The National Center for Integrative Biomedical Informatics (NCIBI) is one of seven
National Centers for Biomedical Computing funded by the
National Institutes of Health's (NIH) Roadmap for Medical Research. The center is based at the
University of Michigan and is part of the
Center for Computational Medicine and Bioinformatics. NCIBI's mission is to create targeted knowledge environments for molecular biomedical research to help guide experiments and enable new insights from the analysis of complex diseases. It was established in October 2005.
The Center develops computational methods to effectively access and integrate biological data. Driving Biological Projects (DBPs) provide a starting point from which tool development is informed, launched, and tested. Current DBPs include
gene fusion A fusion gene is a hybrid gene formed from two previously independent genes. It can occur as a result of translocation, interstitial deletion, or chromosomal inversion. Fusion genes have been found to be prevalent in all main types of human neoplas ...
in cancers, major organ-specific complications of
diabetes, nutrition and
obesity, and co-morbid disease associations of
bipolar disorder. In addition to testing tools for function, a separate team is dedicated to testing
usability
Usability can be described as the capacity of a system to provide a condition for its users to perform the tasks safely, effectively, and efficiently while enjoying the experience. In software engineering, usability is the degree to which a soft ...
and user interaction.
Once tools are developed and validated, the Center disseminates data and software throughout the University and the broader biomedical research community. Various mechanisms such as training videos, tutorials, and demonstrations and presentations at prominent scientific conferences are used to share NCIBI data and software nationally and internationally.
Available tools
In addition to the tools listed below, the enriched data contained in many NCIBI databases is available from the Databases tab on the Try Our Tools page.
NCIBI Try Our Tools page
/ref>
Exploratory analysis
Conceptual literature searching
See also
*Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
* Biomedical Informatics
Notes
References
*
External links
National Center for Integrative Biomedical Informatics homepageCytoscape
{{authority control
Genomics
Proteomics
Research institutes in Michigan
Medical research institutes in the United States
Bioinformatics organizations
National Institutes of Health
Medical and health organizations based in Michigan