The Mnt internal ribosome entry site (
IRES) is an
RNA element. Mnt is a transcriptional repressor related to the Myc/Mad family of
transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The fu ...
s. It is thought that this IRES allows efficient Mnt synthesis when cap-dependent translation initiation is reduced.
See also
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N-myc IRES
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Tobamovirus IRES
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TrkB IRES
The TrkB internal ribosome entry site (IRES) is an RNA element which is present in the 5' UTR sequence of the mRNA. TrkB is a neurotrophin receptor which is essential for the development and maintenance of the nervous system. The internal ribosom ...
References
External links
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Cis-regulatory RNA elements
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