Mary Logan Reddick
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Mary Logan Reddick (31 December 1914 – 1 October 1966) was an American neuroembryologist who earned her PhD from
Radcliffe College Radcliffe College was a women's liberal arts college in Cambridge, Massachusetts, and functioned as the female coordinate institution for the all-male Harvard College. Considered founded in 1879, it was one of the Seven Sisters colleges and he ...
,
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
in 1944. She was a full professor, first at
Morehouse College , mottoeng = And there was light (literal translation of Latin itself translated from Hebrew: "And light was made") , type = Private historically black men's liberal arts college , academic_affiliations ...
, and then at the
University of Atlanta The University of Atlanta was a Private university, private, For-profit higher education in the United States, for-profit, distance education university headquartered in Atlanta, Georgia. It opened in Mobile, Alabama as Barrington University u ...
from 1953 to her death. Her doctoral dissertation was on the study of chick embryos, and she went on to do research with
time-lapse microscopy Time-lapse microscopy is time-lapse photography applied to microscopy. Microscope image sequences are recorded and then viewed at a greater speed to give an accelerated view of the microscopic process. Before the introduction of the video tape ...
(then called motion picture microphotography) in tissue cultures. In 1952, Reddick received a Ford science fellowship to study at
Cambridge University , mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Schola ...
. Reddick was possibly the first African-American woman scientist to receive this fellowship for study abroad, and she was the first female biology instructor at
Morehouse College , mottoeng = And there was light (literal translation of Latin itself translated from Hebrew: "And light was made") , type = Private historically black men's liberal arts college , academic_affiliations ...
.


Early life and education

Mary Reddick was born in
Atlanta Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 ...
, Georgia in 1914. She graduated from the Laboratory High School and started majoring in biology at Spelman College in 1929 at the age of 15. Spelman is a women's
historically black college Historically black colleges and universities (HBCUs) are institutions of higher education in the United States that were established before the Civil Rights Act of 1964 with the intention of primarily serving the African-American community. Mo ...
, affiliated with the University of Atlanta and
Morehouse College , mottoeng = And there was light (literal translation of Latin itself translated from Hebrew: "And light was made") , type = Private historically black men's liberal arts college , academic_affiliations ...
. This affiliation enabled her to study with an African-American scientist at Morehouse, Samuel Milton Nabrit. Her senior faculty at Spelman were both white female biologists. Reddick assisted in labs for four years after completing her bachelor's degree in science at Spelman. She was awarded her bachelor's degree in 1935. In 1937, she received a
Rockefeller Foundation The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, after the Carneg ...
General Education Board Fellowship, enabling her to gain a Masters of Science degree from the University of Atlanta, with a thesis studying the embryo chick
blastoderm A blastoderm (germinal disc, blastodisc) is a single layer of embryonic epithelial tissue that makes up the blastula. It encloses the fluid filled blastocoel. Gastrulation follows blastoderm formation, where the tips of the blastoderm begins the for ...
.


Career and postgraduate education

After gaining her Masters, Reddick began teaching biology at Spelman in 1937. She became the first female biology instructor at Morehouse College in 1939. In 1942, Reddick was awarded a second Rockefeller education fellowship by
Radcliffe College Radcliffe College was a women's liberal arts college in Cambridge, Massachusetts, and functioned as the female coordinate institution for the all-male Harvard College. Considered founded in 1879, it was one of the Seven Sisters colleges and he ...
, the women's coordinate for
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
at that time. Reddick studied techniques for transplanting tissues and nerve cell differentiation in chick embryos there for two years, gaining a second master's degree in biology in 1943 and being awarded a PhD in 1944. Her doctoral dissertation was titled ''The differentiation of embryonic chick medulla in chorioallantoic grafts''. She was elected to the
Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal a ...
and Sigma Xi honor societies.
Geraldine Pittman Woods Geraldine Pittman Woods (January 29, 1921 – December 27, 1999) was an American science administrator. She is known for her lifelong dedication to community service and for establishing programs that promote minorities in STEM fields, scientif ...
was a classmate. Reddick was the 10th member of Morehouse faculty to earn a doctorate. Reddick returned to Morehouse, and became the first female to act as chair of the biology department, later promoted to full professor. In 1952, Reddick was possibly the first African-American woman to receive a Ford Foundation science fellowship to study abroad, studying embryology at the School of Anatomy at
Cambridge University , mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Schola ...
. She returned to the US in 1953, and joined the faculty at the University of Atlanta, with the rank of full professor and named chair of the biology department. During the 1950s and 1960s she supervised the research of more than 20 students, including
Luther Williams Luther may refer to: People * Martin Luther (1483–1546), German monk credited with initiating the Protestant Reformation * Martin Luther King Jr. (1929-1968), American minister and leader in the American civil rights movement * Luther (gi ...
. She also gained a research grant from the
National Science Foundation The National Science Foundation (NSF) is an independent agency of the United States government that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National I ...
. She held the position of Professor there until her death at the age of 51 in 1966.


