Misonidazole is a
radiosensitizer
A radiosensitizer is an agent that makes tumor cells more sensitive to radiation therapy. It is sometimes also known as a radiation sensitizer or radio-enhancer.
Mechanism of action
Conventional chemotherapeutics are currently being used in c ...
that was investigated in
clinical trial
Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel v ...
s. It was used in these trials for
radiation therapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Rad ...
to cause normally resistant
hypoxic tumor cells to become sensitive to the treatment.
See also
*
Etanidazole
References
Secondary alcohols
Ethers
Nitroimidazoles
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