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Peppermint (''Mentha'' × ''piperita'') is a
hybrid Hybrid may refer to: Science * Hybrid (biology), an offspring resulting from cross-breeding ** Hybrid grape, grape varieties produced by cross-breeding two ''Vitis'' species ** Hybridity, the property of a hybrid plant which is a union of two dif ...
species of
mint MiNT is Now TOS (MiNT) is a free software alternative operating system kernel for the Atari ST system and its successors. It is a multi-tasking alternative to TOS and MagiC. Together with the free system components fVDI device drivers, XaAES g ...
, a cross between watermint and
spearmint Spearmint, also known as garden mint, common mint, lamb mint and mackerel mint, is a species of mint, ''Mentha spicata'' (, native to Europe and southern temperate Asia, extending from Ireland in the west to southern China in the east. It is nat ...
. Indigenous to Europe and the Middle East, the plant is now widely spread and cultivated in many regions of the world.Euro+Med Plantbase Project
''Mentha'' × ''piperita''
/ref> It is occasionally found in the wild with its parent species.Flora of NW Europe
''Mentha'' × ''piperita''
Although the genus ''Mentha'' comprises more than 25 species, the one in most common use is peppermint. While Western peppermint is derived from ''Mentha × piperita'', Chinese peppermint, or ''bohe'', is derived from the fresh leaves of ''M. haplocalyx''. ''M. × piperita'' and ''M. haplocalyx'' are both recognized as plant sources of
menthol Menthol is an organic compound, more specifically a monoterpenoid, made synthetically or obtained from the oils of corn mint, peppermint, or other mints. It is a waxy, clear or white crystalline substance, which is solid at room temperature and ...
and
menthone Menthone is a monoterpene with a minty flavor that occurs naturally in a number of essential oils. ''l''-Menthone (or (2''S'',5''R'')-''trans''-2-isopropyl-5-methylcyclohexanone), shown at right, is the most abundant in nature of the four possible ...
, and are among the oldest herbs used for both culinary and medicinal products.


Botany

Peppermint was first described in 1753 by
Carl Linnaeus Carl Linnaeus (; 23 May 1707 – 10 January 1778), also known after his ennoblement in 1761 as Carl von Linné Blunt (2004), p. 171. (), was a Swedish botanist, zoologist, taxonomist, and physician who formalised binomial nomenclature, the ...
from specimens that had been collected in England; he treated it as a
species In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate s ...
,Linnaeus, C. (1753). ''
Species Plantarum ' (Latin for "The Species of Plants") is a book by Carl Linnaeus, originally published in 1753, which lists every species of plant known at the time, classified into genera. It is the first work to consistently apply binomial names and was the ...
'' 2: 576–577.
but it is now universally agreed to be a hybrid.Harley, R. M. (1975). ''Mentha'' L. In:
Stace, C. A. Clive Anthony Stace (born 1938) is a British botanist and botanical author. He studied at King's College London, graduated from University of London in 1959 and then studied at the Natural History Museum, London. He was awarded a PhD in 1963. ...
, ed. ''Hybridization and the flora of the British Isles'' page 387.
It is a
herbaceous Herbaceous plants are vascular plants that have no persistent woody stems above ground. This broad category of plants includes many perennials, and nearly all annuals and biennials. Definitions of "herb" and "herbaceous" The fourth edition of t ...
, rhizomatous,
perennial plant A perennial plant or simply perennial is a plant that lives more than two years. The term ('' per-'' + '' -ennial'', "through the years") is often used to differentiate a plant from shorter-lived annuals and biennials. The term is also wide ...
that grows to be tall, with smooth stems, square in cross section. The
rhizome In botany and dendrology, a rhizome (; , ) is a modified subterranean plant stem that sends out roots and shoots from its nodes. Rhizomes are also called creeping rootstalks or just rootstalks. Rhizomes develop from axillary buds and grow hori ...
s are wide-spreading and fleshy, and bear fibrous
root In vascular plants, the roots are the organs of a plant that are modified to provide anchorage for the plant and take in water and nutrients into the plant body, which allows plants to grow taller and faster. They are most often below the sur ...
s. The
leaves A leaf (plural, : leaves) is any of the principal appendages of a vascular plant plant stem, stem, usually borne laterally aboveground and specialized for photosynthesis. Leaves are collectively called foliage, as in "autumn foliage", wh ...
can be long and broad. They are dark green with reddish veins, with an acute apex and coarsely toothed margins. The leaves and stems are usually slightly fuzzy. The
flower A flower, sometimes known as a bloom or blossom, is the reproductive structure found in flowering plants (plants of the division Angiospermae). The biological function of a flower is to facilitate reproduction, usually by providing a mechani ...
s are purple, long, with a four-lobed corolla about diameter; they are produced in whorls (verticillasters) around the stem, forming thick, blunt spikes. Flowering season lasts from mid- to late summer. The
chromosome A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are ...
number is variable, with 2n counts of 66, 72, 84, and 120 recorded.Huxley, A., ed. (1992). ''New RHS Dictionary of Gardening''. Macmillan. .Blamey, M. & Grey-Wilson, C. (1989). ''Flora of Britain and Northern Europe''. Peppermint is a fast-growing plant; once it sprouts, it spreads very quickly.


