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Missouri Constitutional Amendment 2 (The Missouri Stem Cell Research and Cures Initiative) was a state constitutional amendment initiative that concerned stem cell research and
human cloning Human cloning is the creation of a genetically identical copy (or clone) of a human. The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. It does not refer to the natural concepti ...
. It allows any stem cell research and therapy in the
U.S. state In the United States, a state is a constituent political entity, of which there are 50. Bound together in a political union, each state holds governmental jurisdiction over a separate and defined geographic territory where it shares its sove ...
of
Missouri Missouri is a state in the Midwestern region of the United States. Ranking 21st in land area, it is bordered by eight states (tied for the most with Tennessee): Iowa to the north, Illinois, Kentucky and Tennessee to the east, Arkansas t ...
that is legal under
federal law Federal law is the body of law created by the federal government of a country. A federal government is formed when a group of political units, such as states or provinces join in a federation, delegating their individual sovereignty and many po ...
, including
somatic cell nuclear transfer In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. The technique consists of taking an enucleated oocyte (egg cell) and implanting a ...
to produce human embryos for stem cell production. It prohibits cloning or attempting to clone a human being, which is defined to mean "to implant in a uterus or attempt to implant in a uterus anything other than the product of fertilisation of an
egg An egg is an organic vessel grown by an animal to carry a possibly fertilized egg cell (a zygote) and to incubate from it an embryo within the egg until the embryo has become an animal fetus that can survive on its own, at which point the a ...
of a human female by a sperm of a human male for the purpose of initiating a pregnancy that could result in the creation of a human
fetus A fetus or foetus (; plural fetuses, feti, foetuses, or foeti) is the unborn offspring that develops from an animal embryo. Following embryonic development the fetal stage of development takes place. In human prenatal development, fetal dev ...
, or the birth of a human being". Commercials supporting and opposing the amendment aired during the
2006 World Series The 2006 World Series was the championship series of Major League Baseball's (MLB) 2006 season. The 102nd edition of the World Series, it was a best-of-seven playoff between the American League (AL) champion Detroit Tigers and the National Lea ...
, in which the
St. Louis Cardinals The St. Louis Cardinals are an American professional baseball team based in St. Louis. The Cardinals compete in Major League Baseball (MLB) as a member club of the National League (NL) Central division. Since the 2006 season, the Cardinals ha ...
participated. The issue became especially intertwined with the 2006 U.S. Senate election in Missouri, with the
Republican Republican can refer to: Political ideology * An advocate of a republic, a type of government that is not a monarchy or dictatorship, and is usually associated with the rule of law. ** Republicanism, the ideology in support of republics or agains ...
and Democratic candidates on opposite sides of the issue. Missouri Constitutional Amendment 2 appeared on the ballot for the November 2006 general election and passed with 51% of the vote.


Support

The organization that led the movement to get the initiative on the ballot and later supported its adoption was called the Missouri Coalition for Lifesaving Cures. The measure was proposed to stop repeated attempts by the Missouri Legislature to ban certain types of stem cell research, namely SCNT.
Claire McCaskill Claire Conner McCaskill (; born July 24, 1953) is an American politician who served as a United States Senator from Missouri from 2007 to 2019 and as State Auditor of Missouri from 1999 to 2007. McCaskill is a native of Rolla, Missouri. She g ...
, the Democratic nominee for U.S. Senate, supported the measure. During the 2006 World Series, which was partially held in St. Louis, a television ad featuring actor
Michael J. Fox Michael Andrew Fox (born June 9, 1961), known professionally as Michael J. Fox, is a Canadian-American retired actor. Beginning his career in the 1970s, he rose to prominence portraying Alex P. Keaton on the NBC sitcom ''Family Ties'' (1 ...
aired. The ad was paid for by McCaskill's campaign, and the primary reason Fox gave for his support for McCaskill was her stance in favor of stem cell research. The advertisement was controversial because Fox was visibly suffering tremors, which were side effects of the medications used to treat Parkinson's Syndrome.
Rush Limbaugh Rush Hudson Limbaugh III ( ; January 12, 1951 – February 17, 2021) was an American conservative political commentator who was the host of '' The Rush Limbaugh Show'', which first aired in 1984 and was nationally syndicated on AM and FM r ...
, a conservative radio host, criticized Fox for allowing himself to have been used by special interests supporting the measure. Limbaugh criticized the uncontrollable movements that Fox made in the commercial, and claimed that it was Fox had either deliberately stopped taking his medication or was feigning his tremors.


