Myron Essex
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Myron Elmer "Max" Essex (born August 17, 1939) is the
Mary Woodard Lasker Mary Woodard Lasker (November 30, 1900February 21, 1994) was an American health activist and philanthropist. She worked to raise funds for medical research and founded the Lasker Foundation. Early life Mary Woodard was born in Watertown, Wisconsi ...
Professor of Health Sciences, emeritus in the Department of Immunology and Infectious Diseases at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of high ...
, Chair of the
Harvard T.H. Chan School of Public Health The Harvard T.H. Chan School of Public Health is the public health school of Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. The school grew out of the Harvard-MIT School for Health Officers, the nation's first ...
AIDS Initiative (HAI) in the Department of Immunology and Infectious Diseases, and Chair of the Botswana–Harvard AIDS Institute in
Gaborone Gaborone ( , , ) is the capital and largest city of Botswana with a population of 246,325 based on the 2022 census, about 10% of the total population of Botswana. Its agglomeration is home to 421,907 inhabitants at the 2011 census. Gaboron ...
,
Botswana Botswana (, ), officially the Republic of Botswana ( tn, Lefatshe la Botswana, label= Setswana, ), is a landlocked country in Southern Africa. Botswana is topographically flat, with approximately 70 percent of its territory being the Kalaha ...
. Essex was one of the first to link animal and human retroviruses to
immunosuppressive Immunosuppression is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reacti ...
disease, to suspect that a retrovirus was the cause of AIDS, and to determine that
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
could be transmitted through blood and blood products to hemophiliacs and recipients of blood transfusions. With collaborators, Essex also provided the first evidence that HIV could be transmitted by
heterosexual Heterosexuality is romantic attraction, sexual attraction or sexual behavior between people of the opposite sex or gender. As a sexual orientation, heterosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions" ...
intercourse. In 1984, Essex identified
gp120 Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. It was discovered by Professors Tun-Hou Lee and Myron "Max" Essex of the Harvard School of Public Health in 1988. The 120 in its name comes from ...
, the virus surface protein that is used worldwide for blood screening, HIV detection, and epidemiological monitoring. With collaborators, including African microbiologist
Souleymane Mboup Souleymane Mboup (born 1951) is a Senegalese microbiologist, medical researcher, and colonel in the Armed Forces of Senegal. In 1985, he was a member of the first team to identify HIV-2, a form of HIV that is typically found in West Africa and ...
, he discovered the first
simian immunodeficiency virus ''Simian immunodeficiency virus'' (''SIV'') is a species of retrovirus that cause persistent infections in at least 45 species of non-human primates. Based on analysis of strains found in four species of monkeys from Bioko Island, which was iso ...
, as well as
HIV-2 The subtypes of HIV include two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in the sooty mangabe ...
. Since 1986, he has developed programs for AIDS collaboration in
Senegal Senegal,; Wolof: ''Senegaal''; Pulaar: 𞤅𞤫𞤲𞤫𞤺𞤢𞥄𞤤𞤭 (Senegaali); Arabic: السنغال ''As-Sinighal'') officially the Republic of Senegal,; Wolof: ''Réewum Senegaal''; Pulaar : 𞤈𞤫𞤲𞤣𞤢𞥄𞤲𞤣𞤭 ...
,
Thailand Thailand ( ), historically known as Siam () and officially the Kingdom of Thailand, is a country in Southeast Asia, located at the centre of the Indochinese Peninsula, spanning , with a population of almost 70 million. The country is b ...
,
Botswana Botswana (, ), officially the Republic of Botswana ( tn, Lefatshe la Botswana, label= Setswana, ), is a landlocked country in Southern Africa. Botswana is topographically flat, with approximately 70 percent of its territory being the Kalaha ...
,
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
,
Mexico Mexico (Spanish: México), officially the United Mexican States, is a country in the southern portion of North America. It is bordered to the north by the United States; to the south and west by the Pacific Ocean; to the southeast by Guatema ...
, and China. In 1996, Essex helped establish the Botswana–Harvard Partnership for HIV Research and Education (now the Botswana–Harvard AIDS Institute). This is a collaboration between the Ministry of Health in Botswana and HAI.


