Martin J. Tobin
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Martin John Tobin (born 23 April 1951) is an
Irish-American , image = Irish ancestry in the USA 2018; Where Irish eyes are Smiling.png , image_caption = Irish Americans, % of population by state , caption = Notable Irish Americans , population = 36,115,472 (10.9%) alone ...
critical care physician,
pulmonologist Pulmonology (, , from Latin ''pulmō, -ōnis'' "lung" and the Greek suffix "study of"), pneumology (, built on Greek πνεύμων "lung") or pneumonology () is a medical specialty that deals with diseases involving the respiratory tract.
, and academic who is a recognised expert in acute respiratory failure,
mechanical ventilation Mechanical ventilation, assisted ventilation or intermittent mandatory ventilation (IMV), is the medical term for using a machine called a ventilator to fully or partially provide artificial ventilation. Mechanical ventilation helps move a ...
, and neuromuscular control of breathing. According to the
American Thoracic Society The American Thoracic Society (ATS) is a nonprofit organization focused on improving care for pulmonary diseases, critical illnesses and sleep-related breathing disorders. It was established in 1905 as the American Sanatorium Association, and ...
, Tobin is "the supreme scholar of critical care medicine and editor or author of seven extraordinary textbooks on the subject." ''
The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, ...
'' described his textbook ''Principles And Practice of Mechanical Ventilation'' as the "Bible" of the field of mechanical ventilation. He was elected to the
American Society for Clinical Investigation The American Society for Clinical Investigation (ASCI), established in 1908, is one of the oldest and most respected medical honor societies in the United States. Organization and purpose The ASCI is an honorary society to which more than 2,800 ph ...
in 1994 and was editor of the ''
American Journal of Respiratory and Critical Care Medicine The ''American Journal of Respiratory and Critical Care Medicine'' is a biweekly peer-reviewed medical journal published by the American Thoracic Society. It covers the pathophysiology and treatment of diseases that affect the respiratory system, ...
'' from 1999–2004.


Education and career

Tobin was born in
Freshford, County Kilkenny Freshford () is a village and former town in the barony of Crannagh, County Kilkenny, Ireland. History The village is the site of a monastery dating to the early 7th century. The Irish name ''achadh úr'' has historically been anglicised as '' ...
, and attended medical school at University College Dublin (1969-1975) and where he earned a MB BCh BAO. He earned a British Thoracic Association Research Fellowship at
King's College Hospital King's College Hospital is a major teaching hospital and major trauma centre in Denmark Hill, Camberwell in the London Borough of Lambeth, referred to locally and by staff simply as "King's" or abbreviated internally to "KCH". It is managed b ...
, London with Philip Hugh-Jones. He was a pulmonary fellow in the Division of Pulmonary Medicine at the
University of Miami The University of Miami (UM, UMiami, Miami, U of M, and The U) is a private research university in Coral Gables, Florida. , the university enrolled 19,096 students in 12 colleges and schools across nearly 350 academic majors and programs, i ...
from 1980 to 1982, and then served as a critical care fellow at the
University of Pittsburgh The University of Pittsburgh (Pitt) is a public state-related research university in Pittsburgh, Pennsylvania. The university is composed of 17 undergraduate and graduate schools and colleges at its urban Pittsburgh campus, home to the univers ...
. He joined the faculty at the
University of Texas Health Science Center at Houston The University of Texas Health Science Center at Houston (UTHealth) is a public academic health science center in Houston, Texas, United States. It was created in 1972 by The University of Texas System Board of Regents. It is located in the T ...
in 1990. The following year he became Professor of Medicine and Anesthesiology at Loyola University Chicago. Tobin is a pulmonologist at
Edward Hines Jr. Veterans Administration Hospital The Edward Hines Jr. Veterans Administration Hospital is a second-generation Veterans Health Administration hospital in Hines, Illinois, United States. It currently encompasses on its campus and leases an additional to the Loyola University Medi ...
and
Loyola University Medical Center Loyola Medicine, also known as Loyola University Health System, is a quaternary-care system with a main medical center campus in the western suburbs of Chicago, in the U.S. state of Illinois. The medical center campus is located in Maywood, ...
near Chicago. Dr. Martin J. Tobin (MB BCh BAO 1975) is the recipient of the 2022 UCD Alumni Award in Research, Innovation and Impact


Rapid shallow breathing index

In 1991, Tobin and Karl L. Yang published a study that described two new indices, the rapid shallow breathing index (RSBI) – initially known as the Yang Tobin Index (Y/T) – and the compliance, respiratory rate, oxygenation, and maximal inspiratory pressure (CROP) index.


