Marcus E. Raichle (born March 15, 1937) is an American neurologist at the

Washington University School of Medicine Washington University School of Medicine (WUSM) is the medical school of Washington University in St. Louis in St. Louis, Missouri. Founded in 1891, the School of Medicine has 1,260 students, 604 of which are pursuing a medical degree with ...

Saint Louis, Missouri St. Louis () is the second-largest city in Missouri, United States. It sits near the confluence of the Mississippi and the Missouri Rivers. In 2020, the city proper had a population of 301,578, while the bi-state metropolitan area, which ...

. He is a professor in the Department of Radiology with joint appointments in Neurology, Neurobiology and Biomedical Engineering. His research over the past 40 years has focused on the nature of functional brain imaging signals arising from PET and

fMRI Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area o ...

and the application of these techniques to the study of the human

brain The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head ( cephalization), usually near organs for special ...

in health and disease. He received the

Kavli Prize The Kavli Prize was established in 2005 as a joint venture of the Norwegian Academy of Science and Letters, the Norwegian Ministry of Education and Research, and the Kavli Foundation. It honors, supports, and recognizes scientists for outstan ...

in Neuroscience “for the discovery of specialized brain networks for memory and cognition", together with Brenda Milner and John O’Keefe in 2014.

Career

Noteworthy accomplishments of Marcus Raichle include the discovery of the relative independence of blood flow and oxygen consumption during changes in brain activity which provided the physiological basis of fMRI; the discovery of a default mode of brain function (i.e., organized intrinsic activity) and its signature system, the brain’s default mode network; and, the discovery that aerobic glycolysis contributes to brain function independent of

oxidative phosphorylation Oxidative phosphorylation (UK , US ) or electron transport-linked phosphorylation or terminal oxidation is the metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing chemical energy in order to produce adenosine t ...

Honors

* Member:

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...

Institute of Medicine The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, En ...

American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, ...

*Foreign member: The Norwegian Academy of Science and Letters * Fellow:

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsi ...

Awards

In 2001, he was a co-recipient of

Grawemeyer Award The Grawemeyer Awards () are five awards given annually by the University of Louisville. The prizes are presented to individuals in the fields of education, ideas improving world order, music composition, religion, and psychology. The religion awa ...

in Psychology, with Michael Posner and Steven Petersen of the

University of Louisville The University of Louisville (UofL) is a public research university in Louisville, Kentucky. It is part of the Kentucky state university system. When founded in 1798, it was the first city-owned public university in the United States and one of ...

. In 2010, he was awarded the

Metlife Foundation Award for Medical Research in Alzheimer's Disease The Metlife Foundation Award for Medical Research in Alzheimer's Disease were awarded annually from 1986 to 2016 to recognize scientific contributions toward a better understanding of the underlying causes, prevention, and treatments of Alzheimer' ...

along with

Randy L. Buckner Randy L. Buckner (born June 15, 1970) is an American neuroscientist and psychologist whose research focuses on understanding how large-scale brain circuits support mental function and how dysfunction arises in illness. Buckner is a Professor of ...

, and the Ariëns Kappers Medal from the

Royal Netherlands Academy of Arts and Sciences The Royal Netherlands Academy of Arts and Sciences ( nl, Koninklijke Nederlandse Akademie van Wetenschappen, abbreviated: KNAW) is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed ...

. In 2014, he was a co-recipient of the

in Neuroscience, awarded by the

Norwegian Academy of Science and Letters The Norwegian Academy of Science and Letters ( no, Det Norske Videnskaps-Akademi, DNVA) is a learned society based in Oslo, Norway. Its purpose is to support the advancement of science and scholarship in Norway. History The Royal Frederick Unive ...

, with Brenda Milner of the Montreal Neurological Institute at

McGill University McGill University (french: link=no, Université McGill) is an English-language public research university located in Montreal, Quebec, Canada. Founded in 1821 by royal charter granted by King George IV,Frost, Stanley Brice. ''McGill Universit ...

and John O’Keefe of

University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = � ...

Selected publications

* * * * * * * * * * *

References

External links

Official site
{{DEFAULTSORT:Raichle, Marcus E. Living people 1937 births American consciousness researchers and theorists Attention American physiologists American cognitive neuroscientists American neurologists Behavioral neuroscientists Members of the United States National Academy of Sciences Kavli Prize laureates in Neuroscience Members of the National Academy of Medicine