Marjorie C. Caserio
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Marjorie Constance Caserio (née Beckett; February 26, 1929 – April 19, 2021) was an English chemist. In 1975, she was awarded the
Garvan Medal Garvan may refer to: People *Francis Patrick Garvan (1875–1937), American lawyer, president of the Chemical Foundation *Genevieve Garvan Brady (1880–1938), American philanthropist and Papal duchess * Garvan McCarthy (born 1981), retired Irish s ...
by the American Chemical Society.


Early life and education

Caserio was born Marjorie Constance Beckett in
Cricklewood, London Cricklewood is an area of London, England, which spans the boundaries of three London boroughs: London Borough of Barnet, Barnet to the east, London Borough of Brent, Brent to the west and London Borough of Camden, Camden to the south-east. The C ...
, England. She attended the North London Collegiate School and began studying podiatry at Chelsea College, but soon developed a preference for chemistry and graduated with honors in the subject in 1950. She was awarded a Sir John Dill Fellowship by the
English-Speaking Union The English-Speaking Union (ESU) is an international educational membership organistation. Founded by the journalist Sir Evelyn Wrench in 1918, it aims to bring together and empower people of different languages and cultures, by building skill ...
which allowed her to study at Bryn Mawr College in the United States, she earned an M.A. in chemistry in 1951. Her thesis was entitled "The alkaline hydrolysis of ethyl ''p''-alkybenzoates." For a year she worked at the Fulmer Research Institute in rural Stoke Poges, England, researching the effects of
fluoride Fluoride (). According to this source, is a possible pronunciation in British English. is an inorganic, monatomic anion of fluorine, with the chemical formula (also written ), whose salts are typically white or colorless. Fluoride salts typ ...
s on titanium, but disliked the work and decided to seek a Ph.D. in chemistry. She interviewed with
Nobel laureate The Nobel Prizes ( sv, Nobelpriset, no, Nobelprisen) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make out ...
Derek Barton and was accepted to
Birkbeck College Birkbeck, University of London (formally Birkbeck College, University of London), is a public university, public research university, located in Bloomsbury, London, England, and a constituent college, member institution of the federal Universit ...
in London, but was not offered financial aid. Instead, Caserio returned to Bryn Mawr in the U.S., earning her Ph.D. in 1956 with a dissertation entitled "The kinetics of bromination of naphthalene."


Career

Caserio was hired by John D. Roberts for a postdoctoral position at the California Institute of Technology. She spent eight years at Caltech, working on 3- and 4-membered ring compounds, the reactions of
alcohol Alcohol most commonly refers to: * Alcohol (chemistry), an organic compound in which a hydroxyl group is bound to a carbon atom * Alcohol (drug), an intoxicant found in alcoholic drinks Alcohol may also refer to: Chemicals * Ethanol, one of sev ...
s with diazomethane, the hydrolysis of
diaryliodonium salts Unlike its lighter congeners, the halogen iodine forms a number of stable organic compounds, in which iodine exhibits higher formal oxidation states than -1 or coordination number exceeding 1. These are the hypervalent organoiodines, often ca ...
, the deamination of nitrous acid, and benzyne
reaction intermediate In chemistry, a reaction intermediate or an intermediate is a molecular entity that is formed from the reactants (or preceding intermediates) but is consumed in further reactions in stepwise chemical reactions that contain multiple elementary st ...
s in nucleophilic aromatic substitution reactions. She collaborated with Roberts in writing an organic chemistry textbook, ''Basic Principles of Organic Chemistry'', first published in 1964. Notable for its comprehensiveness and then-unusual emphasis on
spectroscopy Spectroscopy is the field of study that measures and interprets the electromagnetic spectra that result from the interaction between electromagnetic radiation and matter as a function of the wavelength or frequency of the radiation. Matter wa ...
, it proved enormously influential in how the subject was taught. Also working with Roberts was chemist Fred Caserio.


University of California, Irvine

In 1964, Caserio was hired as the second faculty member in chemistry at the brand new University of California, Irvine. At UC Irvine she worked on addition reactions in allenes and bonding and reactions of
sulfur Sulfur (or sulphur in British English) is a chemical element with the symbol S and atomic number 16. It is abundant, multivalent and nonmetallic. Under normal conditions, sulfur atoms form cyclic octatomic molecules with a chemical formula ...
compounds. She was one of the first scientists to employ nuclear magnetic resonance spectroscopy to study the kinetics and mechanisms of these organic reactions, and ion cyclotron resonance to study gas-phase reactions. Caserio became a full professor at UC Irvine in 1972, and chair of the chemistry department in 1987.


University of California, San Diego

In 1990, she became vice chancellor for academic affairs at the University of California, San Diego. She later served as interim chancellor, and retired in 1996.


Personal life and death

In 1957, she married Fred Caserio; she became a US citizen the same year. They had two sons. She died in 2021, aged 92, on a trip to Mexico.Obituary
cucea.org. Accessed February 21, 2024.


References


Books

* *


External links


A video interview of Caserio


{{DEFAULTSORT:Caserio, Marjorie 1929 births 2021 deaths Bryn Mawr College alumni California Institute of Technology faculty University of California, Irvine faculty University of California, San Diego administrators Recipients of the Garvan–Olin Medal American women chemists 21st-century American chemists American women academics English emigrants to the United States People from Cricklewood 21st-century American women scientists Naturalized citizens of the United States Graduate Women in Science