Marcia Angell
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Marcia Angell (; born April 20, 1939) is an American physician, author, and the first woman to serve as editor-in-chief of the ''
New England Journal of Medicine ''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. Hist ...
''. She is currently a Senior Lecturer in the Department of Global Health and Social Medicine at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
in Boston, Massachusetts.


Biography

After completing undergraduate studies in chemistry and mathematics at
James Madison University James Madison University (JMU, Madison, or James Madison) is a public research university in Harrisonburg, Virginia. Founded in 1908 as the State Normal and Industrial School for Women at Harrisonburg, the institution was renamed Madison Coll ...
in
Harrisonburg, Virginia Harrisonburg is an independent city in the Shenandoah Valley region of the Commonwealth of Virginia in the United States. It is also the county seat of the surrounding Rockingham County, although the two are separate jurisdictions. At the 2 ...
, Angell spent a year as a
Fulbright Scholar The Fulbright Program, including the Fulbright–Hays Program, is one of several United States Cultural Exchange Programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of ...
studying microbiology in
Frankfurt, Germany Frankfurt, officially Frankfurt am Main (; Hessian: , "Frank ford on the Main"), is the most populous city in the German state of Hesse. Its 791,000 inhabitants as of 2022 make it the fifth-most populous city in Germany. Located on its na ...
. After receiving her M.D. from
Boston University School of Medicine The Boston University Chobanian & Avedisian School of Medicine, formerly the Boston University School of Medicine, is one of the graduate schools of Boston University. Founded in 1848, the medical school was the first institution in the world ...
in 1967, Angell trained in both internal medicine and anatomic
pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...
and is a
board-certified Board certification is the process by which a physician or other professional demonstrates a mastery of advanced knowledge and skills through written, practical, or simulator-based testing. Certification bodies There are more than 25 boards that ...
pathologist Pathology is the study of the causal, causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when us ...
. Angell is a frequent contributor to both medical journals and the popular media on a wide range of topics, particularly medical ethics, health policy, the nature of medical evidence, the interface of medicine and the law, and end-of-life healthcare. Her book, ''Science on Trial: The Clash of Medical Evidence and the Law in the Breast Implant Case'' (1996) received critical acclaim. With Stanley Robbins and, later, Vinay Kumar, she coauthored the first three editions of the textbook ''Basic Pathology''. She has written chapters in several books dealing with ethical issues in medicine and healthcare. Angell is a member of the
Association of American Physicians The Association of American Physicians (AAP) is an honorary medical society founded in 1885 by the Canadian physician Sir William Osler and six other distinguished physicians of his era for "the advancement of scientific and practical medicine." ...
, the
Institute of Medicine The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, E ...
of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
, the
Alpha Omega Alpha Alpha Omega Alpha Honor Medical Society () is an honor society in the field of medicine. Alpha Omega Alpha currently has active Chapters in 132 LCME- accredited medical schools in the United States and Lebanon. It annually elects over 4,000 new ...
National Honor Medical Society, and is a Master of the
American College of Physicians The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest ...
. She is also a fellow of the
Committee for the Scientific Investigation of Claims of the Paranormal The Committee for Skeptical Inquiry (CSI), formerly known as the Committee for the Scientific Investigation of Claims of the Paranormal (CSICOP), is a program within the US non-profit organization Center for Inquiry (CFI), which seeks to "prom ...
and is an outspoken critic of medical
quackery Quackery, often synonymous with health fraud, is the promotion of fraudulent or ignorant medical practices. A quack is a "fraudulent or ignorant pretender to medical skill" or "a person who pretends, professionally or publicly, to have skill, ...
and the promotion of
alternative medicine Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alt ...
.


''New England Journal of Medicine'' tenure

Angell joined the editorial staff of ''The New England Journal of Medicine'' (NEJM) in 1979. She became Executive Editor in 1988, and served as interim Editor-in-Chief from 1999 until June 2000. The NEJM is the oldest continuously published medical journal, and one of the most prestigious; Angell is the first woman to have served as Editor-in-Chief of the journal since it was founded in 1812. In 1999,
Jerome P. Kassirer Jerome P. Kassirer (born 1932 in Buffalo, New York, Buffalo, New York (state), New York) is an American nephrologist, medical researcher, and professor at Tufts University School of Medicine. He was the editor-in-chief of the ''New England Journal ...
, M.D. resigned as NEJM's Editor-in-Chief following a dispute with the journal's publisher, the
Massachusetts Medical Society The Massachusetts Medical Society (MMS) is the oldest continuously operating state medical association in the United States. Incorporated on November 1, 1781, by an act of the Massachusetts General Court, the MMS is a non-profit organization th ...
, over the Society's plan to use the journal's name to brand and market other sources of healthcare information. Angell agreed to serve as interim Editor-in-Chief until a permanent editor would be chosen. She reached an agreement with the society that the Editor-in-Chief would have authority over usage of the journal's name and logo, and that the journal's name would not be used on other products. Angell was a finalist for the permanent post of Editor-in-Chief, but withdrew as a candidate explaining she was retiring to write a book on alternative medicine. Angell retired from the journal in June 2000 and was replaced by
Jeffrey Drazen Jeffrey M. Drazen was the editor-in-chief of ''The New England Journal of Medicine'' from 2000 to 2019. He currently holds the positions of senior physician at the Brigham and Women’s Hospital, Distinguished Parker B. Francis Professor of Medicine ...
, M.D.


