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The Multicenter AIDS Cohort Study (MACS) is an ongoing
cohort study A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing ...
involving over 6,000 men, including both those infected with
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
, as well as HIV-negative men. The MACS has four main sites: Baltimore, Pittsburgh, Los Angeles, and Chicago. The Los Angeles component of the MACS is called the Los Angeles Mens Study or LAMS. LAMS affiliated with UCLA and is supervised by Dr Roger Detels, MD & John Oishi. The study, a program of the Division of Acquired Immunodeficiency Syndrome, has been ongoing since 1984 and has resulted in over 1,000 scientific publications. It helped to establish that AIDS was the result of a viral illness and how HIV was spread. Participants were quizzed in detail about their sexual behavior. "They ask you for numbers, how many times did you do what." Some participants who had many sexual partners were not infected, and this led to the realization that some people had genetic resistance to the virus.


See also

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Clinical trial Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietar ...
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Women's Interagency HIV Study The Women's Interagency HIV Study (WIHS) was established in August 1993 to investigate the impact and progression of HIV disease in women. he WIHS enrolls both HIV-positive and HIV-negative women. The core portion of the study includes a detaile ...


References

HIV/AIDS Clinical trials related to HIV Cohort studies {{health-informatics-stub