(+)-Menthofuran synthase (, ''menthofuran synthase'', ''(+)-pulegone 9-hydroxylase'', ''(+)-MFS'', ''cytochrome P450 menthofuran synthase'') is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

with

systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...

''(+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating)''. This enzyme catalyses the following

chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...

: (+)-

pulegone Pulegone is a naturally occurring organic compound obtained from the essential oils of a variety of plants such as ''Nepeta cataria'' (catnip), ''Mentha piperita'', and pennyroyal. It is classified as a monoterpene. Pulegone is a clear colorles ...

+ NADPH + H⁺ + O₂

\rightleftharpoons

(+)-

menthofuran Menthofuran is an organic compound found in a variety of essential oils including that of pennyroyal (''Mentha pulegium''). It is highly toxic and believed to be the primary toxin in pennyroyal responsible for its potentially fatal effects. Af ...

+ NADP+ + H₂O Menthofuran synthase is a

heme Heme, or haem (pronounced / hi:m/ ), is a precursor to hemoglobin, which is necessary to bind oxygen in the bloodstream. Heme is biosynthesized in both the bone marrow and the liver. In biochemical terms, heme is a coordination complex "consisti ...

thiol In organic chemistry, a thiol (; ), or thiol derivative, is any organosulfur compound of the form , where R represents an alkyl or other organic substituent. The functional group itself is referred to as either a thiol group or a sulfhydryl gro ...

ate protein (P-450).

References

External links

* {{Portal bar, Biology, border=no EC 1.14.13