Mixed Venous Oxygen Saturation
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Oxygen saturation (symbol SO2) is a relative measure of the concentration of
oxygen Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as wel ...
that is dissolved or carried in a given medium as a proportion of the maximal concentration that can be dissolved in that medium at the given temperature. It can be measured with a dissolved oxygen probe such as an
oxygen sensor An oxygen sensor (or lambda sensor, where lambda refers to air–fuel equivalence ratio, usually denoted by λ) or probe or sond, is an electronic device that measures the proportion of oxygen (O2) in the gas or liquid being analysed. It was ...
or an
optode An optode or optrode is an optical sensor device that optically measures a specific substance usually with the aid of a chemical transducer. Construction An optode requires three components to function: a chemical that responds to an analyte, a p ...
in liquid media, usually water. The standard unit of oxygen saturation is percent (%). Oxygen saturation can be measured regionally and noninvasively.
Arterial An artery (plural arteries) () is a blood vessel in humans and most animals that takes blood away from the heart to one or more parts of the body (tissues, lungs, brain etc.). Most arteries carry oxygenated blood; the two exceptions are the pul ...
oxygen saturation (SaO2) is commonly measured using
pulse oximetry Pulse oximetry is a noninvasive method for monitoring a person's oxygen saturation. Peripheral oxygen saturation (SpO2) readings are typically within 2% accuracy (within 4% accuracy in 95% of cases) of the more accurate (and invasive) reading of ...
. Tissue saturation at peripheral scale can be measured using NIRS. This technique can be applied on both muscle and brain.


In medicine

In
medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pract ...
, oxygen saturation refers to ''oxygenation'', or when oxygen molecules () enter the tissues of the body. In this case
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the c ...
is oxygenated in the
lung The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of t ...
s, where oxygen molecules travel from the air into the blood. Oxygen saturation (() sats) measures the percentage of
hemoglobin Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocyte ...
binding sites in the bloodstream occupied by oxygen. Fish, invertebrates, plants, and aerobic bacteria all require oxygen.


In environmental science

In aquatic environments, oxygen saturation is a ratio of the concentration of "dissolved
oxygen Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as wel ...
" (DO, O2), to the maximum amount of oxygen that will dissolve in that water body, at the temperature and pressure which constitute stable equilibrium conditions. Well-aerated water (such as a fast-moving stream) without oxygen producers or consumers is 100% saturated. It is possible for stagnant water to become somewhat
supersaturated In physical chemistry, supersaturation occurs with a solution when the concentration of a solute exceeds the concentration specified by the value of solubility at equilibrium. Most commonly the term is applied to a solution of a solid in a liqu ...
with oxygen (i.e. reach more than 100% saturation) either because of the presence of photosynthetic aquatic oxygen producers or because of a slow equilibration after a change of atmospheric conditions. Stagnant water in the presence of decaying matter will typically have an oxygen concentration much less than 100%, which is due to anaerobic bacteria being much less efficient at breaking down organic material. Similarly as in water, oxygen concentration also plays a key role in the breakdown of organic matter in soils. Higher oxygen saturation allows for aerobic bacteria to persist, which break down decaying organic material in soils much more efficiently than anaerobic bacteria. Thus soils with high oxygen saturation will have less organic matter per volume than those with low oxygen saturation. Environmental oxygenation can be important to the
sustainability Specific definitions of sustainability are difficult to agree on and have varied in the literature and over time. The concept of sustainability can be used to guide decisions at the global, national, and individual levels (e.g. sustainable livi ...
of a particular
ecosystem An ecosystem (or ecological system) consists of all the organisms and the physical environment with which they interact. These biotic and abiotic components are linked together through nutrient cycles and energy flows. Energy enters the syste ...
. The
US Environmental Protection Agency The Environmental Protection Agency (EPA) is an independent executive agency of the United States federal government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it be ...
has published a table of maximum equilibrium dissolved oxygen concentration versus temperature at atmospheric pressure. The optimal levels in an estuary for dissolved oxygen is higher than 6 ppm. Insufficient oxygen ( environmental hypoxia), often caused by the decomposition of organic matter and/or
nutrient pollution Nutrient pollution, a form of water pollution, refers to contamination by excessive inputs of nutrients. It is a primary cause of eutrophication of surface waters (lakes, rivers and coastal waters), in which excess nutrients, usually nitrogen or ...
, may occur in bodies of water such as
pond A pond is an area filled with water, either natural or artificial, that is smaller than a lake. Defining them to be less than in area, less than deep, and with less than 30% emergent vegetation helps in distinguishing their ecology from th ...
s and
river A river is a natural flowing watercourse, usually freshwater, flowing towards an ocean, sea, lake or another river. In some cases, a river flows into the ground and becomes dry at the end of its course without reaching another body of wate ...
s, tending to suppress the presence of
aerobic organism Aerobic means "requiring air," in which "air" usually means oxygen. Aerobic may also refer to * Aerobic exercise, prolonged exercise of moderate intensity * Aerobics, a form of aerobic exercise * Aerobic respiration, the aerobic process of cell ...
s such as
fish Fish are aquatic, craniate, gill-bearing animals that lack limbs with digits. Included in this definition are the living hagfish, lampreys, and cartilaginous and bony fish as well as various extinct related groups. Approximately 95% of li ...
. Deoxygenation increases the relative population of
anaerobic organism An anaerobic organism or anaerobe is any organism that does not require molecular oxygen for growth. It may react negatively or even die if free oxygen is present. In contrast, an aerobic organism (aerobe) is an organism that requires an oxygenate ...
s such as plants and some
bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
, resulting in
fish kill The term fish kill, known also as fish die-off, refers to a localized die-off of fish populations which may also be associated with more generalized mortality of aquatic life.University of Florida. Gainesville, FL (2005) ''Plant Management in Fl ...
s and other adverse events. The net effect is to alter the
balance of nature The balance of nature, also known as ecological balance, is a theory that proposes that ecological systems are usually in a stable equilibrium or homeostasis, which is to say that a small change (the size of a particular population, for example) w ...
by increasing the concentration of anaerobic over aerobic
species In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate s ...
.


See also

* Oxygen deficiency


References

{{Wastewater Aquatic ecology Blood Water quality indicators Oxygen