Ecology

Peppermint typically occurs in moist habitats, including stream sides and drainage ditches. Being a hybrid, it is usually
sterile Sterile or sterility may refer to: *Asepsis, a state of being free from biological contaminants * Sterile (archaeology), a sediment deposit which contains no evidence of human activity *Sterilization (microbiology), any process that eliminates or ...
, producing no
seed A seed is an embryonic plant enclosed in a protective outer covering, along with a food reserve. The formation of the seed is a part of the process of reproduction in seed plants, the spermatophytes, including the gymnosperm and angiospe ...
s and reproducing only
vegetatively Vegetative reproduction (also known as vegetative propagation, vegetative multiplication or cloning) is any form of asexual reproduction occurring in plants in which a new plant grows from a fragment or cutting of the parent plant or spec ...
, spreading by its runners. Outside of its native range, areas where peppermint was formerly grown for oil often have an abundance of feral plants, and it is considered
invasive Invasive may refer to: *Invasive (medical) procedure *Invasive species *Invasive observation, especially in reference to surveillance *Invasively progressive spread of disease from one organ in the body to another, especially in reference to cancer ...
in Australia, the
Galápagos Islands The Galápagos Islands (Spanish: , , ) are an archipelago of volcanic islands. They are distributed on each side of the equator in the Pacific Ocean, surrounding the centre of the Western Hemisphere, and are part of the Republic of Ecuador ...
, New Zealand,Pacific Island Ecosystems at Risk
''Mentha'' x ''piperita''
and the United States in the
Great Lakes The Great Lakes, also called the Great Lakes of North America, are a series of large interconnected freshwater lakes in the mid-east region of North America that connect to the Atlantic Ocean via the Saint Lawrence River. There are five lakes ...
region, noted since 1843.


Cultivation

Peppermint generally grows best in moist, shaded locations, and expands by underground rhizomes. Young shoots are taken from old stocks and dibbled into the ground about 0.5 m (1.5 ft) apart. They grow quickly and cover the ground with runners if it is permanently moist. For the home gardener, it is often grown in containers to restrict rapid spreading. It grows best with a good supply of water, without being water-logged, and planted in areas with partial sun to shade. The leaves and flowering tops are used; they are collected as soon as the flowers begin to open and can be dried. The wild form of the plant is less suitable for this purpose, with cultivated plants having been selected for more and better oil content. They may be allowed to lie and wilt a little before distillation, or they may be taken directly to the still.


