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Mohammad-Nabi Sarbolouki ( fa, محمدنبی سربلوکی) was a distinguished
Iran Iran, officially the Islamic Republic of Iran, and also called Persia, is a country located in Western Asia. It is bordered by Iraq and Turkey to the west, by Azerbaijan and Armenia to the northwest, by the Caspian Sea and Turkmeni ...
ian
biophysicist Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study Biology, biological phenomena. Biophysics covers all scales of biological organization, from Molecule, molecular to organismic ...
and
polymer A polymer (; Greek '' poly-'', "many" + ''-mer'', "part") is a substance or material consisting of very large molecules called macromolecules, composed of many repeating subunits. Due to their broad spectrum of properties, both synthetic a ...
chemist and one of the most influential individuals behind modern scientific movement in Iran. He was known as the inventor of a DNA vehicle called " dendrosome". Sarbolouki was one of the main founders and pioneers of nano science, biomaterials, biotechnology and biophysics in Iran. Sarbolouki studied chemistry at
Tehran University The University of Tehran (Tehran University or UT, fa, دانشگاه تهران) is the most prominent university located in Tehran, Iran. Based on its historical, socio-cultural, and political pedigree, as well as its research and teaching pro ...
and did his PhD in Macromolecular Physical Chemistry at Polytechnic University of New York. He then spent two years at
Michigan State University Michigan State University (Michigan State, MSU) is a public university, public Land-grant university, land-grant research university in East Lansing, Michigan. It was founded in 1855 as the Agricultural College of the State of Michigan, the fi ...
as a postdoctoral fellow. Sarbolouki then joined
NASA The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the civil space program, aeronautics research, and space research. NASA was established in 1958, succeeding t ...
where he worked as a group leader till 1981. Sarbolouki had numerous publications and patents on various subjects ranging from engineering to basic sciences. He initiated biomaterial research in Iran and was among the first to do structural biology in the country. He made significant contribution to the field of lipid bilayer membranes and
liposome A liposome is a small artificial vesicle, spherical in shape, having at least one lipid bilayer. Due to their hydrophobicity and/or hydrophilicity, biocompatibility, particle size and many other properties, liposomes can be used as drug deliver ...
s,
biodegradable polymer Biodegradable polymers are a special class of polymer that breaks down after its intended purpose by bacterial decomposition process to result in natural byproducts such as gases ( CO2, N2), water, biomass, and inorganic salts. These polymers ar ...
s,
tissue engineering Tissue engineering is a biomedical engineering discipline that uses a combination of Cell (biology), cells, engineering, Materials science, materials methods, and suitable biochemistry, biochemical and physicochemical factors to restore, maintai ...
, nanospheres (magnetic/fluorescent) and
drug delivery Drug delivery refers to approaches, formulations, manufacturing techniques, storage systems, and technologies involved in transporting a pharmaceutical compound to its target site to achieve a desired therapeutic effect. Principles related to d ...
. Sarbolouki was of the founding members of Iranian Society of Nanotechnology, Iranian Society of Proteomics and Iranian Chemical Society. He founded the first
Biomaterial A biomaterial is a substance that has been engineered to interact with biological systems for a medical purpose, either a therapeutic (treat, augment, repair, or replace a tissue function of the body) or a diagnostic one. As a science, biomateria ...
Research Center in Iran as well as National Research Center for Genetic Engineering and Biotechnology,
ICGEB The International Centre for Genetic Engineering and Biotechnology (ICGEB) was established as a project of the United Nations Industrial Development Organization (UNIDO) in 1983. The Organisation has three Component laboratories with over 45 ongo ...
headquarter in Iran. Sarbolouki was involved in science policy making at the national level and was instrumental in the advancement of interdisciplinary and applied research in Iran. Professor Sarbolouki was the editor of
Molecules A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...
, an international journal devoted to synthetic organic chemistry and natural product chemistry. He was also chief editor of Iranian Journal of Chemistry & Chemical Engineering. Professor Sarbolouki died on September 1, 2009 and his body was buried in Tehran Cemeteries, at the block for national legends on September 2, 2009. The Vice President and Minister of Science delivered messages of condolenceپیام تسلیت معاون رئیس جمهور به مناسبت درگذشت دکتر محمد نبی سربلوکی
/ref> and his burial was attended by numerous Iranian academics, scholars and students.


