Medical gloves are disposable
gloves used during medical examinations and procedures to help prevent cross-contamination between caregivers and patients. Medical gloves are made of different polymers including
latex
Latex is an emulsion (stable dispersion) of polymer microparticles in water. Latexes are found in nature, but synthetic latexes are common as well.
In nature, latex is found as a milky fluid found in 10% of all flowering plants (angiosperms ...
,
nitrile rubber
Nitrile rubber, also known as nitrile butadiene rubber, NBR, Buna-N, and acrylonitrile butadiene rubber, is a synthetic rubber derived from acrylonitrile (ACN) and butadiene. Trade names include Perbunan, Nipol, Krynac and Europrene. This rubber is ...
,
polyvinyl chloride and
neoprene
Neoprene (also polychloroprene) is a family of synthetic rubbers that are produced by polymerization of chloroprene.Werner Obrecht, Jean-Pierre Lambert, Michael Happ, Christiane Oppenheimer-Stix, John Dunn and Ralf Krüger "Rubber, 4. Emulsion R ...
; they come unpowdered, or powdered with
corn starch
Corn starch, maize starch, or cornflour (British English) is the starch derived from corn (maize) grain. The starch is obtained from the endosperm of the kernel. Corn starch is a common food ingredient, often used to thicken sauces or sou ...
to lubricate the gloves, making them easier to put on the hands.
Corn starch replaced tissue-irritating
lycopodium powder
Lycopodium powder is a yellow-tan dust-like powder, consisting of the dry spores of clubmoss plants, or various fern relatives. When it is mixed with air, the spores are highly flammable and are used to create dust explosions as theatrical spec ...
and talc, but even corn starch can impede healing if it gets into tissues (as during surgery). As such, unpowdered gloves are used more often during surgery and other sensitive procedures. Special manufacturing processes are used to compensate for the lack of powder.
There are two main types of medical gloves: examination and surgical. Surgical gloves have more precise sizing with a better precision and sensitivity and are made to a higher standard. Examination gloves are available as either sterile or non-sterile, while surgical gloves are generally sterile.
Besides medicine, medical gloves are widely used in chemical and biochemical laboratories. Medical gloves offer some basic protection against corrosives and surface contamination. However, they are easily penetrated by solvents and various hazardous chemicals, and should not be used for dishwashing or otherwise when the task involves immersion of the gloved hand in the solvent.
Medical gloves are recommended to be worn for two main reasons:
# To reduce the risk of contamination of health-care workers hands with blood and other body fluids.
# To reduce the risk of germ dissemination to the environment and of transmission from the health-care worker to the patient and vice versa, as well as from one patient to another.
History
Caroline Hampton
Caroline Hampton Halsted (20 November 1861 – 27 November 1922) was a nurse who became the first to use medical gloves in the operating room.
Biography
Caroline Hampton was a member of a prominent southern family; her uncle, Wade Hampton III, was ...
became the chief nurse of the operating room when
Johns Hopkins Hospital
The Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of the Johns Hopkins School of Medicine, located in Baltimore, Maryland, U.S. It was founded in 1889 using money from a bequest of over $7 million (1873 mo ...
opened in 1889.
When "
the winter of 1889 or 1890" she developed a skin reaction to
mercuric chloride
Mercury(II) chloride (or mercury bichloride, mercury dichloride), historically also known as sulema or corrosive sublimate, is the inorganic chemical compound of mercury and chlorine with the formula HgCl2. It is white crystalline solid and is a ...
that was used for
asepsis
Asepsis is the state of being free from disease-causing micro-organisms (such as pathogenic bacteria, viruses, pathogenic fungi, and parasites). There are two categories of asepsis: medical and surgical. The modern day notion of asepsis is deriv ...
,
William Halsted
William Stewart Halsted, M.D. (September 23, 1852 – September 7, 1922) was an American surgeon who emphasized strict aseptic technique during surgical procedures, was an early champion of newly discovered anesthetics, and introduced several ...
, soon-to-be her husband, asked the
Goodyear Rubber Company to produce thin rubber gloves for her protection.
[ In 1894 Halsted implemented the use of sterilized medical gloves at Johns Hopkins. However, the first modern disposable glove was invented by Ansell Rubber Co. Pty. Ltd. in 1965.