Cultivars

Several
cultivar A cultivar is a type of cultivated plant that people have selected for desired traits and when propagated retain those traits. Methods used to propagate cultivars include: division, root and stem cuttings, offsets, grafting, tissue culture, ...
s have been selected for garden use: * ''Mentha'' × ''piperita'' 'Candymint' has reddish stems. * ''Mentha'' × ''piperita'' 'Chocolate Mint'. Its flowers open from the bottom up; its flavour is reminiscent of the flavour in
Andes Chocolate Mints Andes Chocolate Mints are small rectangular candies. The crème de menthe variety consists of one mint-green layer sandwiched in between two cocoa based chocolate flavored layers. The candies are usually wrapped in green foil and imprinted with ...
, a popular confection. * ''Mentha'' × ''piperita'' 'Citrata' includes a number of varieties including 'eau de Cologne' mint, grapefruit mint, lemon mint, and orange mint. Its leaves are aromatic and hairless. * ''Mentha'' × ''piperita'' 'Crispa' has wrinkled leaves. * ''Mentha'' × ''piperita'' 'Lavender Mint' * ''Mentha'' × ''piperita'' 'Lime Mint' has lime-scented foliage. * ''Mentha'' × ''piperita'' 'Variegata' has mottled green and pale yellow leaves. Commercial cultivars may include: * Dulgo pole * Zefir * Bulgarian population #2 * Clone 11-6-22 * Clone 80-121-33 * Mitcham Digne 38 * Mitcham Ribecourt 19 * ' Todd's Mitcham', a
verticillium wilt Verticillium wilt is a wilt disease affecting over 350 species of eudicot plants. It is caused by six species of ''Verticillium'' fungi: ''V. dahliae'', ''V. albo-atrum'', ''V. longisporum'', ''V. nubilum'', ''V. theobromae'' and ''V. tricorpu ...
-resistant cultivar produced from a breeding and test program of
atomic gardening Atomic gardening is a form of mutation breeding where plants are exposed to radiation. Some of the mutations produced thereby have turned out to be useful. Typically this is gamma radiation in which case it is a produced by cobalt-60. The pra ...
at
Brookhaven National Laboratory Brookhaven National Laboratory (BNL) is a United States Department of Energy national laboratory located in Upton, Long Island, and was formally established in 1947 at the site of Camp Upton, a former U.S. Army base and Japanese internment c ...
from the mid-1950s * '
Refined Murray Peppermint (''Mentha'' × ''piperita'') is a hybrid species of mint, a cross between watermint and spearmint. Indigenous to Europe and the Middle East, the plant is now widely spread and cultivated in many regions of the world.Euro+Med Plantbas ...
', also verticillium-resistant * ' Roberts Mitcham', also verticillium-resistant and also the product of
mutation breeding Mutation breeding, sometimes referred to as "variation breeding", is the process of exposing seeds to chemicals, radiation, or enzymes in order to generate mutants with desirable traits to be bred with other cultivars. Plants created using mutagene ...


Diseases

Verticillium wilt Verticillium wilt is a wilt disease affecting over 350 species of eudicot plants. It is caused by six species of ''Verticillium'' fungi: ''V. dahliae'', ''V. albo-atrum'', ''V. longisporum'', ''V. nubilum'', ''V. theobromae'' and ''V. tricorpu ...
is a major constraint in peppermint cultivation. 'Todd's Mitcham', 'Refined Murray', 'Roberts Mitcham' (see above), and a few other cultivars have some degree of
resistance Resistance may refer to: Arts, entertainment, and media Comics * Either of two similarly named but otherwise unrelated comic book series, both published by Wildstorm: ** ''Resistance'' (comics), based on the video game of the same title ** ''T ...
.


