Murray Sanders
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Murray Jonathan Sanders (April 11, 1910 - June 29, 1987) was an American
bacteriologist A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology -- a subdivision of microbiology that studies bacteria, typically Pathogenic bacteria, pathogenic ones. Bacteriologists are interested in studying and learnin ...
and military officer who was involved with the
U.S. Army The United States Army (USA) is the land service branch of the United States Armed Forces. It is one of the eight U.S. uniformed services, and is designated as the Army of the United States in the U.S. Constitution.Article II, section 2, cla ...
's
biological warfare Biological warfare, also known as germ warfare, is the use of biological toxins or infectious agents such as bacteria, viruses, insects, and fungi with the intent to kill, harm or incapacitate humans, animals or plants as an act of war. Bio ...
program during
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
. He is best known as the U.S. officer who convinced General
Douglas MacArthur Douglas MacArthur (26 January 18805 April 1964) was an American military leader who served as General of the Army for the United States, as well as a field marshal to the Philippine Army. He had served with distinction in World War I, was C ...
to grant legal immunity to members of the infamous Japanese
Unit 731 , short for Manshu Detachment 731 and also known as the Kamo Detachment and Ishii Unit, was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that engaged in lethal human experimentatio ...
chemical warfare Chemical warfare (CW) involves using the toxic properties of chemical substances as weapons. This type of warfare is distinct from nuclear warfare, biological warfare and radiological warfare, which together make up CBRN, the military acronym ...
research unit, despite the unit's practice of
unethical human experimentation Unethical human experimentation is human experimentation that violates the principles of medical ethics. Such practices have included denying patients the right to informed consent, using pseudoscientific frameworks such as race science, and tortu ...
.


Early life and education

Murray Sanders was born in
Chelsea, Massachusetts Chelsea is a city in Suffolk County, Massachusetts, Suffolk County, Massachusetts, United States, directly across the Mystic River from the city of Boston. As of the 2020 census, Chelsea had a population of 40,787. With a total area of just 2.46 s ...
on April 11, 1910. He studied
microbiology Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, prot ...
at
Rush Medical College Rush Medical College is the medical school of Rush University, located in the Illinois Medical District, about 3 km (2 miles) west of the Loop in Chicago. Offering a full-time Doctor of Medicine program, the school was chartered in 1837, and ...
in
Chicago (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...
, graduating in 1931 with an MD in the field. Sanders also received further training at
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
, eventually becoming a professor of microbiology there and engaging in
polio Poliomyelitis, commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 70% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe s ...
research.


Military service

Sanders was drafted into the army in 1943 and was stationed at
Fort Detrick Fort Detrick () is a United States Army Futures Command installation located in Frederick, Maryland. Historically, Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, i ...
, where he became involved with the army's research and development of
biological weapons A biological agent (also called bio-agent, biological threat agent, biological warfare agent, biological weapon, or bioweapon) is a bacterium, virus, protozoan, parasite, fungus, or toxin that can be used purposefully as a weapon in bioterrorism ...
. Sanders performed a number of classified investigations at Detrick, and proposed the use of weapons infused with
botulism Botulism is a rare and potentially fatal illness caused by a toxin produced by the bacterium ''Clostridium botulinum''. The disease begins with weakness, blurred vision, feeling tired, and trouble speaking. This may then be followed by weaknes ...
. He also warned that the
Japanese Empire The also known as the Japanese Empire or Imperial Japan, was a historical nation-state and great power that existed from the Meiji Restoration in 1868 until the enactment of the post-World War II 1947 constitution and subsequent forma ...
was planning to wage biological warfare on the United States through the dropping of
anthrax Anthrax is an infection caused by the bacterium ''Bacillus anthracis''. It can occur in four forms: skin, lungs, intestinal, and injection. Symptom onset occurs between one day and more than two months after the infection is contracted. The sk ...
-infused bombs on targets in the Pacific Coast.