''State v. Chauvin''

In April 2021, Tobin was an expert witness for the prosecution at '' State v. Chauvin'', the criminal trial against former police officer Derek Chauvin, who murdered George Floyd in
Minneapolis Minneapolis () is the largest city in Minnesota, United States, and the county seat of Hennepin County. The city is abundant in water, with thirteen lakes, wetlands, the Mississippi River, creeks and waterfalls. Minneapolis has its origins ...
in May 2020. Tobin testified that Floyd's immediate cause of death was low levels of oxygen resulting from three factors: being held in a semi-prone position on a paved street, the pressure of Officer Chauvin's knee and body on his neck and back, and his handcuffed left hand being pressed into his back. Tobin stated, the knee on Floyd’s neck was compressing his hypopharynx. Tobin testified that the hypopharynx is very important but extremely small to breathe through, has no cartilage around it, which makes it vulnerable to occlusion. Tobin indicated positions in which Chauvin compressed Floyd's hypopharynx, exerting greater force on it. Tobin testified he can calculate the amount of the force, narrowing in the space that people breathe through and difficulty of breathing. Exhibit named ‘Effect of Airway narrowing on Patient Effort to Breathe’ was presented.  Exhibit contained the plot with efforts to breathe/ΔP outlet-inlet (Pa) on vertical axis, flow rate (L/min) on the horizontal axis and curves for different percentage of airway narrowing. Tobin explained that 60% narrowing produces no noticeable effect on breathing, it is only at 85% narrowing the curve abruptly takes off.  Tobin testified the plot reflected physiological experiment.  He said: ‘This is the science behind that plot.’ As footnote indicated, the plot was extracted from the article ‘Tracheal stenosis: a flow dynamics study’ by  Mark Brouns, Santhosh T. Jayaraju, Chris Lacor, Johan De Mey, Marc Noppen, Walter Vincken, and Sylvia Verbanck, Journal of Applied Physiology 102: 1178– 1184, 2007. The authors of the article search for a way to detect tracheal stenosis on the early stage. They made computer simulation by artificially inserting tracheal stenosis into a realistic three-dimensional upper airway model derived from multislice computed tomography images of healthy men. They assessed flow patterns and pressure drops over tracheal stenosis in such artificial model. No experiment was held, no narrowing of the hypopharynx was considered in the article. Tobin testified again that Mr Chauvin’s knee on Mr Floyd’s neck caused the narrowing of Mr Floyd’s hypopharynx. Earlier Tobin stated that the calculations (of difficulty of breathing) are true for anybody with this level of narrowing.  He never testified what narrowing of hypopharynx or airway Floyd suffered as a result of Chauvin’s pressure. He only stated that breathing with such narrowing is akin to breathing through a drinking straw, but much worse, and we know this from physics. He also testified that
fentanyl Fentanyl, also spelled fentanil, is a very potent synthetic opioid used as a pain medication. Together with other drugs, fentanyl is used for anesthesia. It is also used illicitly as a recreational drug, sometimes mixed with heroin, cocain ...
detected in his system at a level of 11 ng/ml, while elevated, had not factored in his death. He additionally explained, with the help of still photos of the incident, how Floyd seemed to use various bodily maneuvers to attempt to breathe. He also stated that fentanyl overdose would have slowed Floyd’s breathing to below the normal rate, demonstrating that Floyd’s respiratory rate in a slow motion video was about 22 at one point, and saying that the normal respiratory rate ranges between 12 and 22 breaths per minute. Tobin was called as a rebuttal witness after the defense team's forensic pathologist David Fowler suggested that prolonged inhalation of carbon monoxide (CO) fumes from the police cruiser's exhaust tailpipe could have been a cause-of-death factor. Tobin cited Floyd's Emergency Room arterial blood
oxygen saturation Oxygen saturation (symbol SO2) is a relative measure of the concentration of oxygen that is dissolved or carried in a given medium as a proportion of the maximal concentration that can be dissolved in that medium at the given temperature. It ca ...
level (98%) as inconsistent with
carbon monoxide poisoning Carbon monoxide poisoning typically occurs from breathing in carbon monoxide (CO) at excessive levels. Symptoms are often described as " flu-like" and commonly include headache, dizziness, weakness, vomiting, chest pain, and confusion. Large ...
.


References

{{DEFAULTSORT:Tobin, Martin 1951 births Living people People from Freshford, County Kilkenny Irish pulmonologists American pulmonologists Alumni of University College Dublin Irish emigrants to the United States University of Texas Health Science Center at Houston faculty University of Miami faculty 20th-century Irish medical doctors 21st-century Irish medical doctors University of Pittsburgh faculty Medical doctors from County Kilkenny