National Institute Of Nutrition
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The National Institute of Nutrition (NIN) is an Indian
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
,
nutrition Nutrition is the biochemical and physiological process by which an organism uses food to support its life. It provides organisms with nutrients, which can be metabolized to create energy and chemical structures. Failure to obtain sufficient n ...
and
translational research Translational research (also called translation research, translational science, or, when the context is clear, simply translation) is research aimed at translating (converting) results in basic research into results that directly benefit humans. ...
centre located in
Hyderabad Hyderabad ( ; , ) is the capital and largest city of the Indian state of Telangana and the ''de jure'' capital of Andhra Pradesh. It occupies on the Deccan Plateau along the banks of the Musi River (India), Musi River, in the northern part ...
,
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
. The institute is one of the oldest research centres in India, and the largest centre, under the
Indian Council of Medical Research The Indian Council of Medical Research (ICMR), the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest and largest medical research bodies in the world. The ICMR is funded by the Gove ...
, located in the vicinity of
Osmania University Osmania University is a collegiate public state university located in Hyderabad, Telangana, India. Mir Osman Ali Khan, the 7th Nizam of Hyderabad in 1918 , He released a farman to establish OSMANIA UNIVERSITY on the day of 28 August 1918. It ...
. The institute has associated clinical and paediatric nutrition research wards at various hospitals such as the
Niloufer Hospital Niloufer Hospital is housed in a building in the heart of historic Hyderabad and has an interesting past. This reputed institution was founded in 1949 by the Princess Niloufer. Princess Niloufer was the daughter of king of Ottoman Empire (Turkey ...
for Women and Children, the Government Maternity Hospital, the
Gandhi Medical College Gandhi Medical College (founded 14 September 1954) is a medical college in Hyderabad, India affiliated with Kaloji Narayana Rao University of Health Sciences. The college was originally affiliated to NTR University of Health Sciences. Histor ...
and the
Osmania General Hospital Osmania General Hospital (OGH) is one of the oldest hospitals in India located at Afzal Gunj, Hyderabad Hyderabad ( ; , ) is the capital and largest city of the Indian state of Telangana and the ''de jure'' capital of Andhra Pradesh. I ...
in Hyderabad. The National Centre for Laboratory Animal Science (to be integrated into the ''
National Animal Resource Facility for Biomedical Research The National Animal Resource Facility for Biomedical Research is an Indian Biomedical research facility, and vivarium under the Indian Council of Medical Research. The new 33rd flagship institute of ICMR was founded in 2015, at Genome Valley in ...
''), the Food and Drug Toxicology Research Centre, the National Nutrition Monitoring Bureau are the other wings of NIN,ICMR's Institutes/Centres
(scroll down page to find NIN)
for India's
Ministry of Health and Family Welfare The Ministry of Health and Family Welfare is an Indian government ministry charged with health policy in India. It is also responsible for all government programs relating to family planning in India. The Minister of Health and Family Welfare ...
. The institute also derives funding from the Indian
Department of Biotechnology The Department of Biotechnology (DBT) is an Indian government department, under the Ministry of Science and Technology responsible for administrating development and commercialisation in the field of modern biology and biotechnology in India. It ...
. The institute majorly conducts research in
obesity Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's we ...
,
diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...
,
food chemistry Food chemistry is the study of chemical processes and interactions of all biological and non-biological components of foods. The biological substances include such items as meat, poultry, lettuce, beer, milk as examples. It is similar to biochemist ...
,
dietetics A dietitian, medical dietitian, or dietician is an expert in identifying and treating disease-related malnutrition and in conducting medical nutrition therapy, for example designing an enteral tube feeding regimen or mitigating the effects of ca ...
, clinical
toxicology Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating expo ...
, and
micronutrient Micronutrients are nutrient, essential dietary elements required by organisms in varying quantities throughout life to orchestrate a range of physiological functions to maintain health. Micronutrient requirements differ between organisms; for exam ...
deficiency in collaboration with centres such as the
Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...
,
University of Colorado School of Medicine The University of Colorado School of Medicine is the medical school of the University of Colorado system. It is located at the Anschutz Medical Campus in Aurora, Colorado, one of the four University of Colorado campuses, six miles east of downtown ...
,
Washington University Washington University in St. Louis (WashU or WUSTL) is a private research university with its main campus in St. Louis County, and Clayton, Missouri. Founded in 1853, the university is named after George Washington. Washington University is r ...
, and the
Johns Hopkins Bloomberg School of Public Health The Johns Hopkins Bloomberg School of Public Health is the public health graduate school of Johns Hopkins University, a private research university in Baltimore, Maryland. As the second independent, degree-granting institution for research in epi ...
in the US, and the
University of Wollongong The University of Wollongong (abbreviated as UOW) is an Australian public research university located in the coastal city of Wollongong, New South Wales, approximately 80 kilometres south of Sydney. As of 2017, the university had an enrolment of ...
in
Australia Australia, officially the Commonwealth of Australia, is a Sovereign state, sovereign country comprising the mainland of the Australia (continent), Australian continent, the island of Tasmania, and numerous List of islands of Australia, sma ...
.