Granting of immunity to Unit 731

Following the
surrender of Japan The surrender of the Empire of Japan in World War II was announced by Emperor Hirohito on 15 August and formally signed on 2 September 1945, bringing the war's hostilities to a close. By the end of July 1945, the Imperial Japanese Navy ...
and the Allied occupation that followed, Sanders was called upon by General
Douglas MacArthur Douglas MacArthur (26 January 18805 April 1964) was an American military leader who served as General of the Army for the United States, as well as a field marshal to the Philippine Army. He had served with distinction in World War I, was C ...
to head an investigation into Japan's biological warfare activity. Sanders traveled to Japan aboard the ship ''Sturgess'', arriving in
Yokohama is the second-largest city in Japan by population and the most populous municipality of Japan. It is the capital city and the most populous city in Kanagawa Prefecture, with a 2020 population of 3.8 million. It lies on Tokyo Bay, south of To ...
in September 1945. Sanders was assigned with the interrogation and interviewing of several Japanese scientists and military personnel involved with the
Imperial Japanese Army The was the official ground-based armed force of the Empire of Japan from 1868 to 1945. It was controlled by the Imperial Japanese Army General Staff Office and the Ministry of the Army, both of which were nominally subordinate to the Emperor o ...
's
chemical warfare Chemical warfare (CW) involves using the toxic properties of chemical substances as weapons. This type of warfare is distinct from nuclear warfare, biological warfare and radiological warfare, which together make up CBRN, the military acronym ...
research and development Research and development (R&D or R+D), known in Europe as research and technological development (RTD), is the set of innovative activities undertaken by corporations or governments in developing new services or products, and improving existi ...
unit,
Unit 731 , short for Manshu Detachment 731 and also known as the Kamo Detachment and Ishii Unit, was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that engaged in lethal human experimentatio ...
, which operated in
Harbin Harbin (; mnc, , v=Halbin; ) is a sub-provincial city and the provincial capital and the largest city of Heilongjiang province, People's Republic of China, as well as the second largest city by urban population after Shenyang and largest ...
,
Manchuria Manchuria is an exonym (derived from the endo demonym " Manchu") for a historical and geographic region in Northeast Asia encompassing the entirety of present-day Northeast China (Inner Manchuria) and parts of the Russian Far East (Outer Manc ...
and engaged in practices of illegal human experimentation from 1932 to 1945. Among those interviewed was bacteriologist Ryoichi Naito, who oversaw many of Unit 731's experiments, and also served as a translator for Sanders while interrogating the other interviewees. Initially, Naito and the other persons interviewed by Sanders denied any accusations of human experimentation, stating that the Japanese military had engaged solely in defensive research, and that experimenting on humans was "clearly against humanity". After Sanders threatened to hand those involved with Unit 731 over to the
Soviet Union The Soviet Union,. officially the Union of Soviet Socialist Republics. (USSR),. was a transcontinental country that spanned much of Eurasia from 1922 to 1991. A flagship communist state, it was nominally a federal union of fifteen national ...
, however, Naito agreed to send Sanders a manuscript which detailed their activities whilst headquartered at Harbin. After reviewing the data provided by those involved in Unit 731, Sanders presented the findings to MacArthur, stating that he believed the data to contain valuable information that must not end up in Soviet hands. Knowing that the physicians had fled their headquarters in order to avoid prosecution by the Soviets for war crimes, Sanders suggested that MacArthur grant the physicians involved
legal immunity Legal immunity, or immunity from prosecution, is a legal status wherein an individual or entity cannot be held liable for a violation of the law, in order to facilitate societal aims that outweigh the value of imposing liability in such cases. Su ...
against any war crimes charges in exchange for their data. MacArthur agreed with Sanders's proposal, believing the data “almost incalculable and incredibly valuable to the United States”, and agreed to grant the unit's physicians, including head scientist
Shirō Ishii Surgeon General was a Japanese microbiologist and army medical officer who served as the director of Unit 731, a biological warfare unit of the Imperial Japanese Army. Ishii led the development and application of biological weapons at Unit 73 ...
, immunity from prosecution as long as they exchanged their data with only the Americans. Following the acquittal, Sanders invited Ishii to Fort Detrick to lecture officers on the findings made by Unit 731. Sanders has been harshly criticized for his proposal to grant amnesty to Unit 731's members in spite of the atrocities they committed. He later testified before U.S. Congress regarding the failure of the
Tokyo War Crimes Tribunal The International Military Tribunal for the Far East (IMTFE), also known as the Tokyo Trial or the Tokyo War Crimes Tribunal, was a military trial convened on April 29, 1946 to try leaders of the Empire of Japan for crimes against peace, conven ...
to prosecute many Japanese war criminals. Sanders defended his decision in press interviews, stating that he had been "duped" and outsmarted by Naito and Ishii. Historian Sheldon Harris has also defended Sanders, calling him "ambitious but naïve", and claiming that he had "missed the trail leading to Ishii and others".


