Marie Jean Pierre Flourens (13 April 1794 – 6 December 1867), father of

Gustave Flourens Gustave Flourens (4 August 1838 in Paris – 3 April 1871) was a French Revolutionary leader and writer, son of the physiologist Jean Pierre Flourens (who was Professor at the ''Collège de France'' and deputy in 1838-1839). He was also the e ...

, was a French physiologist, the founder of experimental

brain A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a ve ...

science, and a pioneer in anesthesia.

Biography

Flourens was born at

Maureilhan Maureilhan (; oc, Maurelhan) is a Communes of France, commune in the Hérault Departments of France, department in southern France. Population See also *Communes of the Hérault department References

Communes of Hérault {{Hé ...

, near Béziers, in the ''

département In the administrative divisions of France, the department (french: département, ) is one of the three levels of government under the national level (" territorial collectivities"), between the administrative regions and the communes. Ninety ...

'' of

Hérault Hérault (; oc, Erau, ) is a department of the region of Occitania, Southern France. Named after the Hérault River, its prefecture is Montpellier. It had a population of 1,175,623 in 2019.medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pr ...

at Montpellier, where he received the degree of

doctor Doctor or The Doctor may refer to: Personal titles * Doctor (title), the holder of an accredited academic degree * A medical practitioner, including: ** Physician ** Surgeon ** Dentist ** Veterinary physician ** Optometrist *Other roles ** ...

in 1813. In the following year he went to

Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), ma ...

, carrying an introduction from

A. P. de Candolle Augustin Pyramus (or Pyrame) de Candolle (, , ; 4 February 17789 September 1841) was a Swiss botanist. René Louiche Desfontaines launched de Candolle's botanical career by recommending him at a herbarium. Within a couple of years de Candolle ...

, the botanist, to Georges Cuvier, who received him kindly, and took an interest in him. In Paris, Flourens engaged in physiological research, occasionally contributing to publications; and, in 1821, at the Athénée, he gave a course of lectures on the physiological theory of the sensations, which attracted much attention amongst men of science. In 1815, Flourens pioneered the experimental method of carrying out localized

lesions A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals. Types There is no designated classifi ...

of the brain in living rabbits and

pigeons Columbidae () is a bird family consisting of doves and pigeons. It is the only family in the order Columbiformes. These are stout-bodied birds with short necks and short slender bills that in some species feature fleshy ceres. They primarily ...

and carefully observing their effects on motricity, sensibility and behavior. His intention was to investigate localisationism, i.e., whether different parts of the brain had different functions, as the Austrian physician

Franz Joseph Gall Franz Josef Gall (; 9 March 175822 August 1828) was a German neuroanatomist, physiologist, and pioneer in the study of the localization of mental functions in the brain. Claimed as the founder of the pseudoscience of phrenology, Gall was an ea ...

, the founder of phrenology, was proposing. The trouble was that Gall did not use a proper scientific approach to his affirmations. In 1825, Flourens was elected as a member to the

American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...

. Flourens was able to demonstrate convincingly for the first time that the main divisions of the brain were indeed responsible for largely different functions. By removing the

cerebral hemisphere The vertebrate cerebrum (brain) is formed by two cerebral hemispheres that are separated by a groove, the longitudinal fissure. The brain can thus be described as being divided into left and right cerebral hemispheres. Each of these hemispheres ...

s, for instance, all perceptions, motricity, and

judgment Judgement (or US spelling judgment) is also known as ''adjudication'', which means the evaluation of evidence to make a decision. Judgement is also the ability to make considered decisions. The term has at least five distinct uses. Aristotle s ...

were abolished. The removal of the cerebellum affected the animal's equilibrium and motor coordination, while the destruction of the brainstem (medulla oblongata) caused death. These experiments led Flourens to the conclusion that the cerebral hemispheres are responsible for higher cognitive functions, that the cerebellum regulates and integrates movements, and that the medulla controls vital functions, such as circulation,

respiration Respiration may refer to: Biology * Cellular respiration, the process in which nutrients are converted into useful energy in a cell ** Anaerobic respiration, cellular respiration without oxygen ** Maintenance respiration, the amount of cellul ...

and general bodily stability. On the other hand, he was unable (probably because his experimental subjects have relatively primitive cortex) to find specific regions for

memory Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. It is the retention of information over time for the purpose of influencing future action. If past events could not be remembered ...

and cognition, which led him to believe that they are represented in a diffuse form around the brain. So, different functions could indeed be ascribed to particular regions of the brain, but a finer localization was lacking. Flourens, by destroying the horizontal semicircular canal of

pigeon Columbidae () is a bird family consisting of doves and pigeons. It is the only family in the order Columbiformes. These are stout-bodied birds with short necks and short slender bills that in some species feature fleshy ceres. They primarily ...

s, noted that they continue to fly in a circle, showing the purpose of the semicircular canals. Flourens was chosen by Cuvier in 1828 to deliver a course of lectures on natural history at the

Collège de France The Collège de France (), formerly known as the ''Collège Royal'' or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment ('' grand établissement'') in France. It is located in Paris n ...