Positions


Criticism of conflicts of interest and biases in the medical establishment

In her 2009 article "Drug Companies & Doctors: A Story of Corruption", published in ''
The New York Review of Books ''The New York Review of Books'' (or ''NYREV'' or ''NYRB'') is a semi-monthly magazine with articles on literature, culture, economics, science and current affairs. Published in New York City, it is inspired by the idea that the discussion of i ...
'' magazine, Angell wrote :


Criticism of the Food and Drug Administration

Commenting on the 1992
Prescription Drug User Fee Act The ''Prescription Drug User Fee Act'' (PDUFA) was a law passed by the United States Congress in 1992 which allowed the Food and Drug Administration (FDA) to collect fees from Pharmaceutical company, drug manufacturers to fund the new medication, ...
which allowed the
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
(FDA) to collect fees from drug manufacturers to fund the new drug approval process, Angell has stated :


Criticism of U.S. healthcare system

Angell has long been a critic of the
U.S. healthcare system The United States far outspends any other nation on health care, measured both in ''per capita'' spending and as a percentage of GDP. Despite this, the country has significantly worse healthcare outcomes when compared to peer nations. The Uni ...
. The American healthcare system is in serious crisis, she stated in a 2000
PBS The Public Broadcasting Service (PBS) is an American public broadcasting, public broadcaster and Non-commercial activity, non-commercial, Terrestrial television, free-to-air television network based in Arlington, Virginia. PBS is a publicly fu ...
special: "If we had set out to design the worst system that we could imagine, we couldn't have imagined one as bad as we have." In the PBS interview, she urges the nation to scrap its failing healthcare system and start over:


Criticism of the pharmaceutical industry

Angell is a critic of the
pharmaceutical industry The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients (or self-administered), with the aim to cure them, vaccinate them, or alleviate symptoms. ...
. With
Arnold S. Relman Arnold Seymour Relman (June 17, 1923 – June 17, 2014) — known as Bud Relman to intimates — was an American internist and professor of medicine and social medicine. He was editor of ''The New England Journal of Medicine'' (''NEJM'') from 1 ...
, she argues, "The few drugs that are truly innovative have usually been based on taxpayer-supported research done in nonprofit academic medical centers or at the National Institutes of Health. In fact, many drugs now sold by drug companies were licensed to them by academic medical centers or small biotechnology companies." The pharmaceutical industry estimates that each new drug costs them $800 million to develop and bring to market, but Angell and Relman estimate the cost to them is actually closer to $100 million. Angell is the author of ''The Truth About the Drug Companies: How They Deceive Us and What to Do About It''. In her 2004 article "The Truth About the Drug Companies", published in ''
The New York Review of Books ''The New York Review of Books'' (or ''NYREV'' or ''NYRB'') is a semi-monthly magazine with articles on literature, culture, economics, science and current affairs. Published in New York City, it is inspired by the idea that the discussion of i ...
'', Angell wrote : Richard Friedman, director of the psychopharmacology clinic at Weill Cornell Medical College, and a regular contributor to the New York Times science pages, criticized Angell's views as unbalanced. "Dr. Angell is now doing pretty much the same thing the industry she assails has done, just the converse. Pharma withheld the bad news about its drugs and touted the positive results; Dr. Angell ignores positive data that conflicts with her cherished theory and reports the negative results.”


Views on alternative medicine

Marcia Angell is also a critic of the current categorization of
alternative medicine Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alt ...
. In a 1998 NEJM editorial she wrote with Jerome Kassirer, they argued: : It is time for the scientific community to stop giving alternative medicine a free ride. There cannot be two kinds of medicine — conventional and alternative. There is only medicine that has been adequately tested and medicine that has not, medicine that works and medicine that may or may not work. Once a treatment has been tested rigorously, it no longer matters whether it was considered alternative at the outset. If it is found to be reasonably safe and effective, it will be accepted.


Awards and honors

In 1997, ''
Time magazine ''Time'' (stylized in all caps) is an American news magazine based in New York City. For nearly a century, it was published weekly, but starting in March 2020 it transitioned to every other week. It was first published in New York City on Mar ...
'' named Marcia Angell one of the 25 most influential Americans for that year.


Works

*''Basic Pathology'' 1st edition (1971, Robbins, Stanley Leonard; Angell, Marcia); 2nd ed. (1973, Robbins, S.L.; Angell, M.); 3rd ed. (1981, Robbins, S.L.; Angell, M. Kumar, Vinay) * *


References


External links

* * * *
Quotes by Marcia Angell

Angell article archive
from ''
The New York Review of Books ''The New York Review of Books'' (or ''NYREV'' or ''NYRB'') is a semi-monthly magazine with articles on literature, culture, economics, science and current affairs. Published in New York City, it is inspired by the idea that the discussion of i ...
'' * {{DEFAULTSORT:Angell, Marcia Physicians from Massachusetts Harvard Medical School faculty American medical writers Women medical writers James Madison University alumni Boston University School of Medicine alumni 1939 births Living people The New England Journal of Medicine people American skeptics Critics of alternative medicine People from Knoxville, Tennessee American women physicians Medical journal editors American women academics 21st-century American women Members of the National Academy of Medicine