Multiple hamartoma syndrome is a

syndrome A syndrome is a set of medical signs and symptoms which are correlated with each other and often associated with a particular disease or disorder. The word derives from the Greek σύνδρομον, meaning "concurrence". When a syndrome is paired ...

characterized by more than one

hamartoma A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended fr ...

. It is sometimes equated with

Cowden syndrome Cowden syndrome (also known as Cowden's disease and multiple hamartoma syndrome) is an autosomal dominant inherited condition characterized by benign overgrowths called hamartomas as well as an increased lifetime risk of breast, thyroid, uterine, ...

. However,

MeSH A mesh is a barrier made of connected strands of metal, fiber, or other flexible or ductile materials. A mesh is similar to a web or a net in that it has many attached or woven strands. Types * A plastic mesh may be extruded, oriented, ex ...

also includes Bannayan–Zonana syndrome (that is,

Bannayan–Riley–Ruvalcaba syndrome Bannayan–Riley–Ruvalcaba syndrome (BRRS) is a rare overgrowth syndrome and hamartomatous disorder with occurrence of multiple subcutaneous lipomas, macrocephaly and hemangiomas. The disease is inherited in an autosomal dominant manner. The di ...

) and

Lhermitte–Duclos disease Lhermitte–Duclos disease (LDD) (), also called dysplastic gangliocytoma of the cerebellum, is a rare diseases, rare, slowly growing tumor of the cerebellum, a ganglioglioma, gangliocytoma sometimes considered to be a hamartoma, characterized by d ...

under this description. Some articles include Cowden syndrome, Bannayan–Riley–Ruvalcaba syndrome, and at least some forms of

Proteus syndrome Proteus syndrome is a rare disorder with a genetic background that can cause tissue overgrowth involving all three embryonic lineages. Patients with Proteus syndrome tend to have an increased risk of embryonic tumor development.Freedberg, et al. ...

and

Proteus-like syndrome Proteus-like syndrome (PLS) is a condition similar to Proteus syndrome, but with an uncertain cause.It's characterized by skeletal and hamartous overgrowth of multiple tissues, nevi in cerebriform connective tissue, blood vessel malformations and l ...

under the umbrella term PTEN hamartoma tumor syndromes (PHTS).

References

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Epidermal nevi, neoplasms, and cysts Syndromes affecting the skin {{epidermal-growth-stub

See also

References

External links