, and in the same year became, in succession to LAG Bosc, a member of the Institute, in the division "Economic rurale." In 1830 he became Cuvier's substitute as lecturer on human

anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having it ...

at the Jardin du Roi, and in 1832 was elected to the post of titular professor, which he vacated for the professorship of comparative anatomy created for him at the museum of the Jardin the same year. In 1833 Flourens, in accordance with the dying request of Cuvier, was appointed a perpetual secretary of the Academy of Sciences; and in 1838 he was returned as a deputy for the ''arrondissement'' of Béziers. In 1840 he was elected, in preference to

Victor Hugo Victor-Marie Hugo (; 26 February 1802 – 22 May 1885) was a French Romantic writer and politician. During a literary career that spanned more than sixty years, he wrote in a variety of genres and forms. He is considered to be one of the great ...

, to succeed Jean François Michaud at the

French Academy French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ...

; and in 1845 he was created a commander of the ''

légion d'honneur The National Order of the Legion of Honour (french: Ordre national de la Légion d'honneur), formerly the Royal Order of the Legion of Honour ('), is the highest French order of merit, both military and civil. Established in 1802 by Napoleon ...

'', and in the next year a peer of France. In 1841, he was elected a foreign member of the Royal Swedish Academy of Sciences. In March 1847 Flourens drew the attention of the Academy of Sciences to the

anesthetic An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness. They may be divided into two ...

effect of chloroform on animals. On the revolution of 1848 he withdrew completely from political life; and in 1855 he accepted the professorship of natural history at the

. He died at Montgeron, near Paris on 6 December 1867.

Opposition to Darwinism

Flourens was an opponent of Darwinism and criticized the idea of

natural selection Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the heritable traits characteristic of a population over generations. Cha ...

. In 1864, he authored ''Examen du livre du M. Darwin sur l'Origine des Espèces''. He refuted the arguments of

spontaneous generation Spontaneous generation is a superseded scientific theory that held that living creatures could arise from nonliving matter and that such processes were commonplace and regular. It was hypothesized that certain forms, such as fleas, could arise f ...

. He was a

creationist Creationism is the religious belief that nature, and aspects such as the universe, Earth, life, and humans, originated with supernatural acts of divine creation. Gunn 2004, p. 9, "The ''Concise Oxford Dictionary'' says that creationism is 'th ...

and defended the fixity of species.Simonton, Dean Keith. (2004). ''Creativity in Science: Chance, Logic, Genius, and Zeitgeist''. Cambridge University Press. p. 125. Flourens criticized

Charles Darwin Charles Robert Darwin ( ; 12 February 1809 – 19 April 1882) was an English naturalist, geologist, and biologist, widely known for his contributions to evolutionary biology. His proposition that all species of life have descended ...

for personifying nature. He argued that natural selection is a contradictory term as nature does not select.Huxley, Thomas Henry. (1880)
''Lay Sermons, Addresses, and Reviews''
London: Macmillan & Co. pp. 314-319. Flourens' book was never translated into English and no reviewers attempted to refute his arguments in detail. However,

Thomas Henry Huxley Thomas Henry Huxley (4 May 1825 – 29 June 1895) was an English biologist and anthropologist specialising in comparative anatomy. He has become known as "Darwin's Bulldog" for his advocacy of Charles Darwin's theory of evolution. The stori ...

took issue with his criticism of Darwinism, noting that "his objections to details are of the old sort, so battered and hackneyed on this side of the Channel, that not even a Quarterly Reviewer could be induced to pick them up for the purpose of pelting Mr. Darwin over again."

Bibliography

Besides numerous shorter scientific memoirs, Flourens published: *''Essai sur quelques points de la doctrine de la revulsion et de la derivation'' (Montpellier, 1813) *''Experiences sur le système nerveux'' (Paris, 1825) *''Cours sur la génération, l'ovologie, et l'einhryologie'' (1836) *''Analyse raisonnée des travaux de G. Cuvier'' (1841) *''Recherches sur le développement des os et des dents'' (1842) *''Anatomie générale de la peau et des membranes muqueuses'' (1843) *'' Buffon, histoire de ses travaux et de ses idées'' (1844) *''Fontenelle, ou de la philosophie moderne relativement aux sciences physiques'' (1847) *''Théorie expérémentale de la formation des os'' (1847) *''Œuvres complètes de Buffon'' (1853) *''De la longévité humaine et de la quantité de vie sur le globe'' (1854), numerous editions *''Histoire de la découverte de la circulation du sang'' (1854) *''Cours de physiologie comparée'' (1856) *''Recuesi des lloges historiques'' (1856) *''De la vie et de l'intelligence'' (1858) *''De la raison, du genie, et de la folie'' (1861) *''Ontologie naturelle'' (1861)
''Examen du livre du M. Darwin sur l'Origine des Espèces''
(1864).

Biography

Opposition to Darwinism

Bibliography

References

Further reading