Matrilins are
proteoglycan
Proteoglycans are proteins that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein" with one or more covalently attached glycosaminoglycan (GAG) chain(s). The point of attachment is a serine (Ser) residue to whic ...
-associated
proteins
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that are major components of
extracellular matrix
In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide stru ...
of various tissues. They include:
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Matrilin-1
Matrilin 1, cartilage matrix protein, also known as MATN1, is a matrilin protein which in humans is encoded by the ''MATN1'' gene.
Function
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of p ...
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Matrilin-2
Matrilin-2 is a matrilin protein that in humans is encoded by the ''MATN2'' gene.
This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of f ...
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Matrilin-3
Matrilin-3 is a matrilin protein that in humans is encoded by the ''MATN3'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''bir ...
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Matrilin-4
Extracellular matrix proteins
{{Protein-stub