Myelodysplastic–myeloproliferative diseases
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Myelodysplastic–myeloproliferative diseases are a category of hematological malignancies which have characteristics of both
myelodysplastic A myelodysplastic syndrome (MDS) is one of a group of cancers in which immature blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. Early on, no symptoms typically are seen. Later, symptoms may ...
and
myeloproliferative Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. ''Myelo'' refers to the bone marrow, ''proliferative'' describes the rapid gr ...
conditions. When a
hematological malignancy Tumors of the hematopoietic and lymphoid tissues (American English) or tumours of the haematopoietic and lymphoid tissues (British English) are tumors that affect the blood, bone marrow, lymph, and lymphatic system. Because these tissues are all ...
is characterised by normal differentiation of cells of myeloid cell line, it is referred to as
myeloproliferative Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. ''Myelo'' refers to the bone marrow, ''proliferative'' describes the rapid gr ...
. On the other hand, when there is abnormal differentiation of cells of
myeloid cell A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow (can be found in circulating blood when caused by certain diseases). Structure When stained with the usual dyes, the cytoplasm is distinctly basophili ...
line, it is referred to as
myelodysplastic A myelodysplastic syndrome (MDS) is one of a group of cancers in which immature blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. Early on, no symptoms typically are seen. Later, symptoms may ...
.


References


External links

* http://www.cancer.gov/cancertopics/pdq/treatment/mds-mpd/Patient Myeloid neoplasia {{oncology-stub