Nancy L. Allbritton
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Nancy Allbritton is a Professor of Bioengineering and the Frank & Julie Jungers Dean of the College of Engineering at the University of Washington. She was previously a Kenan Professor and Chair in the Joint Department of Biomedical Engineering at the University of North Carolina at Chapel Hill and
North Carolina State University North Carolina State University (NC State) is a public land-grant research university in Raleigh, North Carolina. Founded in 1887 and part of the University of North Carolina system, it is the largest university in the Carolinas. The universit ...
. She is best known for her work in single-cell analysis. Using engineering methods, Allbritton creates tools for better understanding and manipulating living cells and tissues. Microengineered platforms, microfluidics, and novel biochemical assays enable scientists to study cell signaling and
signal transduction Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellula ...
at the single-cell level.


Education

Allbritton received a bachelor of science with a major in physics from Louisiana State University, Baton Rouge in 1979. She received a doctor of medicine from Johns Hopkins University in 1985 and a doctor of philosophy in medical physics and medical engineering from the Massachusetts Institute of Technology in 1987.


Career

Allbritton was a
postdoctoral fellow A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to p ...
at
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is consider ...
from 1989 to 1994. She then became a Professor at the University of California at Irvine, teaching in the departments of Physiology and Biophysics, Biomedical Engineering, Chemistry, Chemical Engineering and Materials Science. She remained at UC Irvine for 13 years, from 1994-2007. In 2007 Allbritton joined the University of North Carolina at Chapel Hill, becoming a Kenan Distinguished Professor. From 2009-2019 she was the Chair of the Joint Department of Biomedical Engineering at the University of North Carolina at Chapel Hill and
North Carolina State University North Carolina State University (NC State) is a public land-grant research university in Raleigh, North Carolina. Founded in 1887 and part of the University of North Carolina system, it is the largest university in the Carolinas. The universit ...
. She has held faculty appointments in Chemistry, Pharmacology and Applied Physical Sciences at UNC, and in the Department of Materials Science and Engineering at NC State. As of November 1, 2019, Allbritton became a Professor of Bioengineering and the Frank & Julie Jungers Dean of Engineering at the University of Washington College of Engineering. Allbritton was appointed a co-
editor Editing is the process of selecting and preparing written, photographic, visual, audible, or cinematic material used by a person or an entity to convey a message or information. The editing process can involve correction, condensation, orga ...
of the '' Annual Review of Analytical Chemistry'' in 2021.


Research interests

Allbritton's interest in single-cell analysis have hinged on the use of capillary electrophoresis (CE) and microfabricated technologies. Through this work she has studied lipid signaling at the single-cell level, the isolation cytotoxic t-cells with specific properties, and the capture of colonic crypts. In the
organ-on-a-chip An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture, integrated circuit (chip) that simulates the activities, mechanics and physiological response of an entire organ or an organ system, a type of artificial organ. It constitu ...
field, Allbritton has used fabrication technologies from electronics and microfluidics to develop devices that effectively recreate the environment of both the small and large intestine. These include micro
total analysis system Total Analysis System (TAS) describes a device that automates and includes all necessary steps for chemical analysis of a sample e.g. sampling, sample transport, filtration, dilution, chemical reactions, separation and detection. µTAS A new t ...
s and microraft arrays. In the area of
dielectrophoresis Dielectrophoresis (DEP) is a phenomenon in which a force is exerted on a dielectric particle when it is subjected to a non-uniform electric field. This force does not require the particle to be charged. All particles exhibit dielectrophoretic ac ...
(DEP), Allbritton's lab works on the transfer of DEP-based systems out of laboratories and into clinical use.


Awards

* 1982-1985, Health Sciences and Technology Fellowship, Massachusetts Institute of Technology * 1995,
Searle Scholar Award The Searle Scholars Program is a career development award made annually to the 15 young US professionals in biomedical research and chemistry considered most promising. The award was established in 1980 by a donation from the Searle family, and is ...
*1995,
Beckman Young Investigator Award The Beckman Young Investigators Award was established by Mabel and Arnold Beckman in 1991, and is now administered by the Arnold and Mabel Beckman Foundation. The Beckman Young Investigator (BYI) Program is intended to provide research support to p ...
*2003-2004, Distinguished Mid-Career Faculty Award for Research, University of California, Irvine *2009, Mary K. and Velmer A. Fassel Award, Iowa State University * 2015, NIH Director’s Transformative Award, National Institutes of Health * 2016, Award in Chemical Instrumentation, ACS Division of Analytical Chemistry * 2017, Edward Kidder Graham Leadership Award, UNC * 2017, Innovator of the Year, UNC-Chapel Hill * 2020, Ralph N. Adams Award in Bioanalytical Chemistry,
Pittcon The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, referred to internationally as Pittcon, is a non-profit educational organization based in Pennsylvania that organizes an annual Conference and Exposition on laboratory sc ...
*2021, Pritzker Distinguished Lecture Award,
Biomedical Engineering Society BMES (the Biomedical Engineering Society) is the professional society for students, faculty, researcher and industry working in the broad area of biomedical engineering. BMES is the leading biomedical engineering society in the United States and was ...


Patents

*"Fast controllable laser lysis of cells for analysis" Nancy L. Allbritton, Christopher E. Sims, Michael W. Berns, Gavin D. Meredith, Tatiana B. Krasieva, Bruce J. Tromberg U.S. Patent No. US6156576A *"Method and apparatus for detecting enzymatic activity using molecules that change electrophoretic mobility" Nancy L. Allbritton, Christopher E. Sims, Michael W. Berns, Gavin D. Meredith, Tatiana B. Krasieva, Bruce J. Tromberg U.S. Patent No. 6335201B1 *"Method to measure the activation state of signaling pathways in cells" Nancy Allbritton, Christopher Sims U.S. Patent No. 7236888B2 *"Chemical modifications to polymer surfaces and the application of polymer grafting to biomaterials" Nancy Allbritton, Christopher Sims, Guann-Pyng Li, Mark Bachman, Shuwen Hu, Xueqin Ren U.S. Patent No. 20050237480A1 *"Systems and methods for efficient collection of single cells and colonies of cells and fast generation of stable transfectants" Nancy Allbritton, Christopher E. Sims, Yuli Wang, Mark Bachman, Guann-Pyng Li, Eric Stanbridge U.S. Patent No. 7759119B2 *"Method and device for cell selection and collection in an isolated culturing environment" Nancy Allbritton, Christopher Sims, Wei Xu U.S. Patent No. 20110294208A1 *"Array of micromolded structures for sorting adherent cells" Nancy Allbritton, Christopher Sims, Yuli Wang, Pavak Kirit Shah U.S. Patent No. 9068155B2


References


External links


Office of the Dean, University of WashingtonJoint Department of Biomedical EngineeringUniversity of North Carolina at Chapel HillNorth Carolina State University
{{DEFAULTSORT:Allbritton, Nancy Living people American women biologists American biomedical engineers 20th-century American engineers 20th-century American women scientists 21st-century American scientists 21st-century American women scientists MIT School of Engineering alumni Year of birth missing (living people) 21st-century American women academics 21st-century American academics Annual Reviews (publisher) editors University of North Carolina at Chapel Hill faculty Johns Hopkins School of Medicine alumni Louisiana State University alumni