Nucleoporin 188 (Nup188) is a protein that in humans is encoded by the ''NUP188''

gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...

Function

Transport of macromolecules between the cytoplasm and nucleus occurs through

nuclear pore A nuclear pore is a part of a large complex of proteins, known as a nuclear pore complex that spans the nuclear envelope, which is the double membrane surrounding the eukaryotic cell nucleus. There are approximately 1,000 nuclear pore complexes ...

complexes (NPCs) embedded in the

nuclear envelope The nuclear envelope, also known as the nuclear membrane, is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which encloses the genetic material. The nuclear envelope consists of two lipid bilayer membrane ...

. NPCs are composed of subcomplexes, and NUP188 is part of one such subcomplex.

References

External links

* Nuclear pore complex {{gene-9-stub