Marjorie Bick
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Marjorie Elizabeth Dulcie Bick (11 December 1915 – 18 October 2013) was an Australian biochemist. Born the daughter of Charles William Bick of
Sandringham Sandringham can refer to: Places * Sandringham, New South Wales, Australia * Sandringham, Queensland, Australia * Sandringham, Victoria, Australia **Sandringham railway line **Sandringham railway station **Electoral district of Sandringham * Sand ...
, Marjorie studied at Firbank Girl's Grammar School from 1920 and
matriculated Matriculation is the formal process of entering a university, or of becoming eligible to enter by fulfilling certain academic requirements such as a matriculation examination. Australia In Australia, the term "matriculation" is seldom used now. ...
in 1932 to undertake a Bachelor of Science degree at the University of Melbourne in 1937, then completed a Master of Science Degree at Melbourne in 1941.


Biochemist

Bick began her career as a biochemist at the
Walter and Eliza Hall Institute of Medical Research WEHI (), previously known as the Walter and Eliza Hall Institute of Medical Research, and as the Walter and Eliza Hall Institute, is Australia's oldest medical research institute. Sir Frank Macfarlane Burnet, who won the Nobel Prize in 1960 for ...
, which beside the
Commonwealth Serum Laboratories CSL Limited is an Australian multinational specialty biotechnology company that researches, develops, manufactures, and markets products to treat and prevent serious human medical conditions. CSL's product areas include blood plasma derivative ...
, was then one of the few institutions offering women in Australia the opportunity of a scientific career. She was amongst a number of notable biochemists, mostly women, like Beryl Splatt and Lorna Silvester who had a major influence on the nation's development of clinical biochemistry, She worked in the field of blood transfusion specialising in the production of
blood serum Serum () is the fluid and solute component of blood which does not play a role in clotting. It may be defined as blood plasma without the clotting factors, or as blood with all cells and clotting factors removed. Serum includes all proteins not u ...
in the laboratory. In 1939 she was seconded to the
Australian Red Cross Society The Australian Red Cross, formally the Australian Red Cross Society, is a humanitarian aid and community services charity in Australia. Tracing its history back to 1923 and being incorporated by royal charter in 1941, the Australian Red Cro ...
(Victorian Division) Blood Transfusion Services. In 1940 she drove from Melbourne with Sheila Summons, Nancy Hayward and Kathleen Gilles to attend the Science Congress in Canberra where she discussed problems in blood transfusion with the Adelaide committee.


World War Two

Bick was invited to the USA and Canada with Dr Lucy Bryce to study developments in blood transfusion,  and worked at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
in the Plasma Fractionation Laboratory. Her research found a direct correlation between the
platelet count Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby ini ...
of human blood, and its vasoconstrictor activity after clotting. Returning to Australia, she became biochemist to the Australian Red Cross Society, overseeing Victoria's Red Cross Blood Bank during WW2, during which she held the rank of captain in the
Australian Army Medical Corps The Royal Australian Army Medical Corps (RAAMC) is the branch of the Australian Army responsible for providing medical care to Army personnel. The AAMC was formed in 1902 through the amalgamation of medical units of the various Australian coloni ...
. By 1944 she was Honorary Director of Training and Equipment at the Blood Bank in the
Royal Melbourne Hospital The Royal Melbourne Hospital (RMH), located in Parkville, Victoria, an inner suburb of Melbourne, is one of Australia's leading public hospitals. It is a major teaching hospital for tertiary health care with a reputation in clinical research. Th ...
and traveled again with Dr Bryce to study in America. They arrived on the ''S.S.'' ''Kanangoora'' in March 1945 and visited the Hooper Research Foundation in
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then traveled to
New Orleans New Orleans ( , ,New Orleans
Merriam-Webster.
; french: La Nouvelle-Orléans , es, Nuev ...
and
Washington Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered o ...
, and attended a conference of the Blood Substitutes Committee of the
National Research Council National Research Council may refer to: * National Research Council (Canada), sponsoring research and development * National Research Council (Italy), scientific and technological research, Rome * National Research Council (United States), part of ...
. Bryce then traveled to investigate clinical methods while Bick stayed on in Boston for eighteen months undertaking laboratory work on
plasma fractionation Blood plasma fractionation are the general processes separating the various components of blood plasma, which in turn is a component of blood obtained through blood fractionation. Plasma-derived immunoglobulins are giving a new narrative to health ...
in the Department of Physical Chemistry at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
under Professor Edwin J. Cohn, a pioneer in the field. She and Bryce reported on war conditions and attitudes to Australia in America and on the mass production methods at the
Cutter Laboratories Cutter Laboratories was a family-owned pharmaceutical company located in Berkeley, California, founded by Edward Ahern Cutter in 1897. Cutter's early products included anthrax vaccine, hog cholera (swine fever) virus, and anti-hog cholera serum ...
of packing and shipping plasma and whole blood to be parachuted into the Pacific war zones. Their research coincided with a plan to expand the Blood Bank into a new floor of the Royal Melbourne Hospital.