History

The Institute was founded in 1918 by Sir
Robert McCarrison Major-General Sir Robert McCarrison, CIE, FRCP (15 March 1878 – 18 May 1960) was a Northern Ireland physician and nutritionist in the Indian Medical Service, who was made a Companion of the Indian Empire (CIE) in 1923, (See p.3946 for list ...
. It was originally a single room laboratory at the Pasteur Institute,
Coonoor Coonoor, natively spelt as Kunnur (), is a Taluk and a municipality of the Nilgiris district in the Indian State of Tamil Nadu. As of 2011, the town had a population of 45,494. Demographics According to 2011 census, Coonoor had a population ...
,
Tamil Nadu Tamil Nadu (; , TN) is a States and union territories of India, state in southern India. It is the List of states and union territories of India by area, tenth largest Indian state by area and the List of states and union territories of India ...
for the study of
Beriberi Thiamine deficiency is a medical condition of low levels of thiamine (Vitamin B1). A severe and chronic form is known as beriberi. The two main types in adults are wet beriberi and dry beriberi. Wet beriberi affects the cardiovascular system, r ...
, and was called the ''Beri-Beri Enquiry Unit''. McCarrison was invalided to Britain from 1920–1922, and in 1923 the enquiry was axed on financial grounds. It was restored two years later as the ''Deficiency Disease Inquiry'', which McCarrison headed from 1925–1929. The scope of the laboratory expanded to include all deficiency diseases, and around 1928–1929 became the Nutrition Research Laboratories (NRL), with McCarrison as its first Director, until his retirement in 1935, when he was succeeded by Dr. W.R. Ackroyd. The facility moved to
Hyderabad Hyderabad ( ; , ) is the capital and largest city of the Indian state of Telangana and the ''de jure'' capital of Andhra Pradesh. It occupies on the Deccan Plateau along the banks of the Musi River (India), Musi River, in the northern part ...
in 1958 and in 1969 was renamed the National Institute of Nutrition.


Research

The institute carries out research and patent development in
clinical nutrition Clinical nutrition centers on the prevention, diagnosis, and management of nutritional changes in patients linked to chronic diseases and conditions primarily in health care. Clinical in this sense refers to the management of patients, including no ...
,
outcomes research Outcomes research is a branch of public health research which studies the end results ( outcomes) of the structure and processes of the health care system on the health and well-being of patients and populations. According to one medical outcomes an ...
,
pharmacology Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemica ...
,
pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...
,
toxicology Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating expo ...
,
food chemistry Food chemistry is the study of chemical processes and interactions of all biological and non-biological components of foods. The biological substances include such items as meat, poultry, lettuce, beer, milk as examples. It is similar to biochemist ...
,
endocrinology Endocrinology (from '' endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental event ...
,
molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physi ...
,
regenerative medicine Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by st ...
,
community A community is a social unit (a group of living things) with commonality such as place, norms, religion, values, customs, or identity. Communities may share a sense of place situated in a given geographical area (e.g. a country, village, tow ...
nutrition Nutrition is the biochemical and physiological process by which an organism uses food to support its life. It provides organisms with nutrients, which can be metabolized to create energy and chemical structures. Failure to obtain sufficient n ...
,
ophthalmology Ophthalmology ( ) is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medic ...
, and
sports nutrition Sports nutrition is the study and practice of nutrition and diet with regards to improving anyone's athletic performance. Nutrition is an important part of many sports training regimens, being popular in strength sports (such as weightlifting and ...
. Agencies such as
WHO Who or WHO may refer to: * Who (pronoun), an interrogative or relative pronoun * Who?, one of the Five Ws in journalism * World Health Organization Arts and entertainment Fictional characters * Who, a creature in the Dr. Seuss book ''Horton Hear ...
and
FAO The Food and Agriculture Organization of the United Nations (FAO)french: link=no, Organisation des Nations unies pour l'alimentation et l'agriculture; it, Organizzazione delle Nazioni Unite per l'Alimentazione e l'Agricoltura is an intern ...
recognised the institute as a ''Centre for excellence'' in food quality, safety and nutrition research. The institute is equipped with facilities including animal housing,
In vivo Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and ...
imaging Imaging is the representation or reproduction of an object's form; especially a visual representation (i.e., the formation of an image). Imaging technology is the application of materials and methods to create, preserve, or duplicate images. ...
, automated
electrophoresis Electrophoresis, from Ancient Greek ἤλεκτρον (ḗlektron, "amber") and φόρησις (phórēsis, "the act of bearing"), is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric fie ...
,
flow cytometry Flow cytometry (FC) is a technique used to detect and measure physical and chemical characteristics of a population of cells or particles. In this process, a sample containing cells or particles is suspended in a fluid and injected into the flo ...
,
DNA Microarray A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to ...
, liquid chromatography–mass spectrometry, atomic absorption spectroscopy,
matrix-assisted laser desorption/ionization In mass spectrometry, matrix-assisted laser desorption/ionization (MALDI) is an ionization technique that uses a laser energy absorbing matrix to create ions from large molecules with minimal fragmentation. It has been applied to the analysis of ...
, scanning electron microscope, confocal laser scanning microscopy, Transmission electron microscopy,
DNA sequencer A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the order of the four bases: G (guanine), C (cytosine), A (adenine) and T (thymine). This is the ...
s,
cryogenic In physics, cryogenics is the production and behaviour of materials at very low temperatures. The 13th IIR International Congress of Refrigeration (held in Washington DC in 1971) endorsed a universal definition of “cryogenics” and “cr ...
equipment,
thermal cycler The thermal cycler (also known as a thermocycler, PCR machine or DNA amplifier) is a laboratory apparatus most commonly used to amplify segments of DNA via the polymerase chain reaction (PCR). Thermal cyclers may also be used in laboratories to fa ...
s, etc.