Biography

Essex was born in
Coventry, Rhode Island Coventry is a town in Kent County, Rhode Island, United States. The population was 35,688 at the 2020 census and is part of the . Geography According to the United States Census Bureau, the town has a total area of . of it is land and of it ...
in 1939. Essex earned his DVM from Michigan State University in 1967. He earned his Ph.D. from
University of California, Davis The University of California, Davis (UC Davis, UCD, or Davis) is a public land-grant research university near Davis, California. Named a Public Ivy, it is the northernmost of the ten campuses of the University of California system. The inst ...
, in 1970. He has been married to Elizabeth Essex since 1967. They have two daughters and five grandchildren.Henry MS. Max Essex: The Persistent Investigator. March 11, 2016. HAI Blog. Spotlight, Winter 2016.
/ref> Essex holds ten
honorary doctorate An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad hon ...
s and 15 patents and has received the
Lasker Award The Lasker Awards have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine. They are administered by the Lasker Foundation, which was ...
, the highest medical research award given in the United States, jointly with
Robert Gallo Robert Charles Gallo (; born March 23, 1937) is an American biomedical researcher. He is best known for his role in establishing the human immunodeficiency virus (HIV) as the infectious agent responsible for acquired immune deficiency syndrome ...
and Luc Montagnier in 1986. He has published over 500 papers and 12 books, including two editions of ''AIDS in Africa'' (), and his latest, ''Saturday Is for Funerals'' (). Essex has worked in twelve (12) different nations as a
veterinarian A veterinarian (vet), also known as a veterinary surgeon or veterinary physician, is a medical professional who practices veterinary medicine. They manage a wide range of health conditions and injuries in non-human animals. Along with this, vet ...
and
virologist Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, thei ...
: Botswana, China, Colombia, India, Japan, Nigeria, Senegal, Taiwan, Tanzania, Thailand, U.S., Zaire. His 45 years of working papers, the Myron Essex papers, 1949–1996, are archived in the Countway Library's Center for the History of Medicine through funding by a Hidden Collections grant from the
Harvard University Library Harvard Library is the umbrella organization for Harvard University's libraries and services. It is the oldest library system in the United States and both the largest academic library and largest private library in the world. Its collection ...
(HUL) within The Maximizing Microbiology: Molecular Genetics, Cancer, and Virology, 1936-2000 project. In addition to the Myron Essex papers (1949–1996), the project has already led to the processing of collections of several other microbiologists, including those of Bernard D. Davis, Arthur B. Pardee, Francesc Duran i Reynals, and Luigi Gorini. Essex serves on the Library's Archives Committee. He has been the primary mentor to eight (80) Postdocs and to 34 Doctoral students. He has authored 629 research papers, forty (40) of which have been published in Science or Nature. His 45 years of working papers, the Myron Essex papers, 1949–1996, are archived in the Countway Library's Center for the History of Medicine through funding by a Hidden Collections grant from the
Harvard University Library Harvard Library is the umbrella organization for Harvard University's libraries and services. It is the oldest library system in the United States and both the largest academic library and largest private library in the world. Its collection ...
(HUL) within The Maximizing Microbiology: Molecular Genetics, Cancer, and Virology, 1936-2000 project. In addition to the Myron Essex papers (1949–1996), the project has already led to the processing of collections of several other microbiologists, including those of Bernard D. Davis, Arthur B. Pardee, Francesc Duran i Reynals, and Luigi Gorini. Essex serves on the Library's Archives Committee. In 2018 Dr. Essex announced his retirement plans.


Awards

* Elected member, Institute of Medicine (IOM) of the National Academy of Sciences (NAS, now NASEM) * Fellow, American Academy of Microbiology * HIV Lifetime Achievement Award for Scientific Contributions from the Institute of Human Virology (IHV) at the University of Maryland School of Medicine, November 2011Henry MS. Essex Receives Lifetime Achievement Award. December 1, 2011. HAI Blog
/ref> * Lifetime Achievement Award, AIDS Society of India, 2014 (in Kolkata). The plaque reads “For his exemplary contribution towards research in HIV/AIDS and for his outstanding leadership in public health.”


Awards named for Max Essex

* Essex Fellowship for Students from Africa,
Harvard T.H. Chan School of Public Health The Harvard T.H. Chan School of Public Health is the public health school of Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. The school grew out of the Harvard-MIT School for Health Officers, the nation's first ...
, annually since 2007


References


External links


Harvard T.H. Chan School of Public Health faculty page for Myron 'Max' Essex, DVM
''Science Watch'', May 1993

''Harvard Public Health Review'', Spring/Summer 2011
Harvard T.H. Chan School of Public Health AIDS Initiative list of Associated ResearchersAnnouncement of 1988 founding of HAI, the Harvard AIDS Institute
- "Bok named Myron (Max) Essex, a virologist at the Harvard School of Public Health (HSPH), to lead the Institute. According to Essex, “HAI was the brainchild of Harvey Fineberg,” who was HSPH Dean at the time."
Harvard Catalyst Profile Page for Max EssexHarvard AIDS Institute Profile Page for Max EssexCoup E. Processing of the Myron “Max” Essex papers has begun. March 2, 2016. Website of Center for the History of Medicine at Countway Library.

Myron Essex Papers, 1949-1996 (inclusive), 1965-1996 (bulk). H MS c466. Harvard Medical Library, Francis A. Countway Library of Medicine, Boston, Mass.
{{DEFAULTSORT:Essex, Max American virologists Living people American public health doctors Michigan State University alumni University of California, Davis alumni 1939 births HIV/AIDS researchers Recipients of the Lasker-DeBakey Clinical Medical Research Award American veterinarians Male veterinarians Harvard School of Public Health faculty Botswana–United States relations 20th-century scientists 21st-century scientists