Methylenediurea deaminase (, ''methylenediurease'') is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''methylenediurea aminohydrolase'' found in ''
Brucella anthropi'', a bacterium.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:
:
methylenediurea + 2 H
2O
N-(hydroxymethyl)urea + 2 NH
3 + CO
2 (overall reaction)
: (1a) methylenediurea + H
2O
N-(carboxyaminomethyl)urea + NH
3
: (1b) N-(carboxyaminomethyl)urea
N-(aminomethyl)urea + CO
2 (spontaneous)
: (1c) N-(aminomethyl)urea + H
2O
N-(hydroxymethyl)urea + NH
3 (spontaneous)
Methylenediurea is
hydrolysed
Hydrolysis (; ) is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution, elimination, and solvation reactions in which water is the nucleophile.
Biological hydrolysis ...
and
decarboxylated to give an aminated methylurea.
References
External links
*
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