MINDO, or Modified Intermediate Neglect of Differential Overlap is a
semi-empirical
Empirical evidence for a proposition is evidence, i.e. what supports or counters this proposition, that is constituted by or accessible to sense experience or experimental procedure. Empirical evidence is of central importance to the sciences and ...
method for the
quantum
In physics, a quantum (plural quanta) is the minimum amount of any physical entity (physical property) involved in an interaction. The fundamental notion that a physical property can be "quantized" is referred to as "the hypothesis of quantizati ...
calculation of molecular electronic structure in
computational chemistry
Computational chemistry is a branch of chemistry that uses computer simulation to assist in solving chemical problems. It uses methods of theoretical chemistry, incorporated into computer programs, to calculate the structures and properties of m ...
. It is based on the Intermediate Neglect of Differential Overlap (
INDO) method of
John Pople. It was developed by the group of
Michael Dewar and was the original method in the
MOPAC program. The method should actually be referred to as MINDO/3. It was later replaced by the
MNDO method, which in turn was replaced by the
PM3 and
AM1 methods.
References
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Semiempirical quantum chemistry methods
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