Mary Frances Earley Klotman (born 1954) is an American physician-scientist and academic administrator. She was elected as a member of the National Academy of Medicine in 2014 and became the

editor Editing is the process of selecting and preparing written, photographic, visual, audible, or cinematic material used by a person or an entity to convey a message or information. The editing process can involve correction, condensation, orga ...

of the ''

Annual Review of Medicine The ''Annual Review of Medicine'' is a peer-reviewed medical journal that publishes review articles about all aspects of medicine. It was established in 1950. Its longest-serving editors have been William P. Creger (1974–1993) and C. Thomas Ca ...

'' in 2020. She has been the dean of the

Duke University School of Medicine The Duke University School of Medicine, commonly known as Duke Med, is the medical school of Duke University. It is located in the Collegiate Gothic-style West Campus of Duke University in Durham, North Carolina. The School of Medicine, along wit ...

since 2017.

Early life and education

Mary Frances Earley was born in 1954 in

Long Island Long Island is a densely populated island in the southeastern region of the U.S. state of New York (state), New York, part of the New York metropolitan area. With over 8 million people, Long Island is the most populous island in the United Sta ...

to parents Jean and Anthony Earley. She was one of six children in her family. Her father worked in the

textile industry The textile industry is primarily concerned with the design, production and distribution of yarn, cloth and clothing. The raw material may be natural, or synthetic using products of the chemical industry. Industry process Cotton manufacturi ...

and frequently traveled for his job, including to North Carolina. Mary accompanied him on one such trip to

Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...

, where she says she "fell in love" with the campus. Mary Earley attended Duke University for both her

bachelor's degree A bachelor's degree (from Middle Latin ''baccalaureus'') or baccalaureate (from Modern Latin ''baccalaureatus'') is an undergraduate academic degree awarded by colleges and universities upon completion of a course of study lasting three to six ...

in zoology and

Doctor of Medicine Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a profes ...

Career

Klotman has spent most of her research career studying the

HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...

, particularly its effect on the

kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood ...

s ( HIV-associated nephropathy). After graduating with her MD, Klotman stayed at Duke to complete a residency in internal medicine and a fellowship in infectious disease. She was then an associate professor of medicine. In 1991, she joined the

National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...

where she researched HIV with

Robert Gallo Robert Charles Gallo (; born March 23, 1937) is an American biomedical researcher. He is best known for his role in establishing the human immunodeficiency virus (HIV) as the infectious agent responsible for acquired immune deficiency syndrome ( ...

. She then worked at the

Icahn School of Medicine at Mount Sinai The Icahn School of Medicine at Mount Sinai (ISMMS or Mount Sinai), formerly the Mount Sinai School of Medicine, is a private medical school in New York City. It is the academic teaching arm of the Mount Sinai Health System, which manages eight ...

as the Irene and Dr. Arthur M. Fishberg Professor of Medicine, chief of the Division of Infectious Diseases, and co-director of its Global Health and Emerging Pathogens Institute. She returned to Duke in 2010 as the chair of its department of medicine and as the R.J. Reynolds Professor of Medicine. She taught pathology, microbiology, and molecular genetics. In 2017, she succeeded Nancy Andrews as the dean of the Duke University School of Medicine. She also became the vice chancellor for health affairs. In 2020, she succeeded C. Thomas Caskey as the

of the ''

''. She was a finalist to serve as director of the NIH in 2022 before withdrawing from consideration.

Awards and honors

Klotman was elected to the National Academy of Medicine in 2014. She received a Duke University School of Medicine Distinguished Alumni Award in 2015. She was formerly the president of the Association of American Physicians, Association of Professors of Medicine, and Duke Medical Alumni Association. She

Personal life

Mary Klotman is married to Paul Klotman whom she met while both were students at the

. They married at the Duke Chapel on November 28, 1981. As Mary is Catholic and Paul is Jewish, their minister was Unitarian Universalist, as they could not find a rabbi nor priest willing to marry them. The Klotmans have two sons, one of whom was the first born via

in vitro fertilization In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) ...

at Duke University.

References

{{DEFAULTSORT:Klotman, Mary E 1954 births Living people Duke University alumni Duke University School of Medicine alumni Icahn School of Medicine at Mount Sinai faculty Duke University School of Medicine faculty National Institutes of Health people Physician-scientists Annual Reviews (publisher) editors American medical researchers American women medical researchers 21st-century American women physicians 21st-century American physicians Members of the National Academy of Medicine