Production

In 2020, world production of peppermint was 48,437
tonne The tonne ( or ; symbol: t) is a unit of mass equal to 1000  kilograms. It is a non-SI unit accepted for use with SI. It is also referred to as a metric ton to distinguish it from the non-metric units of the short ton ( United State ...
s, led by
Morocco Morocco (),, ) officially the Kingdom of Morocco, is the westernmost country in the Maghreb region of North Africa. It overlooks the Mediterranean Sea to the north and the Atlantic Ocean to the west, and has land borders with Algeria to ...
with 83% of the world total and
Argentina Argentina (), officially the Argentine Republic ( es, link=no, República Argentina), is a country in the southern half of South America. Argentina covers an area of , making it the second-largest country in South America after Brazil, th ...
with 14% (table). In the United States,
Oregon Oregon () is a U.S. state, state in the Pacific Northwest region of the Western United States. The Columbia River delineates much of Oregon's northern boundary with Washington (state), Washington, while the Snake River delineates much of it ...
and
Washington Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered on ...
produce most of the country's peppermint, the leaves of which are processed for the
essential oil An essential oil is a concentrated hydrophobic liquid containing volatile (easily evaporated at normal temperatures) chemical compounds from plants. Essential oils are also known as volatile oils, ethereal oils, aetheroleum, or simply as the o ...
to produce
flavoring A flavoring (or flavouring), also known as flavor (or flavour) or flavorant, is a food additive used to improve the taste or smell of food. It changes the perceptual impression of food as determined primarily by the chemoreceptors of the gusta ...
s mainly for
chewing gum Chewing gum is a soft, cohesive substance designed to be chewed without being swallowed. Modern chewing gum is composed of gum base, sweeteners, softeners/plasticizers, flavors, colors, and, typically, a hard or powdered polyol coating. Its te ...
and
toothpaste Toothpaste is a paste or gel dentifrice used with a toothbrush to clean and maintain the aesthetics and health of teeth. Toothpaste is used to promote oral hygiene: it is an abrasive that aids in removing dental plaque and food from the teeth, a ...
.


Chemical constituents

Peppermint has a high menthol content. The essential oil also contains menthone and carboxyl esters, particularly
menthyl acetate Menthyl acetate is a natural monoterpene which contributes to the smell and flavor of peppermint. It is the acetate ester of menthol. Menthyl acetate constitutes 3–5% of the volatile oil of ''mentha piperita'', contributing to its smell and f ...
. Dried peppermint typically has 0.3–0.4% of volatile oil containing menthol (7–48%), menthone (20–46%), menthyl acetate (3–10%),
menthofuran Menthofuran is an organic compound found in a variety of essential oils including that of pennyroyal (''Mentha pulegium''). It is highly toxic and believed to be the primary toxin in pennyroyal responsible for its potentially fatal effects. Af ...
(1–17%), and 1,8-
cineol Eucalyptol is a monoterpenoid. A colorless liquid, it is a bicyclic ether. Eucalyptol has a fresh mint-like smell and a spicy, cooling taste. It is insoluble in water, but miscible with organic solvents. Eucalyptol makes up ~70% - 90% of eucal ...
(3–6%). Peppermint oil also contains small amounts of many additional compounds, including
limonene Limonene is a colorless liquid aliphatic hydrocarbon classified as a cyclic monoterpene, and is the major component in the oil of citrus fruit peels. The -isomer, occurring more commonly in nature as the fragrance of oranges, is a flavoring ag ...
,
pulegone Pulegone is a naturally occurring organic compound obtained from the essential oils of a variety of plants such as ''Nepeta cataria'' (catnip), ''Mentha piperita'', and pennyroyal. It is classified as a monoterpene. Pulegone is a clear colorles ...
,
caryophyllene Caryophyllene (), more formally (−)-β-caryophyllene, (BCP), is a natural bicyclic sesquiterpene that is a constituent of many essential oils, especially clove oil, the oil from the stems and flowers of '' Syzygium aromaticum'' (cloves), the ess ...
, and
pinene Pinene is a collection of unsaturated bicyclic monoterpenes. Two geometric isomers of pinene are found in nature, α-pinene and β-pinene. Both are chiral. As the name suggests, pinenes are found in pines. Specifically, pinene is the major compo ...
. Peppermint contains
terpenoid The terpenoids, also known as isoprenoids, are a class of naturally occurring organic chemicals derived from the 5-carbon compound isoprene and its derivatives called terpenes, diterpenes, etc. While sometimes used interchangeably with "terpenes" ...
s and
flavonoid Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids ...
s such as
eriocitrin Eriocitrin (eriodictyol glycoside) is a flavanone-7-''O''-glycoside between the flavanone eriodictyol and the disaccharide rutinose. It is commonly found in lemons and other citrus fruits. It is colloquially called lemon flavonoid or a citrus fla ...
,
hesperidin Hesperidin is a flavanone glycoside found in citrus fruits. Its aglycone form is called hesperetin. Its name is derived from the word "hesperidium", for fruit produced by citrus trees. Hesperidin was first isolated in 1828 by French chemist M. ...
, and
kaempferol Kaempferol (3,4′,5,7-tetrahydroxyflavone) is a natural flavonol, a type of flavonoid, found in a variety of plants and plant-derived foods including kale, beans, tea, spinach, and broccoli. Kaempferol is a yellow crystalline solid with a meltin ...
7-O-rutinoside.