They based the production on the technique for making ]condoms
A condom is a sheath-shaped barrier device used during sexual intercourse to reduce the probability of pregnancy or a sexually transmitted infection (STI). There are both male and female condoms. With proper use—and use at every act of inte ...
. These gloves have a range of clinical uses ranging from dealing with human excrement to dental applications.
Criminals have also been known to wear medical gloves during commission of crimes. These gloves are often chosen because their thinness and tight fit allow for dexterity. However, because of the thinness of these gloves, fingerprints may actually pass through the material as glove prints
Glove prints, also sometimes described as gloveprints or glove marks, are latent, fingerprint-like impressions that are transferred to a surface or object by an individual who is wearing gloves.
Many criminals often wear gloves to avoid leaving f ...
, thus transferring the wearer's prints onto the surface touched or handled.
The participants of the Watergate burglaries
The Watergate scandal was a major political scandal in the United States involving the administration of President Richard Nixon from 1972 to 1974 that led to Nixon's resignation. The scandal stemmed from the Nixon administration's contin ...
infamously wore rubber surgical gloves in an effort to hide their fingerprints.
Industry
In 2020, the market for medical gloves had a value of more than USD 10.17 billion and, with growing demand (especially in developing countries), is expected to grow by 9.2 per cent per year until 2028. The majority of medical gloves is manufactured in South East Asia with Malaysia
Malaysia ( ; ) is a country in Southeast Asia. The federation, federal constitutional monarchy consists of States and federal territories of Malaysia, thirteen states and three federal territories, separated by the South China Sea into two r ...
alone accounting for about three quarters of global production in 2020.
Labour rights violations
There have been several investigations in factories in Malaysia, Thailand
Thailand ( ), historically known as Siam () and officially the Kingdom of Thailand, is a country in Southeast Asia, located at the centre of the Indochinese Peninsula, spanning , with a population of almost 70 million. The country is bo ...
and Sri Lanka
Sri Lanka (, ; si, ශ්රී ලංකා, Śrī Laṅkā, translit-std=ISO (); ta, இலங்கை, Ilaṅkai, translit-std=ISO ()), formerly known as Ceylon and officially the Democratic Socialist Republic of Sri Lanka, is an ...
that documented severe violations of human and labour rights
Labor rights or workers' rights are both legal rights and human rights relating to labor relations between workers and employers. These rights are codified in national and international labor and employment law. In general, these rights influe ...
. Both in Malaysia and Thailand migrants represent the majority of workers in hard physical labour. They are frequently recruited by specialized agencies in their less affluent home countries such as Nepal
Nepal (; ne, नेपाल ), formerly the Federal Democratic Republic of Nepal ( ne,
सङ्घीय लोकतान्त्रिक गणतन्त्र नेपाल ), is a landlocked country in South Asia. It is mai ...
and are often charged with high recruitment fees forcing them into debt bondage
Debt bondage, also known as debt slavery, bonded labour, or peonage, is the pledge of a person's services as security for the repayment for a debt or other obligation. Where the terms of the repayment are not clearly or reasonably stated, the pe ...
. There are documented cases in which employees' passports were withheld by their employers leaving them especially vulnerable to exploitation.
In 2010, for instance, Swedwatch
Swedwatch is an independent, non-profit organization reporting on business relations in developing countries. Swedwatch is an independent research organization whose task is to critically examine business relations with developing countries focu ...
, a Swedish labour right NGO
A non-governmental organization (NGO) or non-governmental organisation (see spelling differences) is an organization that generally is formed independent from government. They are typically nonprofit entities, and many of them are active in h ...
examining a Malaysian factory, reported that most employees were working 12 hours per day seven days a week without overtime pay or payslip, harassment of workers by the management, safety deficits and poor hygienic conditions in employee housing.
Reacting to these findings, from October 2019 to March 2020, the US Department of Labor
The United States Department of Labor (DOL) is one of the executive departments of the U.S. federal government. It is responsible for the administration of federal laws governing occupational safety and health, wage and hour standards, unemploym ...
listed medical gloves produced in Malaysia on the List of Goods Produced by Child Labor or Forced Labor The ''List of Goods Produced by Child Labor or Forced Labor'' is an annual publication issued by the United States Government’s Bureau of International Labor Affairs at the U.S. Department of Labor. It has been published within the December 2014 D ...
and temporarily banned the import of gloves produced by the Malaysian company Top Glove
Top Glove Corporation Berhad is a Malaysian rubber glove manufacturer who also specialises in face masks, dental dams, and other products. The company owns and operates 50 manufacturing facilities in Malaysia, Thailand, China, and Vietnam. Th ...