Opposition

The coalition that initially led the opposition to the amendment was called Missourians Against Human Cloning. Later in the effort, when the coalition was unable to raise the money for the "Vote No" ads, Life Communications Fund took the lead in doing so. They created a series of "Vote No" ads for television, radio and print. Earlier in the campaign, the Vitae Foundation ran a series of educational ads, a "prophetic voice campaign," on the differences between adult and embryonic stem cell research, which was a major gain for those opposed to the Amendment, because, according to them, the "cures" were only occurring as a result of adult stem cell treatments, not via embryonic stem cells. Drawing awareness to the differences between adult and embryonic stem cell research was critical to their strategy. That was the goal of the first ad created in the series. Each ad then slowly moved the target audience (Catholics, Protestants and Evangelicals) to oppose the amendment. The final ad attempted to link embryonic stem cell research to human cloning. A majority of Missourians were opposed to human cloning, especially their target audience. The prophetic voice campaign ran for about 6 months. The "Vote No" ads ran for roughly 3 months.
Jim Talent James Matthes Talent (born October 18, 1956) is an American politician who was a U.S. Senator from Missouri from 2002 to 2007. He is a Republican and resided in the St. Louis area while serving in elected office. After serving for eight years ...
, the incumbent Republican U.S. Senator facing re-election, was one of several candidates opposed to the amendment. In rebuttal to the Michael J. Fox advertisement (which never directly mentioned Amendment 2), a Life Communications television ad with several celebrities appeared in opposition to the measure. At least three of the celebrities opposed the measure for religious reasons:
Kurt Warner Kurtis Eugene Warner (born June 22, 1971) is an American former football quarterback who played in the National Football League (NFL) for 12 seasons, primarily with the St. Louis Rams and Arizona Cardinals. His career, which saw him ascend f ...
, former
St. Louis Rams The St. Louis Rams were a professional American football team of the National Football League (NFL). They played in St. Louis from 1995 to the 2015 season, before moving back to Los Angeles, where the team had played from 1946 to 1994. The arr ...
quarterback; Kansas City Royals baseball player
Mike Sweeney Michael John Sweeney (born July 22, 1973) is a former Major League Baseball designated hitter and first baseman. Sweeney played his first 13 seasons in the majors with the Kansas City Royals, first as a catcher, then at first base and designated ...
, and
James Caviezel James Patrick Caviezel Jr. (; born September 26, 1968) is an American film and television actor who played Jesus Christ in ''The Passion of the Christ'' (2004) and starred as John Reese on the CBS series ''Person of Interest'' (2011–2016). He ...
, who played
Jesus Jesus, likely from he, יֵשׁוּעַ, translit=Yēšūaʿ, label= Hebrew/ Aramaic ( AD 30 or 33), also referred to as Jesus Christ or Jesus of Nazareth (among other names and titles), was a first-century Jewish preacher and religiou ...
in ''
The Passion of the Christ ''The Passion of the Christ'' is a 2004 American epic biblical drama film produced, directed and co-written by Mel Gibson and starring Jim Caviezel as Jesus of Nazareth, Maia Morgenstern as Mary, mother of Jesus, and Monica Bellucci as Mary ...
''.
Patricia Heaton Patricia Helen Heaton (born March 4, 1958) is an American actress and comedian. She is best known for her work on sitcoms, having played Debra Barone on ''Everybody Loves Raymond'' (1996–2005) as well as Frances "Frankie" Heck on '' The Middl ...
, from ''
Everybody Loves Raymond ''Everybody Loves Raymond'' is an American sitcom television series created by Philip Rosenthal that aired on CBS from September 13, 1996, to May 16, 2005, with a total of 210 episodes spanning nine seasons. It was produced by Where's Lunch an ...
'', opposed the amendment on the grounds that low-income women would be exploited for their eggs.
Jeff Suppan Jeffrey Scot Suppan (; born January 2, 1975), is an American former professional baseball pitcher and current professional baseball coach who played 17 seasons in Major League Baseball (MLB). He played for the Boston Red Sox, Arizona Diamondbacks, ...
, a pitcher for the
St. Louis Cardinals The St. Louis Cardinals are an American professional baseball team based in St. Louis. The Cardinals compete in Major League Baseball (MLB) as a member club of the National League (NL) Central division. Since the 2006 season, the Cardinals ha ...
, also appeared in opposition to the amendment.


Polling

As election day drew near, public support seemed to be shifting away from Amendment 2. Polls had shown support as high as 68% in favor of the Amendment in December 2005. By October 29, 2006, support had fallen to 51%, with 35% opposed.


Results and aftermath

On November 7, 2006, Amendment 2 passed by a margin of 2.4% (or 50,800 votes). The final tally of votes ended in 51.2% for yes and 48.8% for no. The measure failed in 97 of the 114 counties in the state, but picked up enough votes in St. Louis, Kansas City, and Columbia (and their surrounding counties) to pass statewide. Democrat Claire McCaskill (an amendment supporter) unseated Republican incumbent U.S. Senator Jim Talent (an amendment opponent) the same night that the amendment passed. The very expensive campaigns for and against the amendment broke every record on political spending on statewide races in Missouri. Following the passage of the amendment, the
Stowers Institute for Medical Research The Stowers Institute for Medical Research is a biomedical research organization that conducts basic research on genes and proteins that control fundamental processes in living cells to analyze diseases and find keys to their causes, treatment, ...
canceled plans for a major expansion in Kansas City. Because of the very close vote, the Institute asserted that the political climate in Missouri was too hostile for investment in stem cell research.{{cite web, url=https://articles.latimes.com/2007/aug/01/nation/na-stemcell1, title=Stem cell dissent roils states, first=Stephanie, last=Simon, date=1 August 2007, via=LA Times


References


External links


Full-text of Amendment 2Michael J. Fox ad for Claire McCaskill and stem cellsCelebrity Opposition Ad
Stem cell research 2006 Missouri elections 2006 ballot measures Missouri ballot measures Constitution of Missouri