Awards and distinctions

*National Biotechnology Award, (2000) *Iranian Academy of Science, Associate member (1992–2008) *Iranian Academy of Literature, Associate member (2003–2008) *President, Institute of Biophysics and Biochemistry. *President, Biomaterial Research Center *Chairman, Faculty of Sciences, University of Tehran


Selected publications

*''Dendrosome:'' **Dendrosomes: a novel family of vehicles for transfection and therapy. Journal of Chemical Technology & Biotechnology. Volume 75 Issue 10, Pages 919 - 922 (2000) **Dendrosomes as novel gene porters-III. Journal of Chemical Technology & Biotechnology Volume 83 Issue 6, Pages 912 - 920 (2008) *''Structural biology:'' **Functional and structural characterization of a novel member of the natriuretic family of peptides from the venom of Pseudocerastes persicus. FEBS Letters Volume 557 Issue 1-3, Pages 104-108 (2004) **Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy. European Journal of Biochemistry Volume 271 Issue 23-24 Pages 4950-4957 (2004) *''Biomaterials: '' **Synthesis and thermal behavior of triblock copolymers from L-lactide and
ethylene glycol Ethylene glycol (IUPAC name: ethane-1,2-diol) is an organic compound (a vicinal diol) with the formula . It is mainly used for two purposes, as a raw material in the manufacture of polyester fibers and for antifreeze formulations. It is an odo ...
with long center PEG block. Journal of Applied Polymer Science Volume 68 Issue 12 Pages 1949-1954 (1998) **Synthesis and characterization of novel biodegradable triblock copolymers from L-lactide, glycolide, and PPG. Journal of Applied Polymer Science Volume 73 Issue 5 Pages 633-637 (1999) **Synthesis and characterization of ABA triblock and novel multiblock copolymers from ethylene glycol, L-lactide, and epsilon-caprolactone. Journal of Applied Polymer Science Volume 83 Issue 10 Pages 2072-2081 (2002) **Mass preparation and characterization of alginate microspheres. Process Biochemistry Volume 35 Issue 9 Pages 885-888 (2000) *''Membranes:'' **A simple method for preparation of immuno-magnetic liposomes. International Journal of Pharmaceutics Volume 215 Issue 1-2 Pages 45–50 (2001) *''Chromatography:'' **Separation and Indirect Detection of Amino-acids by Reversed Phase ion-pair Chromatography. Journal of Chromatographic Science Volume 31 Issue 11 Pages 480-485 (1993) **Determination of pore/protein size via electrophoresis and slit sieve model. Electrophoresis Volume 25 Issue 17 Pages 2907-2911 (2004)


See also

*
Science in Iran Iran has made considerable advances in science and technology through education and training, despite international sanctions in almost all aspects of research during the past 30 years. Iran's university population swelled from 100,000 in 1979 ...
*
Jet Propulsion Laboratory The Jet Propulsion Laboratory (JPL) is a federally funded research and development center and NASA field center in the City of La Cañada Flintridge, California, United States. Founded in the 1930s by Caltech researchers, JPL is owned by NASA an ...
*
Institute of Biochemistry and Biophysics The Institute of Biochemistry and Biophysics (IBB) is a pioneering Iranian research institute founded in 1976 to conduct world class research in cellular and molecular biology. It is affiliated with University of Tehran and is located in the uni ...


References

{{DEFAULTSORT:Sarbolouki, Mohammad-Nabi California Institute of Technology people Iranian biophysicists Iranian chemists 2009 deaths Michigan State University alumni NASA people Iranian physical chemists University of Tehran alumni Academic staff of the University of Tehran Year of birth missing