Embryological research

Reddick began her
embryogenesis An embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm ...
studies using the developing
chicken The chicken (''Gallus gallus domesticus'') is a domesticated junglefowl species, with attributes of wild species such as the grey and the Ceylon junglefowl that are originally from Southeastern Asia. Rooster or cock is a term for an adult m ...
embryo An embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male spe ...
, specifically White Leghorns and
Rhode Island Red The Rhode Island Red is an American breed of domestic chicken. It is the state bird of Rhode Island. It was developed there and in Massachusetts in the late nineteenth century, by cross-breeding birds of Oriental origin such as the Malay with ...
s. The larger question she addressed was what the developmental potential was of portions of the early chick
blastoderm A blastoderm (germinal disc, blastodisc) is a single layer of embryonic epithelial tissue that makes up the blastula. It encloses the fluid filled blastocoel. Gastrulation follows blastoderm formation, where the tips of the blastoderm begins the for ...
, when transplanted to the chorioallantoic membrane of a
chick Chick or chicks may refer to: *Chick (young bird), a bird that has not yet reached adulthood People * Chick (nickname), a list of people * Chick (surname), various people * Chick McGee, stage name of radio personality Charles Dean Hayes (born 19 ...
in a later stage of development, in "cut-and-paste" experiments. These "cut-and-paste" experiments supported the hypothesis that the
node In general, a node is a localized swelling (a "knot") or a point of intersection (a vertex). Node may refer to: In mathematics *Vertex (graph theory), a vertex in a mathematical graph *Vertex (geometry), a point where two or more curves, lines, ...
is
necessary and sufficient In logic and mathematics, necessity and sufficiency are terms used to describe a conditional or implicational relationship between two statements. For example, in the conditional statement: "If then ", is necessary for , because the truth of ...
for specifying differentiation of many derivatives of
ectoderm The ectoderm is one of the three primary germ layers formed in early embryonic development. It is the outermost layer, and is superficial to the mesoderm (the middle layer) and endoderm (the innermost layer). It emerges and originates from t ...
,
mesoderm The mesoderm is the middle layer of the three germ layers that develops during gastrulation in the very early development of the embryo of most animals. The outer layer is the ectoderm, and the inner layer is the endoderm.Langman's Medical E ...
, and
endoderm Endoderm is the innermost of the three primary germ layers in the very early embryo. The other two layers are the ectoderm (outside layer) and mesoderm (middle layer). Cells migrating inward along the archenteron form the inner layer of the gast ...
, but not all. For instance, any cases of liver tissue development that she observed only occurred where there was heart tissue nearby. For her dissertation work at Radcliffe, Reddick studied
neurodevelopment The development of the nervous system in humans, or neural development or neurodevelopment involves the studies of embryology, developmental biology, and neuroscience to describe the cellular and molecular mechanisms by which the complex nervous ...
of the chick medulla. For these experiments, she used embryos from Plymouth Rock chickens. The goal of her experiments was to understand how much of that area of the brain was already determined and how much was dependent on interactions with surrounding developing tissues, such as
notochord In anatomy, the notochord is a flexible rod which is similar in structure to the stiffer cartilage. If a species has a notochord at any stage of its life cycle (along with 4 other features), it is, by definition, a chordate. The notochord consis ...
, somites, and
ectoderm The ectoderm is one of the three primary germ layers formed in early embryonic development. It is the outermost layer, and is superficial to the mesoderm (the middle layer) and endoderm (the innermost layer). It emerges and originates from t ...
. The results of these experiments supported the hypothesis that while some aspects of the post-otic medulla in chick have already been determined, there needs to be a continuous interaction with surrounding developing tissues. Subsequent work addressed several technical problems in assessing cell differentiation. For these experiments, Reddick used White Plymouth Rock chicken embryos. One of the questions she addressed was whether nerve cells in the post- otic chick medulla became
syncytial A syncytium (; plural syncytia; from Greek: σύν ''syn'' "together" and κύτος ''kytos'' "box, i.e. cell") or symplasm is a multinucleate cell which can result from multiple cell fusions of uninuclear cells (i.e., cells with a single nucleus) ...
during development. To try to get single developing
nerve cells A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. No ...
with long processes visible in one plane of focus under the
microscope A microscope () is a laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic means being invisibl ...
, Reddick used a "smear" technique of flattening tissue before
fixing Fixing may refer to: * The present participle of the verb "to fix", an action meaning maintenance, repair, and operations * "fixing someone up" in the context of arranging or finding a social date for someone * "Fixing", craving an addictive drug, ...
and
staining Staining is a technique used to enhance contrast in samples, generally at the microscopic level. Stains and dyes are frequently used in histology (microscopic study of biological tissues), in cytology (microscopic study of cells), and in the ...
it. She also found that what had been thought of as two different cell types, was actually one cell type in different phases of the
cell cycle The cell cycle, or cell-division cycle, is the series of events that take place in a cell that cause it to divide into two daughter cells. These events include the duplication of its DNA (DNA replication) and some of its organelles, and subs ...
. Some of the cells were mitotic, and others were in the interphase.


Publications

* Reddick ML (1937). ''The differentiation of portions of the chick blastoderm in chorio-allantoic grafts''. Thesis for Degree of the Masters of Science, University of Atlanta. * Reddick ML (1944). ''The differentiation of embryo chick medulla in chorioallantoic grafts.'' Dissertation, Radcliffe College, Harvard University. * Reddick ML (1945). The differentiation of embryonic chick medulla in chorioallantoic grafts. ''Journal of Comparative Neurology''. * Reddick ML (1951). Histogenesis of the cellular elements in the postotic medulla of the chick embryo. ''The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology''.


References

{{DEFAULTSORT:Reddick, Mary Logan 1914 births African-American women scientists NIH Women Scientists Project 20th-century American women scientists American women biologists Radcliffe College alumni 1966 deaths 20th-century African-American women 20th-century African-American scientists