Manuel Rodríguez Gómez
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Manuel Rodríguez Gómez (July 4, 1928 – January 21, 2006) was an American
neurologist Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...
most noted for his work on
tuberous sclerosis Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant genetic disease that causes non-cancerous tumours to grow in the brain and on other vital organs such as the kidneys, heart, liver, eyes, lungs and skin. A combination ...
, a rare
genetic disorder A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosomal abnormality. Although polygenic disorders ...
.


Life

Manuel Gómez was born in the
Spanish Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Cana ...
city of
Minaya Minaya is a municipality in Albacete Albacete (, also , ; ar, ﭐَلبَسِيط, Al-Basīṭ) is a city and municipality in the Spanish autonomous communities of Spain, autonomous community of Castilla–La Mancha, and capital of the pro ...
in
La Mancha La Mancha () is a natural and historical region located in the Spanish provinces of Albacete, Cuenca, Ciudad Real, and Toledo. La Mancha is an arid but fertile plateau (610 m or 2000 ft) that stretches from the mountains of Toledo to the ...
. He spent his childhood outside Sevilla in a town called Alcala de Guadaira, where his father had a pharmacy, and summers in Cadiz. As a child he recalled seeing the great flamenco singer, Bernardo, El de los Lobitos, walking on the street. He attended boarding school with his brother and was schooled by a group of strict priests. Recently the mayor of Alcala renamed a street Calle Manuel Rodriguez Gomez. He lived through the Spanish Civil War and recalled at least one near miss when he and his older brother were rescued from hiding under a bridge by an old man when they heard the sound of a German dive bomber. After running away and hearing the explosion they looked up to see that the bridge that had been the target was demolished. As his father had supported the Republic he felt insecure after Franco won the war. Thus when he was 12 years old, his family took the opportunity to move to
Cuba Cuba ( , ), officially the Republic of Cuba ( es, República de Cuba, links=no ), is an island country comprising the island of Cuba, as well as Isla de la Juventud and several minor archipelagos. Cuba is located where the northern Caribbea ...
. He studied violin as a young man, and while he had a great interest in a musical career or in studying mathematics, he entered medical school at the age of 18, and was regularly near the top of his class. After one difficult medical school exam he and his friends got carried away by the celebration and shouted protests against the dictator
Batista Batista is a Spanish language, Spanish or Portuguese language, Portuguese surname. Notable persons with the name include: * Batista (footballer, born 1955), Brazilian football player * Dave Bautista, American actor and professional wrestler, also ...
. He and his friends spent the evening in jail, although all were released unharmed by morning. He received his doctorate in medicine at the
Universidad de la Habana The University of Havana or (UH, ''Universidad de La Habana'') is a university located in the Vedado district of Havana, the capital of the Republic of Cuba. Founded on January 5, 1728, the university is the oldest in Cuba, and one of the first ...
in 1952. After graduation he secured an internship in Michael Reese Hospital in Chicago, leaving his parents and siblings in Havana. He met Joan A. Stormer while working at Michael Reese and married her in 1954. His four sons have pursued academic and medical careers; one is a neurologist, one a developmental neurobiologist, one is a wildlife biologist and one is a professor of art. He had seven grandchildren.


Career

* 1952: Doctorate in medicine from the
Universidad de la Habana The University of Havana or (UH, ''Universidad de La Habana'') is a university located in the Vedado district of Havana, the capital of the Republic of Cuba. Founded on January 5, 1728, the university is the oldest in Cuba, and one of the first ...
,
Cuba Cuba ( , ), officially the Republic of Cuba ( es, República de Cuba, links=no ), is an island country comprising the island of Cuba, as well as Isla de la Juventud and several minor archipelagos. Cuba is located where the northern Caribbea ...
. * 1952–1953: Internship at
Michael Reese Hospital Michael Reese Hospital and Medical Center was an American hospital located in the Bronzeville neighborhood of Chicago, Illinois. Founded in 1881, Michael Reese Hospital was a major research and teaching hospital and one of the oldest and largest ...
,
Chicago (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...
. * 1953–1954: Residency in
pediatrics Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until th ...
at the
University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...
. * 1954–1956: Residency in
neurology Neurology (from el, wikt:νεῦρον, νεῦρον (neûron), "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine), medicine dealing with the diagnosis and treatment of all categories of co ...
at the University of Michigan, where he received an MS degree in neuroanatomy. * 1956–1957: Fellow in pediatric neurology at
University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...
. * 1957–1958: Faculty of neurology at the
State University of New York at Buffalo The State University of New York at Buffalo, commonly called the University at Buffalo (UB) and sometimes called SUNY Buffalo, is a public research university with campuses in Buffalo and Amherst, New York. The university was founded in 1846 ...
. * 1958–1959: Studied at the
Institute of Neurology The UCL Queen Square Institute of Neurology is an institute within the Faculty of Brain Sciences of University College London, University College London (UCL) and is located in London, United Kingdom. Together with the National Hospital for Neur ...
,
Queen Square, London Queen Square is a garden square in the Bloomsbury district of central London. Many of its buildings are associated with medicine, particularly neurology. Construction Queen Square was originally constructed between 1716 and 1725. It was forme ...
. * 1960–1964: Associate professor of neurology at the
Wayne State University School of Medicine The Wayne State University School of Medicine (WSUSOM) is the medical school of Wayne State University, a public research university in Detroit, Michigan. It enrolls more than 1,500 students in undergraduate medical education, master's degree, Ph ...
,
Detroit Detroit ( , ; , ) is the largest city in the U.S. state of Michigan. It is also the largest U.S. city on the United States–Canada border, and the seat of government of Wayne County. The City of Detroit had a population of 639,111 at th ...
. Certified in neurology by the
ABPN The American Board of Psychiatry and Neurology, Inc. (ABPN) is a not-for-profit corporation that was founded in 1934 following conferences of committees appointed by the American Psychiatric Association, the American Neurological Association, an ...
. * 1964–1984: Head of the department of Pediatric Neurology at
Mayo Clinic The Mayo Clinic () is a nonprofit American academic medical center focused on integrated health care, education, and research. It employs over 4,500 physicians and scientists, along with another 58,400 administrative and allied health staff, ...
,
Rochester Rochester may refer to: Places Australia * Rochester, Victoria Canada * Rochester, Alberta United Kingdom *Rochester, Kent ** City of Rochester-upon-Medway (1982–1998), district council area ** History of Rochester, Kent ** HM Prison ...
. He became Professor of Pediatric Neurology in 1974 and Professor Emeritus in 1994. * 2000: Retired.


