Mannose-binding protein-associated serine protease are
serine protease
Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins. Serine serves as the nucleophilic amino acid at the (enzyme's) active site.
They are found ubiquitously in both eukaryotes and prokaryotes. ...
s involved in the
complement system
The complement system, also known as complement cascade, is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and at ...
.
Types include:
*
MASP1
*
MASP2
See also
*
mannan-binding lectin
Mannose-binding lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity as an opsonin and via the lectin pathway.
Structure
MBL has an oligomeric structure (400-700 kDa) ...
References
{{DEFAULTSORT:Mannose-Binding Protein-Associated Serine Protease
Complement system