Oil

Peppermint oil has a high concentration of natural pesticides, mainly pulegone (found mainly in ''M. arvensis'' var. ''piperascens'' (cornmint, field mint, or Japanese mint), and to a lesser extent (6,530 ppm) in ''Mentha'' × ''piperita'' subsp. ''notho'') and menthone. It is known to repel some pest insects, including
mosquito Mosquitoes (or mosquitos) are members of a group of almost 3,600 species of small flies within the family Culicidae (from the Latin ''culex'' meaning " gnat"). The word "mosquito" (formed by ''mosca'' and diminutive ''-ito'') is Spanish for "li ...
s, and has uses in organic gardening. It is also widely used to repel rodents. Peppermint oil can also be used as an effective remedy for nausea and digestive issues. The chemical composition of the essential oil from peppermint (''Mentha'' × ''piperita'' L.) was analyzed by GC/FID and GC-MS. The main constituents were
menthol Menthol is an organic compound, more specifically a monoterpenoid, made synthetically or obtained from the oils of corn mint, peppermint, or other mints. It is a waxy, clear or white crystalline substance, which is solid at room temperature and ...
(40.7%) and
menthone Menthone is a monoterpene with a minty flavor that occurs naturally in a number of essential oils. ''l''-Menthone (or (2''S'',5''R'')-''trans''-2-isopropyl-5-methylcyclohexanone), shown at right, is the most abundant in nature of the four possible ...
(23.4%). Further components were (±)-
menthyl acetate Menthyl acetate is a natural monoterpene which contributes to the smell and flavor of peppermint. It is the acetate ester of menthol. Menthyl acetate constitutes 3–5% of the volatile oil of ''mentha piperita'', contributing to its smell and f ...
, 1,8-
cineole Eucalyptol is a monoterpenoid. A colorless liquid, it is a bicyclic ether. Eucalyptol has a fresh mint-like smell and a spicy, cooling taste. It is insoluble in water, but miscible with organic solvents. Eucalyptol makes up ~70% - 90% of eucaly ...
,
limonene Limonene is a colorless liquid aliphatic hydrocarbon classified as a cyclic monoterpene, and is the major component in the oil of citrus fruit peels. The -isomer, occurring more commonly in nature as the fragrance of oranges, is a flavoring ag ...
, beta-pinene, and
beta-caryophyllene Caryophyllene (), more formally (−)-β-caryophyllene, (BCP), is a natural bicyclic sesquiterpene that is a constituent of many essential oils, especially clove oil, the oil from the stems and flowers of '' Syzygium aromaticum'' (cloves), the es ...
.


