Mesuximide
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Mesuximide (or methsuximide, methosuximide) is a
succinimide Succinimide is an organic compound with the formula (CH2)2(CO)2NH. This white solid is used in a variety of organic syntheses, as well as in some industrial silver plating processes. The compound is classified as a cyclic imide. It may be prepared ...
anticonvulsant medication. It is sold as a
racemate In chemistry, a racemic mixture, or racemate (), is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt. Racemic mixtures are rare in nature, but many compounds are produced industrially as racemates. ...
by
Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...
under the tradenames Petinutin (Switzerland) and Celontin (United States). The therapeutic efficacy of methosuximide is largely due to its pharmacologically active metabolite, ''N''-desmethylmethosuximide, which has a longer half-life and attains much higher plasma levels than its parent.


Medical use

is indicated for the control of absence seizures that are refractory to other drugs.


References

Anticonvulsants Succinimides {{anticonvulsant-stub