, the world's largest manufacturer at the time.
Sizing
Generally speaking, examination gloves are sized in XS, S, M and L. Some brands may offer size XL. Surgical gloves are usually sized more precisely since they are worn for a much longer period of time and require exceptional dexterity. The sizing of surgical gloves are based on the measured circumference around the palm (excluding the thumb) in inch
Measuring tape with inches
The inch (symbol: in or ″) is a unit of length in the British imperial and the United States customary systems of measurement. It is equal to yard or of a foot. Derived from the Roman uncia ("twelfth") ...
es, at a level slightly above the thumb's sewn. Typical sizing ranges from 5.5 to 9.0 at an increment of 0.5. Some brands may also offer size 5.0. First-time users of surgical gloves may take some time to find the right size and brand that suit their hand geometry the most. People with a thicker palm may need a size larger than the measurement and vice versa. Sizing should be one of the first thing to look for. Dexterity is essential for every worker and wearing the wrong size of glove can have a huge impact on someone's work. Wearing the right size of glove can also increase comfort, which can influence workers to wear their assigned PPE.
Research on a group of American surgeons found that the most common surgical glove size for men is 7.0, followed by 6.5; and for women 6.0 followed by 5.5.
Powdered gloves
To facilitate donning of gloves, powders have been used as lubricants. Early powders derived from pine
A pine is any conifer tree or shrub in the genus ''Pinus'' () of the family Pinaceae. ''Pinus'' is the sole genus in the subfamily Pinoideae. The World Flora Online created by the Royal Botanic Gardens, Kew and Missouri Botanical Garden accep ...
s or club moss
Lycopodiopsida is a class of vascular plants known as lycopods, lycophytes or other terms including the component lyco-. Members of the class are also called clubmosses, firmosses, spikemosses and quillworts. They have dichotomously branching s ...
were found to be toxic. Talcum powder
Talc, or talcum, is a clay mineral, composed of hydrated magnesium silicate with the chemical formula Mg3Si4O10(OH)2. Talc in powdered form, often combined with corn starch, is used as baby powder. This mineral is used as a thickening agent ...
was used for decades but linked to postoperative granuloma
A granuloma is an aggregation of macrophages that forms in response to chronic inflammation. This occurs when the immune system attempts to isolate foreign substances that it is otherwise unable to eliminate. Such substances include infectious ...
and scar formation. Corn starch
Corn starch, maize starch, or cornflour (British English) is the starch derived from corn (maize) grain. The starch is obtained from the endosperm of the kernel. Corn starch is a common food ingredient, often used to thicken sauces or sou ...
, another agent used as lubricant, was also found to have potential side effects such as inflammatory reactions and granuloma and scar formation.[
]
Elimination of powdered medical gloves
With the availability of non-powdered medical gloves that were easy to don, calls for the elimination of powdered gloves became louder. By 2016, healthcare systems in Germany and the United Kingdom had eliminated their use.[ In March 2016, the ]United States Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food s ...
(FDA) issued a proposal to ban their medical use and on December 19, 2016 passed a rule banning all powdered gloves intended for medical use. The rule became effective on January 18, 2017.
Powder-free medical gloves are used in medical cleanroom
A cleanroom or clean room is an engineered space, which maintains a very low concentration of airborne particulates. It is well isolated, well-controlled from contamination, and actively cleansed. Such rooms are commonly needed for scientif ...
environments, where the need for cleanliness is often similar to that in a sensitive medical environment.
Chlorination
To make them easier to don without the use of powder, gloves can be treated with chlorine
Chlorine is a chemical element with the Symbol (chemistry), symbol Cl and atomic number 17. The second-lightest of the halogens, it appears between fluorine and bromine in the periodic table and its properties are mostly intermediate betwee ...
. Chlorination affects some of the beneficial properties of latex, but also reduces the quantity of allergenic latex proteins.
