Maryam Shanechi
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Maryam M. Shanechi is an Iran-born
American American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, pe ...
neuroengineer. She studies ways of decoding the brain's activity to control brain-machine interfaces. She was honored as one of
MIT Technology Review ''MIT Technology Review'' is a bimonthly magazine wholly owned by the Massachusetts Institute of Technology, and editorially independent of the university. It was founded in 1899 as ''The Technology Review'', and was re-launched without "The" in ...
's Innovators under 35 in 2014 and one of the
Science News ''Science News (SN)'' is an American bi-weekly magazine devoted to articles about new scientific and technical developments, typically gleaned from recent scientific and technical journals. History ''Science News'' has been published since 1 ...
10 scientists to watch in 2019. She is Professor and Viterbi Early Career Chair in Electrical and Computer Engineering at the
Viterbi School of Engineering The USC Viterbi School of Engineering (formerly the USC School of Engineering) is the engineering school of the University of Southern California. It was renamed following a $52 million donation by Andrew J. Viterbi, co-founder of Qualcomm. ...
, and a member of the Neuroscience Graduate Program at the
University of Southern California The University of Southern California (USC, SC, or Southern Cal) is a Private university, private research university in Los Angeles, California, United States. Founded in 1880 by Robert M. Widney, it is the oldest private research university in C ...
.


Early life and career

Shanechi was born in
Iran Iran, officially the Islamic Republic of Iran, and also called Persia, is a country located in Western Asia. It is bordered by Iraq and Turkey to the west, by Azerbaijan and Armenia to the northwest, by the Caspian Sea and Turkmeni ...
and moved to Canada with her family when she was 16. She received her bachelor's degree in engineering from the
University of Toronto The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution ...
in 2004. She then moved to
MIT The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the mo ...
, where she completed her master's degree in electrical engineering and computer science in 2006 and her PhD in 2011. She completed a postdoc at Harvard Medical School before moving to the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...
, in 2012. She held a faculty position at Cornell University, before moving to the
University of Southern California The University of Southern California (USC, SC, or Southern Cal) is a Private university, private research university in Los Angeles, California, United States. Founded in 1880 by Robert M. Widney, it is the oldest private research university in C ...
, where she is currently a Professor and Viterbi Early Career Chair within the
USC Viterbi School of Engineering The USC Viterbi School of Engineering (formerly the USC School of Engineering) is the engineering school of the University of Southern California. It was renamed following a $52 million donation by Andrew J. Viterbi, co-founder of Qualcomm. W ...
.


Research

While pursuing her graduate degree at MIT, Shanechi became interested in decoding the brain, the idea of reading out the original meaning from brain signals. She developed an algorithm to determine where a monkey wanted to point the cursor on a screen based on the animal's brain activity. She later improved upon her work by including high-rate decoding, meaning the decoding happened over a few milliseconds, rather than every 100 milliseconds, which is the standard for traditional methods. More recently, th
Shanechi Lab
has developed novel methods that can dissociate those dynamics in neural activity that are most predictive of behavior and can significantly improve decoding. Her lab has also developed methods that can simultaneously use multiple spatiotemporal scales of neural measurements to model their relationships and improve decoding. In 2013, she developed a brain decoding method that could help automatically control the amount of
anesthesia Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), ...
that is to be administered to a patient. Her team, which included colleagues from
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...
and
Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ...
was able to control the depth of the
medically-induced coma An induced comaalso known as a medically induced coma (MIC), barbiturate-induced coma, or drug-induced comais a temporary coma (a deep state of unconsciousness) brought on by a controlled dose of an anesthetic drug, often a barbiturate such as ...
in rodents automatically based on their brain activity. Shanechi is also interested in the application of neural decoding algorithms to psychiatric disorders, such as
PTSD Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder that can develop because of exposure to a traumatic event, such as sexual assault, warfare, traffic collisions, child abuse, domestic violence, or other threats on a ...
and depression. Her research team developed a method to decipher the mood of a person from their brain activity. They measured the brain activity of seven patients who had electrodes implanted in their brain to monitor
epilepsy Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical ...
. The patients answered questions about their mood while the electrodes were implanted. Using the data about the mood and the brain activity, Shanechi's lab was able to match the two together and decipher which brain activity was related to which mood. The paper on this work was awarded the 3rd prize in the International BCI Awards. Her lab has also developed a stochastic stimulation and modeling approach that can predict the response of multi-regional brain networks implicated in neuropsychiatric disorders to ongoing deep brain stimulation (DBS). In the future, Shanechi wants to develop these techniques in order to stimulate the brain automatically when a change in mood is detected.


Awards

*
NIH Director's New Innovator Award National Institutes of Health Director's New Innovator Award is a research initiative first announced in 2007 designed to supports exceptionally creative, early-career investigators who propose innovative, high-impact projects. The focus is specif ...
, 2020 *
Science News ''Science News (SN)'' is an American bi-weekly magazine devoted to articles about new scientific and technical developments, typically gleaned from recent scientific and technical journals. History ''Science News'' has been published since 1 ...
10 Scientists to Watch, 2019 *
Popular Science ''Popular Science'' (also known as ''PopSci'') is an American digital magazine carrying popular science content, which refers to articles for the general reader on science and technology subjects. ''Popular Science'' has won over 58 awards, incl ...
Brilliant 10, 2015 *
MIT Technology Review ''MIT Technology Review'' is a bimonthly magazine wholly owned by the Massachusetts Institute of Technology, and editorially independent of the university. It was founded in 1899 as ''The Technology Review'', and was re-launched without "The" in ...
Innovators Under 35, 2014 *
NSF CAREER Award The National Science Foundation CAREER awards, presented by the National Science Foundation (NSF), are in support of junior faculty who exemplify the role of teacher-scholars through research and education, and the integration of these endeavors i ...
, 2015 *
Office of Naval Research The Office of Naval Research (ONR) is an organization within the United States Department of the Navy responsible for the science and technology programs of the U.S. Navy and Marine Corps. Established by Congress in 1946, its mission is to plan ...
Young Investigator Award, 2019 *
American Society for Engineering Education The American Society for Engineering Education (ASEE) is a non-profit member association, founded in 1893, dedicated to promoting and improving engineering and engineering technology education. The purpose of ASEE is the advancement of education ...
(ASEE) Curtis W. McGraw Research Award, 2021 *Multidisciplinary University Research Initiative (MURI) Award, 2016 *Mid-Career Achievement Award, University of Toronto Engineering, 2019
One Mind Rising Star Award
2022


Selected publications

Shanechi's publications include: * * * * * * * *


References

{{DEFAULTSORT:Shanechi, Maryam 1981 births Living people American neuroscientists American women neuroscientists University of Southern California faculty Iranian emigrants to the United States University of Toronto alumni Massachusetts Institute of Technology alumni American electrical engineers American women engineers