National Centre for Laboratory Animal Sciences

The National Centre for Laboratory Animal Sciences (NCLAS) was established in India in 1957 for spreading knowledge on Care, Breeding, Management and Experimentation using laboratory animals in biomedical research. It started as a unit called Laboratory Animal Information Service (LAIS) at the Indian Cancer Research Centre, Bombay, in 1957 and this unit was later shifted to National Institute of Nutrition (NIN), Hyderabad in 1976. it was renamed then as Laboratory Animal Information Service Centre (LAISC). In 1998, during the 7th Five Year Plan, additional support came from Department of Biotechnology (DBT) under the Ministry of Science and Technology, Government of India, which helped the unit to become the NCLAS. On 5 January 2016, the NCLAS is merged with NARF-BR and the former Unit becomes the NIN-animal facility. The scientists of NCLAS Developed obese and diabetic mutant rat models: WNIN/GR-Ob, WNIN/Ob, WNIN/Ob-IGT, to serve as pre-clinical animal models in drug development for chronic diseases like Obesity and Diabetes. Established a state of the art non-human primate facility with provision for experiments based on monkeys. NCLAS also came into the limelight due to the WNIN/Ob obese rat strain which is the heaviest inbred rat model available. It has been reported to reach up to 1.47 kg in body weight and shows various signs of increased DNA damage and significantly decreased lifespan.


NIN and FSSAI

The
Food Safety and Standards Authority of India Food Safety and Standards Authority of India (FSSAI) is a statutory body established under the Ministry of Health & Family Welfare, Government of India. The FSSAI has been established under the Food Safety and Standards Act, 2006, which is a co ...
(FSSAI) largely sources science-based knowledge and information for formulating the food regulations in the country. Many scientists of NIN are a part of various committee, panels and scientific groups that guide the FSSAI. The Director is the co-Chair of the three member panel that is looking into upcoming the front-of-pack labelling regulations. The FSSAI is responsible for protecting and promoting
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
through the
regulation Regulation is the management of complex systems according to a set of rules and trends. In systems theory, these types of rules exist in various fields of biology and society, but the term has slightly different meanings according to context. For ...
and supervision of
food safety Food safety (or food hygiene) is used as a scientific method/discipline describing handling, preparation, and storage of food in ways that prevent food-borne illness. The occurrence of two or more cases of a similar illness resulting from t ...
. The FSSAI has been established under the Food Safety and Standards Act, 2006 which is a consolidating statute related to food safety and regulation in
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
.