Polymer coating
On the market, it is a wide range of applications for polymer coatings in the market. Most of the current disposable gloves are powered. These coatings include several polymers: silicone, acrylic resins, and gels that make gloves easier to wear. This process is currently used in nitrile gloves and latex gloves.
Alternatives to latex
Due to the increasing rate of latex allergy among health professionals , and in the general population, gloves made of non-latex materials such as polyvinyl chloride, nitrile rubber
Nitrile rubber, also known as nitrile butadiene rubber, NBR, Buna-N, and acrylonitrile butadiene rubber, is a synthetic rubber derived from acrylonitrile (ACN) and butadiene. Trade names include Perbunan, Nipol, Krynac and Europrene. This rubber is ...
, or neoprene
Neoprene (also polychloroprene) is a family of synthetic rubbers that are produced by polymerization of chloroprene.Werner Obrecht, Jean-Pierre Lambert, Michael Happ, Christiane Oppenheimer-Stix, John Dunn and Ralf Krüger "Rubber, 4. Emulsion R ...
have become widely used. Chemical processes may be employed to reduce the amount of antigenic protein in Hevea
''Hevea'' is a genus of flowering plants in the spurge family, Euphorbiaceae, with about ten members. It is also one of many names used commercially for the wood of the most economically important rubber tree, '' H. brasiliensis''. The genus is n ...
latex, resulting in alternative natural-rubber-based materials such Vytex Natural Rubber Latex Vytex Natural Rubber Latex (NRL) is a brand of natural rubber latex produced and marketed by Vystar Corporation. Vytex NRL is an alternative material to petroleum-based synthetics and traditional, or Hevea, natural rubber latex. Protein test resu ...
. However, non-latex gloves have not yet replaced latex gloves in surgical procedures, as gloves made of alternative materials generally do not fully match the fine control or greater sensitivity to touch available with latex surgical gloves. (High-grade isoprene
Isoprene, or 2-methyl-1,3-butadiene, is a common volatile organic compound with the formula CH2=C(CH3)−CH=CH2. In its pure form it is a colorless volatile liquid. Isoprene is an unsaturated hydrocarbon. It is produced by many plants and animals ...
gloves are the only exception to this rule, as they have the same chemical structure as natural latex rubber. However, fully artificial polyisoprene—rather than "hypoallergenic
Hypoallergenic, meaning "below average" or "slightly" allergenic, is a term meaning that something (usually cosmetics, pets, textiles, food, etc.) causes fewer allergic reactions. The term was first used in 1953 in an advertising campaign for cosm ...
" cleaned natural latex rubber—is also the most expensive natural latex substitute available.) Other high-grade non-latex gloves, such as nitrile gloves, can cost over twice the price of their latex counterparts, a fact that has often prevented switching to these alternative materials in cost-sensitive environments, such as many hospitals. Nitrile is more resistant to tearing than natural latex, and is more resistant to many chemicals. Sulfur compounds used as accelerants to cure nitrile can speed the tarnishing process in silver, so accelerant-free nitrile or other gloves must be used when handling objects made of these metals when this is not acceptable.
Double gloving
Double gloving is the practice of wearing two layers of medical gloves to reduce the danger of infection from glove failure or penetration of the gloves by sharp objects during medical procedures. Surgeons double glove when operating on individuals bearing infectious agents such as HIV
The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
and hepatitis
Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), poor appetite, vomiting, tiredness, abdominal pa ...
, and to better protect patients against infections possibly transmitted by the surgeon. A systematic review of the literature has shown double gloving to offer significantly more protection against inner glove perforation in surgical procedures compared to the use of a single glove layer. But it was unclear if there was better protection against infections transmitted by the surgeon. Another systematic review studied if double gloving protected the surgeon better against infections transmitted by the patient. Pooled results of 12 studies (RCTs) with 3,437 participants showed that double gloving reduced the number of perforations in inner gloves with 71% compared to single gloving. On average ten surgeons/nurses involved in 100 operations sustain 172 single gloves perforations but with double gloves only 50 inner gloves would be perforated. This is a considerable reduction of the risk.
In addition, cotton gloves can be worn under the single-use gloves to reduce the amount of sweat produced when wearing these gloves for a long period of time. These under gloves can be disinfected and used again.
References
{{Laboratory equipment
First aid
Gloves
Medical hygiene
Safety clothing
glove