Mitiglinide (

INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...

, trade name Glufast) is a

drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...

for the treatment of

type 2 diabetes Type 2 diabetes, formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, ...

. Mitiglinide belongs to the

meglitinide Meglitinides or glinides are a class of drugs used to treat type 2 diabetes. Drugs Repaglinide (trade name Prandin) gained US Food and Drug Administration approval in 1997. Other drugs in this class include nateglinide (Starlix) and mitiglin ...

(glinide) class of blood glucose-lowering drugs and is currently co-marketed in Japan by

Kissei Kissei Pharmaceutical is a pharmaceutical company based in Matsumoto, Nagano, Japan. Products discovered or developed by Kissei include: * Difelikefalin * Fostamatinib (trade name Tavalisse) * Linzagolix * Mitiglinide (Glufast) * Remogliflozin etab ...

and

Takeda is a Japanese family name.1990 Census Name Files< ...

. The North America rights to mitiglinide are held by Elixir Pharmaceuticals. Mitiglinide has not yet gained

FDA The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...

approval.

Pharmacology

Mitiglinide is thought to stimulate

insulin Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the ''INS'' gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism o ...

secretion by closing the ATP-sensitive potassium K_ATP channels in pancreatic β cells.

Dosage

Mitiglinide is delivered in tablet form.

References

External links

Elixir Pharmaceuticals
— website of the U.S. rights holder for mitiglinide. {{Ion channel modulators Carboxamides Isoindoles Meglitinides Potassium channel blockers