Medicinal uses
''Pentanema brittanica'' is used in Chinese Herbalism by harvesting and drying the flower. It has been used to treat sputum, as the Chinese found it to be beneficial when phlegm has accumulated in the bronchi. Other symptoms in which it has been found to be a clinical remedy for are nausea, vomiting, hiccups, and flatulence. The severity of the condition determines what part of the plant is used; if the symptoms are mild, the leaves are used, whereas more severe cases require use of the flowers. A multitude of different chemical constituents have been isolated from ''Pentanema britannica''. Some of the chemical constituents include steroids, terpenoids, phenolics and flavonoids. The majority of these compounds are found in the flowers and have been found to have anticancer, antioxidant, anti-inflammatory, neuroprotective and hepatoprotective properties. ''Pentanema britannica'' has pharmacological potential.Origin and current distribution
''Pentanema brittanica'' is native to regions of Europe and Asia and was first observed in North America after introduction to Ontario, Canada in 1928 and observation in Long Island, New York before 1915. Following the introduction of ''Pentanema brittanica'' in New York, it was then introduced to Michigan in 1990, Minnesota in 2004, and Oregon in 2002. The current distribution of this species is extensive and includes a multitude of countries spanning several continents. In Europe, this includes Albania, Austria, Belgium, Bulgaria, Czech Republic, Slovakia, Denmark, Finland, France, Germany, Greece, Hungary, Italy, Luxembourg, Netherlands, Norway, Poland, Romania, Russia/USSR (Northern Region, Baltic Region, Central Region, Southwestern Region, Crimea, Southeastern Region), Spain, Sweden, Switzerland, Turkey (European part), and Yugoslavia. In Asia, this includes China (North and Northeastern), Korea, Iran, Armenia, Kurdistan, Dzhyuungaria-Kashgaria, Mongolia, USSR (Eastern Siberia, Far East, Soviet Central Asia), and several of the Japanese islands (Hokkaido, Honshu, Shikoku, and Kyushu). In North America, this includes Canada (Ontario and Quebec) and the United States (New York, Michigan, Minnesota, and Oregon).Modes of distribution
Several modes of distribution have been identified for being responsible for the spread of ''P. brittanica''. These include contaminated plant parts (specifically hostas), wind, and locally on machinery within plant nurseries. An example of this was how it was discovered in November 1999 within a west Michigan nursery and was found difficult to control after being accidentally imported with Dutch hosta plants. Furthermore, due to its known medicinal uses, ''I. brittanica'' may also be transported via humans within passenger baggage.Characteristics as an invasive species
Observations of ''Pentanema brittanica'' in various new habitats have led to conclusions that it is capable of thriving in a wide range of temperatures as well as climates, indicated by its presence in Sweden and eastern North America, respectively. A limiting (and, thus influential) factor of the successful establishment of ''P. brittanica'' in new habitats is moisture, with higher moisture levels corresponding to a higher level of invasibility. Furthermore, this species was suspected to have been introduced without any natural enemies, which also has been speculated to contribute to its success as an invasive species Within its original habitat as well as new ones, ''P. brittanica'' is known to infest nursery crops, specifically hostas (also known as plantain lilies) in the Netherlands where their roots and rhizomes become intertwined with the hosta root systems. Specifically, root fragments of ''P. britannica'' are known to enter under bulb scales. Once intertwined, this plant is aggressive and hard to remove, and can remain even after the infested hosta roots are washed. The overall impact of this species is that it is harmful, as upon infestation, ''P. brittanica'' impedes hostas from retrieving valuable nutrients from the soil. It has been identified as posing a threat to the environments that it invades due to having the potential to cause damage to invaded plant ecosystems and loss of native plant life. Additionally, economic risks have been weighed and taken into consideration, and it has been determined to pose a large one due to the wide range of habitats that it can invade and environmental damage it is capable of causing.Intervention and control measures
Some of the first recommendations for controlling ''P. brittanica'' when it was discovered in Michigan nurseries involved methods of both chemical and mechanical control. It was proposed that, from a mechanical standpoint, deep plowing or cultivation was effective, while Roundup was an effective chemical method of control. When using Roundup, one can be strategic in targeting the “mother plant” of ''P. brittanica'', which is known to connect to a network of smaller satellite weeds connected by a network of rhizomes. Thus, by targeting the mother plant, the satellites can be effectively eliminated while using a minimal amount of the herbicide. A lesser-known form of control is biologic methods, in which known predators (pests) of ''I. brittanica'' are deployed to consume the weed. One such predator is the moth ''Hellinsia inulae''. There is not much information on the current status of mitigation efforts to control ''P. brittanica''. After detection in its hosta nurseries in 1990, Michigan made efforts to restrict the movement, distribution, and sale of the infested hostas to prevent further spread. It was not until four years later that the Dutch placed ''P. brittanica'' on their noxious weed list and began taking aggressive measures to treat infested fields and reject them from export as applicable.2007 WSSA Committee Report to Members. Weed Society of America, 2007, wssa.net/wp-content/uploads/2008CR_Weed-Alert.pdfReferences
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