Civilian career

While in Japan, Sanders contracted a serious case of
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
, and was transferred back to Fort Detrick. He left the army in 1949 following his recovery and became Chairman of the Department of Medical Research at the
University of Miami The University of Miami (UM, UMiami, Miami, U of M, and The U) is a private research university in Coral Gables, Florida. , the university enrolled 19,096 students in 12 colleges and schools across nearly 350 academic majors and programs, incl ...
, a position which he held until 1958. He was among the founders of Miami's Variety Children's Hospital. During his time working at the University of Miami, Sanders proposed a potential treatment for amyotrophic lateral sclerosis (ALS) using what he called a "Modified Neurotoxin" (MNT) derived from the zootoxins in
snake venom Snake venom is a highly toxic saliva containing zootoxins that facilitates in the immobilization and digestion of prey. This also provides defense against threats. Snake venom is injected by unique fangs during a bite, whereas some species are a ...
. Although Sanders was nominated in 1966 for a
Nobel Prize in Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according ...
for his efforts, his treatment would later be criticized as ineffective by a number of physicians; a 1980 study by doctors Victor Rivera, Martin Grabois, and William Deaton found that Sanders's treatment had a "lack of clinical effectiveness" and "did not demonstrate any benefit from administration of modified snake venom to patients with ALS". Sanders opened the Sanders Medical Research Foundation (SMRF) in
Boca Raton, Florida Boca Raton ( ; es, Boca Ratón, link=no, ) is a city in Palm Beach County, Florida, United States. It was first incorporated on August 2, 1924, as "Bocaratone," and then incorporated as "Boca Raton" in 1925. The population was 97,422 in the ...
in 1973, in which he treated patients with ALS until his retirement from medical research in 1983. Sanders would also administer MNT treatment on test subjects in
Havana Havana (; Spanish: ''La Habana'' ) is the capital and largest city of Cuba. The heart of the La Habana Province, Havana is the country's main port and commercial center.
as a possible remedy for polio. Sanders was one of the first scientists to identify and experiment with
adenoviral keratoconjunctivitis Adenoviral keratoconjunctivitis, also known as epidemic keratoconjunctivitis, is a contagious eye infection, a type of adenovirus disease caused by ''adenoviruses''. It typically presents as a conjunctivitis with a sudden onset of a painful red e ...
, a
viral infection A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells. Structural Characteristics Basic structural characteristics, s ...
of the eye. As a result, the condition became informally known as Sanders disease; however, this terminology is no longer used by ophthalmologists. Sanders died on June 29, 1987, at his home in
Delray Beach, Florida Delray Beach is a city in Palm Beach County, Florida, Palm Beach County, Florida, United States. The population of Delray Beach as of April 1, 2020 was 66,846 according to the 2020 United States census, 2020 United States Census. Located 52 miles ...
, at the age of 77. He is buried at
Arlington National Cemetery Arlington National Cemetery is one of two national cemeteries run by the United States Army. Nearly 400,000 people are buried in its 639 acres (259 ha) in Arlington, Virginia. There are about 30 funerals conducted on weekdays and 7 held on Sa ...
.


References

{{Reflist 1910 births 1987 deaths