Organisations

Manuel Gómez was a charter member of the American Child Neurology Society, the International Child Neurology Association (ICNA) and the Latin American Academy of Pediatric Neurology. He was honorary member of a number of pediatric and neurology societies, including the ''Sociedad Española de Neurología'' (SEN) and ''Sociedad Española de Neurología Pediátrica'' (SENP).


Awards

* The
Santiago Ramón y Cajal Santiago Ramón y Cajal (; 1 May 1852 – 17 October 1934) was a Spanish neuroscientist, pathologist, and histologist specializing in neuroanatomy and the central nervous system. He and Camillo Golgi received the Nobel Prize in Physiology or Med ...
Award from The Iberoamerican Academy of Pediatric Neurology in 1995. * The Hower Award from the Child Neurology Society. * The Tuberous Sclerosis Alliance established in 1995 the ''Manuel R. Gomez Professional Recognition Award'' in his honor. This award is for "creative or pioneering efforts that have appreciably improved either the understanding of the disease or the clinical care available for individuals with tuberous sclerosis."


Tuberous sclerosis

Manuel Gómez was most interested in neurocutaneous syndromes, and especially
tuberous sclerosis Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant genetic disease that causes non-cancerous tumours to grow in the brain and on other vital organs such as the kidneys, heart, liver, eyes, lungs and skin. A combination ...
. In 1967 he broke the established wisdom that tuberous sclerosis was defined by
Vogt During the Middle Ages, an (sometimes given as modern English: advocate; German: ; French: ) was an office-holder who was legally delegated to perform some of the secular responsibilities of a major feudal lord, or for an institution such as ...
's triad of
mental retardation Intellectual disability (ID), also known as general learning disability in the United Kingdom and formerly mental retardation,Rosa's Law, Pub. L. 111-256124 Stat. 2643(2010). is a generalized neurodevelopmental disorder characterized by signific ...
,
epilepsy Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical ...
and adenoma sebaceum (a papular facial rash). He co-published a paper showing that about a third of patients had normal intelligence. In 1979, he edited the
monograph A monograph is a specialist work of writing (in contrast to reference works) or exhibition on a single subject or an aspect of a subject, often by a single author or artist, and usually on a scholarly subject. In library cataloging, ''monograph ...
''Tuberous Sclerosis Complex'', the first and, for over twenty years, the only textbook on the disease. In it, he established a comprehensive
diagnostic criteria Medical diagnosis (abbreviated Dx, Dx, or Ds) is the process of determining which disease or condition explains a person's symptoms and signs. It is most often referred to as diagnosis with the medical context being implicit. The information req ...
for tuberous sclerosis. This book has been translated into Spanish and has been revised twice: in 1988 and 1999.


Publications

* * * Manuel Gómez was the author of more than 170
scientific paper : ''For a broader class of literature, see Academic publishing.'' Scientific literature comprises scholarly publications that report original empirical and theoretical work in the natural and social sciences. Within an academic field, scienti ...
s including 93
peer-reviewed Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (peers). It functions as a form of self-regulation by qualified members of a profession within the relevant field. Peer review ...
articles.


See also

*
Timeline of tuberous sclerosis The history of tuberous sclerosis (TSC) research spans less than 200 years. TSC is a rare, multi-system genetic disease that can cause benign tumours to grow on the brain or other vital organs such as the kidneys, heart, eyes, lungs, and skin. A ...


References

* * * * * {{DEFAULTSORT:Gomez, Manuel Rodriguez 1928 births 2006 deaths American neurologists Deaths from Parkinson's disease Neurological disease deaths in the United States University of Michigan Medical School alumni Wayne State University faculty University of Havana alumni Spanish emigrants to Cuba University of Chicago staff Cuban emigrants to the United States