ModBase is a database of annotated
comparative protein structure models, containing models for more than 3.8 million unique protein sequences.
Models are created by the
comparative modeling
Homology modeling, also known as comparative modeling of protein, refers to constructing an atomic-resolution model of the "''target''" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous pr ...
pipeline
ModPipe which relies on the
MODELLER
Modeller, often stylized as MODELLER, is a computer program used for homology modeling to produce models of protein tertiary structures and quaternary structures (rarer). It implements a method inspired by nuclear magnetic resonance spectroscopy ...
program.
ModBase is developed in the laboratory of
Andrej Sali
Andrey, Andrej or Andrei (in Cyrillic script: Андрей, Андреј or Андрэй) is a form of Andreas/Ἀνδρέας in Slavic languages and Romanian. People with the name include:
*Andrei of Polotsk ( – 1399), Lithuanian nobleman
*An ...
at
UCSF
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It condu ...
. ModBase models are also accessible through the
Protein Model Portal
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respond ...
.
See also
*
Homology modeling
Homology modeling, also known as comparative modeling of protein, refers to constructing an atomic-resolution model of the "''target''" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous pr ...
References
External links
* http://salilab.org/modbase
Biological databases
Protein methods
Protein structure
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