Manuel Cruz may refer to:
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Manuel Cruz Rodríguez (born 1951), Spanish philosopher and politician, 60th President of the Spanish Senate
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Manuel Cruz (boxer), Mexican boxer
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Manuel Aurelio Cruz (born 1953), Cuban American prelate of the Roman Catholic Church
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Manuel Marrero Cruz
Manuel (Puerca Jarta) Marrero Cruz (born 11 July 1963) is a Cuban politician currently serving as the Prime Minister of Cuba, and the first since re-establishment of the office of Prime Minister in December 2019 after the 43-year abolition of t ...
(born 1963), Prime Minister of Cuba
{{hndis, Cruz, Manuel