Melinta Therapeutics, founded in 2000 as Rib-X Pharmaceuticals, is an American publicly traded
biopharmaceutical
A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. Different from totally synthesized pharmaceuticals, t ...
firm that focuses on the design and development of novel
broad-spectrum antibiotic
A broad-spectrum antibiotic is an antibiotic that acts on the two major bacterial groups, Gram-positive and Gram-negative, or any antibiotic that acts against a wide range of disease-causing bacteria. These medications are used when a bacterial inf ...
s for the treatment of antibiotic-resistant infections in hospital and community settings. The company is located in
New Haven, Connecticut
New Haven is a city in the U.S. state of Connecticut. It is located on New Haven Harbor on the northern shore of Long Island Sound in New Haven County, Connecticut and is part of the New York City metropolitan area. With a population of 134,02 ...
.
In mid-2011,
Sanofi
Sanofi S.A. is a French multinational pharmaceutical and healthcare company headquartered in Paris, France. Originally, the corporation was established in 1973 and merged with Synthélabo in 1999 to form Sanofi-Synthélabo. In 2004, Sanofi-Syn ...
entered into a global research collaboration and licensing option with the company to develop and commercialize novel antibiotics.
[ It was renamed Melinta Therapeutics in 2013.]fluoroquinolone
A quinolone antibiotic is a member of a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. They are used in human and veterinary medicine to treat bacterial infections, as wel ...
antibiotic acquired from Wakunaga Pharmaceutical in 2006,FDA
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
in 2017.
As of 2016, the company was also developing radezolid
Radezolid (International Nonproprietary Name, INN, codenamed RX-1741) is a novel oxazolidinone antibiotic being developed by Melinta Therapeutics, Inc. for the treatment of bacterial acne.
References
Further reading
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Oxazo ...
, a next-generation oxazolidinone
2-Oxazolidone is a heterocyclic organic compound containing both nitrogen and oxygen in a 5-membered ring.
Oxazolidinones
Evans auxiliaries
Oxazolidinones are a class of compounds containing 2-oxazolidone in the structure. In chemistry, they are ...
for bacterial acne.[
Melinta shredded off its discovery research team in late 2018.]Chapter 11
Chapter 11 of the United States Bankruptcy Code (Title 11 of the United States Code) permits reorganization under the bankruptcy laws of the United States. Such reorganization, known as Chapter 11 bankruptcy, is available to every business, wheth ...
bankruptcy protection.Deerfield Management
Deerfield Management ("Deerfield") is an American investment firm headquartered in New York City. It is focused on making public and private investments in the healthcare and biotechnology industries. Deerfield is considered to be one of the la ...
.
References
External links
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Pharmaceutical companies based in New Jersey
Pharmaceutical companies of the United States
Pharmaceutical companies established in 2000
Companies that filed for Chapter 11 bankruptcy in 2019
Morristown, New Jersey
Companies based in Morris County, New Jersey
2000 establishments in Connecticut