Methyl Caffeate
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Methyl caffeate is an ester of
caffeic acid Caffeic acid is an organic compound that is classified as a hydroxycinnamic acid. This yellow solid consists of both phenolic and acrylic functional groups. It is found in all plants because it is an intermediate in the biosynthesis of lignin, one ...
, a naturally occurring phenolic compound. It is an
α-glucosidase Glycoside hydrolases (also called glycosidases or glycosyl hydrolases) catalyze the hydrolysis of glycosidic bonds in complex sugars. They are extremely common enzymes with roles in nature including degradation of biomass such as cellulose (cel ...
inhibitor. Its physical form is a powder.


Natural occurrences

Methyl caffeate can be found in the fruit of ''
Solanum torvum ''Solanum torvum'', the turkey berry, devil's fig, pea eggplant, platebrush or susumber, is a bushy, erect and spiny perennial plant used horticulturally as a rootstock for eggplant. Grafted plants are very vigorous and tolerate diseases affe ...
''.


Health effect

Methyl caffeate shows an
antidiabetic Drugs used in diabetes treat diabetes mellitus by altering the glucose level in the blood. With the exceptions of insulin, most GLP receptor agonists (liraglutide, exenatide, and others), and pramlintide, all are administered orally and are thus ...
effect in
streptozotocin Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring alkylating antineoplastic agent that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain canc ...
-induced diabetic rats.


References

O-methylated hydroxycinnamic acids Hydroxycinnamic acid esters Vinylogous carboxylic acids Catechols {{aromatic-stub