Masiello is a surname originating in Italy. Notable people with the surname include:
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Andrea Masiello (born 1986), Italian soccer player
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Anthony Masiello, Buffalo, New York, politician
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Luciano Masiello (born 1952), Italian-born English and Irish soccer player
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Salvatore Masiello (born 1982), Italian soccer player
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Wendy M. Masiello, United States Air Force officer
{{surname, Masiello
Italian-language surnames