Research and health effects

Peppermint oil Peppermint extract is an herbal extract of peppermint (''Mentha × piperita'') made from the essential oils of peppermint leaves. Peppermint is a hybrid of water mint and spearmint and was indigenous to Europe and the Middle East before it became c ...
is under preliminary research for its potential as a short-term treatment for
irritable bowel syndrome Irritable bowel syndrome (IBS) is a "disorder of gut-brain interaction" characterized by a group of symptoms that commonly include abdominal pain and or abdominal bloating and changes in the consistency of bowel movements. These symptoms may ...
, and has supposed uses in
traditional medicine Traditional medicine (also known as indigenous medicine or folk medicine) comprises medical aspects of traditional knowledge that developed over generations within the folk beliefs of various societies, including indigenous peoples, before the ...
for minor ailments. Peppermint oil and leaves have a cooling effect when used
topical A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes ...
ly for
muscle pain Myalgia (also called muscle pain and muscle ache in layman's terms) is the medical term for muscle pain. Myalgia is a symptom of many diseases. The most common cause of acute myalgia is the overuse of a muscle or group of muscles; another likel ...
,
nerve pain Neuropathic pain is pain caused by damage or disease affecting the somatosensory system. Neuropathic pain may be associated with abnormal sensations called dysesthesia or pain from normally non-painful stimuli (allodynia). It may have continuous ...
, relief from
itch Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch. Itch has resisted many attempts to be classified as any one type of sensory experience. Itch has many similarities to pain, and while both are unpleasant ...
ing, or as a fragrance. High oral doses of peppermint oil (500 mg) can cause mucosal irritation and mimic
heartburn Heartburn, also known as pyrosis, cardialgia or acid indigestion, is a burning sensation in the central chest or upper central abdomen. Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus. It is the ma ...
. Peppermint roots
bioaccumulate Bioaccumulation is the gradual accumulation of substances, such as pesticides or other chemicals, in an organism. Bioaccumulation occurs when an organism absorbs a substance at a rate faster than that at which the substance is lost or eliminated ...
radium Radium is a chemical element with the symbol Ra and atomic number 88. It is the sixth element in group 2 of the periodic table, also known as the alkaline earth metals. Pure radium is silvery-white, but it readily reacts with nitrogen (rather t ...
, so the plant may be effective for
phytoremediation Phytoremediation technologies use living plants to clean up soil, air and water contaminated with hazardous contaminants. It is defined as "the use of green plants and the associated microorganisms, along with proper soil amendments and agronomi ...
of radioactively contaminated soil.


Culinary and other uses

Fresh or dried peppermint leaves are often used alone in
peppermint tea Maghrebi mint tea (Maghrebi Arabic: , ''atay''; ar, الشاي بالنعناع, aš-šhāy bin-na'nā'; ), also known as Moroccan mint tea and Algerian mint tea, is a North African green tea prepared with spearmint leaves and sugar. It is tr ...
or with other herbs in
herbal tea Herbal teas, also known as herbal infusions and less commonly called tisanes (UK and US , US also ), are beverages made from the infusion or decoction of herbs, spices, or other plant material in hot water. Oftentimes herb tea, or the plain term ...
s (tisanes, infusions). Peppermint is used for flavouring
ice cream Ice cream is a sweetened frozen food typically eaten as a snack or dessert. It may be made from milk or cream and is flavoured with a sweetener, either sugar or an alternative, and a spice, such as cocoa or vanilla, or with fruit such as str ...
,
candy Candy, also called sweets (British English) or lollies (Australian English Australian English (AusE, AusEng, AuE, AuEng, en-AU) is the set of varieties of the English language native to Australia. It is the country's common language an ...
,
fruit preserve Fruit preserves are preparations of fruits whose main preserving agent is sugar and sometimes acid, often stored in glass jars and used as a condiment or spread. There are many varieties of fruit preserves globally, distinguished by the method ...
s,
alcoholic beverage An alcoholic beverage (also called an alcoholic drink, adult beverage, or a drink) is a drink that contains ethanol, a type of alcohol that acts as a drug and is produced by fermentation of grains, fruits, or other sources of sugar. The c ...
s, chewing gum, toothpaste, and some shampoos, soaps, and skin care products. Menthol activates cold-sensitive
TRPM8 Transient receptor potential cation channel subfamily M (melastatin) member 8 (TRPM8), also known as the cold and menthol receptor 1 (CMR1), is a protein that in humans is encoded by the ''TRPM8'' gene. The TRPM8 channel is the primary molecular t ...
receptors in the skin and mucosal tissues, and is the primary source of the cooling sensation that follows the topical application of peppermint oil. File:Candy-Cane-Classic.jpg,
Candy canes A candy cane is a cane-shaped stick candy often associated with Christmastide, as well as Saint Nicholas Day. It is traditionally white with red stripes and flavored with peppermint, but they also come in a variety of other flavors and colors. ...
are one of the most common peppermint-flavored candies File:CSA-Chocolate-Mint.jpg, ''Mentha'' × ''piperita'' hybrid known as 'Chocolate Mint' File:Pfefferminze ies.jpg, Freeze-dried leaves
Peppermint oil is also used in construction and plumbing to test for the tightness of pipes and disclose leaks by its odor.


