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The morning glory disc anomaly (MGDA) is a congenital deformity resulting from failure of the 
On fundoscopic examination, there are three principal findings comprising the anomaly:
#an enlarged, funnel-shaped excavation in optic disc
#an annulus or ring of
optic nerve
In neuroanatomy, the optic nerve, also known as the second cranial nerve, cranial nerve II, or simply CN II, is a paired cranial nerve that transmits visual system, visual information from the retina to the brain. In humans, the optic nerve i ...
to completely form in utero. The term was coined in 1970 by Kindler, noting a resemblance of the malformed optic nerve to the morning glory
Morning glory (also written as morning-glory) is the common name for over 1,000 species of flowering plants in the family Convolvulaceae, whose current taxonomy and systematics are in flux. Morning glory species belong to many genera, some of ...
flower. The condition is usually unilateral.
Presentation
Complications
Serous retinal detachment can occur in the affected eye.Associated conditions
Although the finding itself is rare, MGDA can be associated with midline cranial defects and abnormalcarotid
In anatomy, the left and right common carotid arteries (carotids) (Entry "carotid"
in
stenosis A stenosis (from Ancient Greek στενός, "narrow") is an abnormal narrowing in a blood vessel or other tubular organ or structure such as foramina and canals. It is also sometimes called a stricture (as in urethral stricture). ''Stricture'' ...
/aplasia or progressive vascular obstruction with collateralization (also known as in
stenosis A stenosis (from Ancient Greek στενός, "narrow") is an abnormal narrowing in a blood vessel or other tubular organ or structure such as foramina and canals. It is also sometimes called a stricture (as in urethral stricture). ''Stricture'' ...
moyamoya disease
Moyamoya disease is a disease in which certain arteries in the brain are constricted. Blood flow is blocked by constriction and blood clots (thrombosis). A collateral circulation develops around the blocked vessels to compensate for the blockage, ...
). The vascular defects may lead to ischemia, stroke, or seizures and so a finding of MGDA should be further investigated with radiographic imaging.
Diagnosis
On fundoscopic examination, there are three principal findings comprising the anomaly:
#an enlarged, funnel-shaped excavation in optic disc
#an annulus or ring of chorioretinal
The choroid, also known as the choroidea or choroid coat, is a part of the uvea, the vascular layer of the eye, and contains connective tissues, and lies between the retina and the sclera. The human choroid is thickest at the far extreme rear ...
pigmentary changes surrounding the optic disc excavation
#a central glial tuft overlying the optic disc
See also
*Coloboma of optic nerve
Coloboma of optic nerve is a rare defect of the optic nerve that causes moderate to severe visual field defects.
Coloboma of the optic nerve is a congenital anomaly of the optic disc in which there is a defect of the inferior aspect of the opt ...
References
{{reflist Optic nerve Disorders of optic nerve and visual pathways