MIS12
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Protein MIS12 homolog is a
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''MIS12''
gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.


Interactions

MIS12 has been shown to
interact Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with
NSL1 Kinetochore-associated protein NSL1 homolog is a protein that in humans is encoded by the ''NSL1'' gene. This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that atta ...
,
ZWINT ZW10 interactor (Zwint-1) is a protein that in humans is encoded by the ''ZWINT'' gene. Function Zwint-1 is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, pos ...
,
CASC5 KNL1 (kinetochore scaffold 1, aka CASC5) is a protein that is encoded by the ''KNL1'' gene in humans. Function KNL1 is part of the outer kinetochore. It is a part of KMN network of proteins together with MIS12, and NDC80. KNL1 is involved in m ...
,
Polyamine-modulated factor 1 Polyamine-modulated factor 1 is a protein that in humans is encoded by the ''PMF1'' gene. Interactions Polyamine-modulated factor 1 has been shown to interact with MIS12 Protein MIS12 homolog is a protein that in humans is encoded by the ''M ...
,
NDC80 Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the ''NDC80'' gene. Function Ndc80 is one of the proteins of outer kinetochore. It forms a heterotetramer with proteins NUF2, SPC25, and SPC24. This protein complex has ...
,
DSN1 DSN1, MIND kinetochore complex component, homolog (S. cerevisiae), also known as DSN1 or MIS13, is a protein which in humans encoded by the ''DSN1'' gene. Function DSN1 along with MIS12, DC8, PMF1, CBX5, ZWINT is a component of the kinetochore- ...
and CBX5.


References


Further reading

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