Post-war career

In 1949, Bick concluded nine years of work for the Red Cross Blood Transfusion Service and joined the
Alfred Hospital The Alfred Hospital, also known as The Alfred or Alfred Hospital, is a leading tertiary teaching hospital in Melbourne, Victoria. It is the second oldest hospital in Victoria, and the oldest Melbourne hospital still operating on its original site ...
as a Senior Biochemist where she oversaw the management and implementation of new laboratory procedures at the Hospital. Recipient of a
Fulbright Scholarship The Fulbright Program, including the Fulbright–Hays Program, is one of several United States Cultural Exchange Programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of ...
in 1955, she studied new techniques in the USA at the
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...
, Boston, and in the United Kingdom at the Isotope School of the Atomic Energy Commission and at
University College, London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = ...
. Bick was a founding member and Victorian representative 1961–1963 of the Australasian Association of Clinical Biochemists (AACB) which was established 26 May 1961 during an
ANZAAS The Australian and New Zealand Association for the Advancement of Science (ANZAAS) is an organisation that was founded in 1888 as the Australasian Association for the Advancement of Science to promote science. It was modelled on the British A ...
Congress in
Brisbane Brisbane ( ) is the capital and most populous city of the states and territories of Australia, Australian state of Queensland, and the list of cities in Australia by population, third-most populous city in Australia and Oceania, with a populati ...
. Bick then pursued her interest in environmental science and was awarded a Research Scholarship for research at the National Institute of Environmental Health in
North Carolina North Carolina () is a state in the Southeastern region of the United States. The state is the 28th largest and 9th-most populous of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, Georgia and So ...
1967–1969, and then 1969–1971 worked as a biochemist at the Medical Research Council, Division of Clinical Chemistry, in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and North ...
, publishing on the effect of human exposure to pesticides and to hydrocarbons. Her analysis by
gas-liquid chromatography Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substance, ...
of biopsy specimens of human body fat collected in 1965 from 53 individuals found DDT-derived material and dieldrin present in all samples; a mean concentration of total DDT equivalent stored was 1.81 ppm, and the mean concentration of dieldrin was 0.046 ppm. In other investigations she found that occupational exposure to
esterase An esterase is a hydrolase enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis. A wide range of different esterases exist that differ in their substrate specificity, their protein structure, ...
inhibitors used as pesticides in a group of orchardists, when spraying with reasonable care, is sufficient to cause a decrease in red-cell
acetylcholinesterase Acetylcholinesterase (HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme Enzymes () are proteins that a ...
activity. Bick returned to Australia in 1972 and worked in Pre-Clinical Drug Evaluation at the
Department of Health A health department or health ministry is a part of government which focuses on issues related to the general health of the citizenry. Subnational entities, such as states, counties and cities, often also operate a health department of their ow ...
in
Canberra Canberra ( ) is the capital city of Australia. Founded following the federation of the colonies of Australia as the seat of government for the new nation, it is Australia's largest inland city and the eighth-largest city overall. The ci ...
and during the 1970s and 80s contributed to Drug Toxicity Evaluation at the
Therapeutic Goods Administration The Therapeutic Goods Administration (TGA) is the medicine and therapeutic regulatory agency of the Australian Government. As part of the Department of Health and Aged Care, the TGA regulates the quality, supply and advertising of medicines, pa ...
.


Personal life

In the 1950s Bick was a member and secretary of the first all-women sailing club, The Victorian Ladies' Yacht Club. Retired in 1980, Bick ran a Victorian country Post Office and general store, later living in
Canberra Canberra ( ) is the capital city of Australia. Founded following the federation of the colonies of Australia as the seat of government for the new nation, it is Australia's largest inland city and the eighth-largest city overall. The ci ...
and then
Brighton Brighton () is a seaside resort and one of the two main areas of the City of Brighton and Hove in the county of East Sussex, England. It is located south of London. Archaeological evidence of settlement in the area dates back to the Bronze A ...
. She died on 18 October 2013.


Publications

* * * * * * * * * * * * * * * *


References

{{DEFAULTSORT:Bick, Marjorie 1915 births 2013 deaths Australian women scientists Australian biochemists Australian haematologists Australian scientists Environmental scientists WEHI staff University of Melbourne alumni University of Melbourne women 20th-century women scientists