost that makes it inaccessible to most people.


Use by law enforcement and risk of data breaches

Nebula Genomics says that it is developing its own
blockchain A blockchain is a type of distributed ledger technology (DLT) that consists of growing lists of records, called ''blocks'', that are securely linked together using cryptography. Each block contains a cryptographic hash of the previous block, a ...
to enforce security and privacy but, despite that, re-identification of people starting from the genetic data could still be possible (DNA itself is a unique identifier), law enforcement could still issue search warrants or subpoena the data and this technology, given also the fact that is hard to implement, could still be vulnerable to data breaches. This is also stated in Nebula Genomics' Privacy Policy: "However, under certain circumstances your genetic information may be subject to processing pursuant to laws, regulations or judicial or governmental orders, warrants or subpoenas. In other words, a lawful demand by public authorities may require we share your personal Information", they also state that: "We may share your personal data if we believe it is reasonably necessary to enforce the Nebula Terms and Conditions, protect the security and integrity of our Services, or protect the rights, safety, or property of Nebula, our employees or users". About data breaches risk it's written that: "While we cannot guarantee that loss, access or misuse of data will not occur, we use reasonable efforts to prevent these outcomes."


Technology

Nebula Genomics develops technologies to enable controllable, transparent and secure genomic data sharing. It is also developing approaches for privacy-preserving analysis of genomic datasets.


Awards

In 2019, Nebula Genomics won the “Best-in-Show” award at the SXSW Pitch competition, part of the
South by Southwest South by Southwest, abbreviated as SXSW and colloquially referred to as South By, is an annual conglomeration of parallel film, interactive media, and music festivals and Convention (meeting), conferences organized jointly that take place in m ...
festival.


References

{{Reflist


External links


Nebula Explore

Review of Nebula Genomics
Genetic genealogy companies Biotechnology companies of the United States 2018 establishments in California