Education

NIN offers advanced education courses and MS-MD-PhD program(s) for nutrition, biochemistry, dietetics and laboratory animal sciences. The Centre is recognised by
Dr. N.T.R. University of Health Sciences DR Y.S.R University of Health Sciences; DR.YSRUHS: ''Ḍā. En. Ṭī. Ār. Ārogyașāstra Vișvavidyālayamu'')is a public university in the city of Vijayawada, Andhra Pradesh, History The university was established as University of Health ...
and
Kaloji Narayana Rao University of Health Sciences Kaloji Narayana Rao University of Health Sciences (KNRUHS) is a public university in the city of Warangal, Telangana, India. University is named after its poet, and political activist of Telangana – Kaloji Narayana Rao. History Before the sta ...
for pursuing post graduation in Applied Nutrition. Recently NIN has started awarding Research Fellowships to the toppers in the MSc course to pursue PhD in the institution. The institute is well recognised by
Osmania University Osmania University is a collegiate public state university located in Hyderabad, Telangana, India. Mir Osman Ali Khan, the 7th Nizam of Hyderabad in 1918 , He released a farman to establish OSMANIA UNIVERSITY on the day of 28 August 1918. It ...
,
University of Hyderabad The University of Hyderabad (IAST: ''Hydarāvād visvavidyālayamu'') is a top ranking public central research university located in Hyderabad, Telangana, India. Founded in 1974, this mostly residential campus has more than 5,000 students a ...
,
Jawaharlal Nehru Technological University Jawaharlal Nehru Technological University may refer to: * Jawaharlal Nehru Technological University, Hyderabad * Jawaharlal Nehru Technological University, Kakinada * Jawaharlal Nehru Technological University, Anantapur * Jawaharlal Nehru Technolog ...
, for pursuing
PhD PHD or PhD may refer to: * Doctor of Philosophy (PhD), an academic qualification Entertainment * '' PhD: Phantasy Degree'', a Korean comic series * ''Piled Higher and Deeper'', a web comic * Ph.D. (band), a 1980s British group ** Ph.D. (Ph.D. albu ...
in various streams of Life Sciences especially
Biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...
and
Nutrition Nutrition is the biochemical and physiological process by which an organism uses food to support its life. It provides organisms with nutrients, which can be metabolized to create energy and chemical structures. Failure to obtain sufficient n ...
. The institute has trained over 1600 health professionals from more than 35 countries. More than 150 candidates have successfully obtained PhD and MD degrees from NIN.


Achievements

*Assessed dietary intake of individuals, house holds and nutritional profiles of different communities through periodic surveys of NNMB in 10 states. *Suggested strategies to identify high risk pregnancies in rural areas of India. These were included in the National Reproductive and Child Health Program. *Demonstrated ''TheraCyte'' Pancreatic Islet Transplantation technology in Primates and Rodents. *Commercially delivered double fortified Salt – Tata Salt Plus, priced at an economical rate of per kg, is an iodine plus iron fortified salt, developed by double fortification technology. This technology was offered to
Tata Chemicals Tata Chemicals Limited is an Indian global company with interests in chemicals, crop protection and specialty chemistry products headquartered in Mumbai, India. The company is one of the largest chemical companies in India with operations in In ...
under a long-term MoU after due studies on bio-availability across the population strata conducted and published by NIN. *Exploded the ''protein myth'' and highlighted ''calorie gap'' as the major bottleneck for healthy growth of children. *Developed simple and sensitive biochemical indicators for assessment of vitamin nutritive and pathogenic mechanisms of various nutritional deficiency syndromes. *Established growth norms for Indian children. *Emphasized the importance of growth monitoring for early diagnosis and appropriate management of protein energy malnutrition. *Generated database on nutritive values of over 650 Indian foods, which is used by various national organisations, planners and academic research institutions *Formulated Recommended Dietary Allowances (RDA) for Indians. *Developed food based Dietary Guidelines for Indians. *Developed National Nutrition Surveillance system (NSS-Triple ''A'' cycle of Assessment, Analysis and Action) to serve as an early warning system about nutrition problems.


See also

*
Genome Valley Genome Valley is an Indian high-technology business district spread across /(3.1 sq mi) in Hyderabad, India. It is located across the suburbs, Turakapally, Shamirpet, Medchal, Uppal, Patancheru, Jeedimetla, Gachibowli and Keesara. The Genome Va ...
*
National Animal Resource Facility for Biomedical Research The National Animal Resource Facility for Biomedical Research is an Indian Biomedical research facility, and vivarium under the Indian Council of Medical Research. The new 33rd flagship institute of ICMR was founded in 2015, at Genome Valley in ...
*
Central Drugs Standard Control Organization The Central Drugs Standard Control Organisation (CDSCO) is India's national regulatory body for cosmetics , pharmaceuticals and medical devices. It serves a similar function to the European Medicines Agency of the European Union, the PMDA of Jap ...


References


External links


Homepage of National Institute of Nutrition, Hyderabad, India
{{coord missing, Telangana Indian Council of Medical Research Research institutes in Hyderabad, India 1918 establishments in India Nutrition organizations Food and drink in India