''Mycobacterium lentiflavum''
Etymology: Lentus from Latin for slow, flavus, Latin for yellow.

Description

coccobacilli A coccobacillus (plural coccobacilli), or bacilluscocco, is a type of bacterium with a shape intermediate between cocci (spherical bacteria) and bacilli (rod-shaped bacteria). Coccobacilli, then, are very short rods which may be mistaken for cocci ...

. Colony characteristics *Smooth colonies, with bright yellow pigmentation 1-2mm in diameter. Physiology *Slow growth on Löwenstein-Jensen medium at temperatures between 22 °C and 37 °C within 3–4 weeks. *Generally resistant to isoniazid, rifampin, ethambutol and streptomycin. Differential characteristics *Phylogenetic analysis, based on an evaluation of

16S rDNA 16 S ribosomal RNA (or 16 S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence and provides most of the SSU structure. The genes coding for it are referred to as 16S rR ...

sequences, places M. lentiflavum in an intermediate position between rapidly and slowly growing

mycobacteria ''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis ('' M. tuberculosis'') and ...

, closely related to ''

Mycobacterium simiae ''Mycobacterium simiae'' is a species of ''Mycobacterium''.As per Runyon's classification it is classified as a photochromogen as it produces pigments only when exposed to light. References External links Type strain of ''Mycobacterium simia ...

'' and ''

Mycobacterium genavense Mycobacterium genavense is a slow-growing species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus ''Mycobacterium''. Description N ...

''.

Pathogenesis

*In young children with cervical lymphadenitis and in immunocompromised patientsMolteni C, Gazzola L, Cesari M, Lombardi A, Salerno F, Tortoli E, et al
Mycobacterium lentiflavum infection in immunocompetent patient.

Emerg Infect Dis ''Emerging Infectious Diseases'' (EID) is an open-access, peer-reviewed journal published by the Centers for Disease Control and Prevention (CDC). EID is a public domain journal and covers global instances of new and reemerging infectious disea ...

. 2005 Jan. *One case of vertebral osteomyelitis reported * Biosafety level 2

Type strain

*First isolated from a patient with

spondylodiscitis Spondylodiscitis is a combination of discitis (inflammation of one or more intervertebral disc spaces) and spondylitis (inflammation of one or more vertebrae), the latter generally involving the areas adjacent to the intervertebral disc space. C ...

(vertebral osteomyelitis). Further isolates from clinical specimens were obtained due to the use of contaminated bronchoscopes. Also recovered from

gastric juice Gastric acid, gastric juice, or stomach acid is a digestive fluid formed within the stomach lining. With a pH between 1 and 3, gastric acid plays a key role in digestion of proteins by activating digestive enzymes, which together break down the ...

sputum Sputum is mucus that is coughed up from the lower airways (the trachea and bronchi). In medicine, sputum samples are usually used for a naked eye examination, microbiological investigation of respiratory infections and cytological investigations ...

and urine samples. Strain 2186/92 = ATCC 51985 = CCUG 42422 = CCUG 42559 = CIP 105465 = DSM 44418 = JCM 13390.

References

*Springer et al. 1996. Isolation and characterization of a unique group of slowly growing mycobacteria: description of Mycobacterium lentiflavum sp. nov. J. Clin. Microbiol. 34, 1100–1107.

External links

Type strain of ''Mycobacterium lentiflavum'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Acid-fast bacilli lentiflavum Bacteria described in 1996 {{Mycobacterium-stub