Metabolite Pool
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Metabolite pool is a collective term for all of the substances involved in the
metabolic Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...
process in a
biological system A biological system is a complex network which connects several biologically relevant entities. Biological organization spans several scales and are determined based different structures depending on what the system is. Examples of biological syst ...
. Metabolic pools are within cells (or
organelles In cell biology, an organelle is a specialized subunit, usually within a cell, that has a specific function. The name ''organelle'' comes from the idea that these structures are parts of cells, as organs are to the body, hence ''organelle,'' the ...
such as
chloroplasts A chloroplast () is a type of membrane-bound organelle known as a plastid that conducts photosynthesis mostly in plant cell, plant and algae, algal cells. The photosynthetic pigment chlorophyll captures the energy from sunlight, converts it, ...
) and refer to the reservoir of
molecules A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...
upon which
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
s can operate. The size of the reservoir is referred to as its "metabolic pool." The metabolic pool concept is important to
cellular biology Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and ...
. In certain ways, a
metabolic pathway In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites, which are modified by a sequence of chemical reac ...
is similar to a factory assembly line. Products are assembled from parts by workers who each perform a specific step in the manufacturing process. Enzymes of a cell are like workers on an assembly line; each is only responsible for a particular step in the assembly process. A lag period also occurs when a new factory is constructed, a time period before finished products begin to roll off the assembly line at a steady rate. This lag period partially results from the time needed to fill supply bins with the necessary parts. As you might imagine, when parts are not readily available, production slows or stops. Metabolite pools are somewhat analogous to the parts bins of a factory. The Calvin-Benson cycle will only operate at full speed when the cellular 'bins' are full of the molecular building blocks that lie between PGA and
RUBP Ribulose 1,5-bisphosphate (RuBP) is an organic substance that is involved in photosynthesis, notably as the principal acceptor in plants. It is a colourless anion, a double phosphate ester of the ketopentose ( ketone-containing sugar with five c ...
.


References

Systems biology {{Biology-stub