Safety

Medicinal uses of peppermint have not been approved as effective or safe by the US
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
. With caution that the concentration of the peppermint constituent pulegone should not exceed 1% (140 mg), peppermint preparations are considered safe by the
European Medicines Agency The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of medicinal products. Prior to 2004, it was known as the European Agency for the Evaluation of Medicinal Products or Euro ...
when used in topical formulations for adult subjects. Diluted peppermint essential oil is safe for oral intake when only a few drops are used. Although peppermint is commonly available as a
herbal supplement Herbal medicine (also herbalism) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. With worldwide research into pharmacology, some herbal medicines have been translated into modern remedies ...
, no established, consistent manufacturing standards exist for it, and some peppermint products may be contaminated with toxic metals or other substituted compounds.
Skin rash A rash is a change of the human skin which affects its color, appearance, or texture. A rash may be localized in one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, chapped, dry, cr ...
es, irritation, or
allergic reactions Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...
may result from applying peppermint oil to the skin, and its use on the face or chest of young children may cause side effects if the oil menthol is inhaled. A common side effect from oral intake of peppermint oil or capsules is
heartburn Heartburn, also known as pyrosis, cardialgia or acid indigestion, is a burning sensation in the central chest or upper central abdomen. Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus. It is the ma ...
. Oral use of peppermint products may have
adverse effect An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect. The term complica ...
s when used with iron supplements,
cyclosporine Ciclosporin, also spelled cyclosporine and cyclosporin, is a calcineurin inhibitor, used as an immunosuppressant medication. It is a natural product. It is taken orally or intravenously for rheumatoid arthritis, psoriasis, Crohn's disease ...
, medicines for heart conditions or high blood pressure, or medicines to decrease stomach acid.


Standardization

* ISO 676:1995—contains the information about the nomenclature of the variety and cultivars * ISO 5563:1984—a specification for its dried leaves of Mentha piperita Linnaeus * Peppermint oil—
ISO 856 ISO is the most common abbreviation for the International Organization for Standardization. ISO or Iso may also refer to: Business and finance * Iso (supermarket), a chain of Danish supermarkets incorporated into the SuperBest chain in 2007 * Iso ...
:2006


See also

*
Eucalyptus ''Eucalyptus'' () is a genus of over seven hundred species of flowering trees, shrubs or mallees in the myrtle family, Myrtaceae. Along with several other genera in the tribe Eucalypteae, including '' Corymbia'', they are commonly known as euca ...
*
Peppermint extract Peppermint extract is an herbal extract of peppermint (''Mentha × piperita'') made from the essential oils of peppermint leaves. Peppermint is a hybrid of water mint and spearmint and was indigenous to Europe and the Middle East before it became co ...


References

{{Authority control Antiemetics Flora of Europe Herbs Medicinal plants Mentha Plants described in 1753 Hybrid plants